Search PubMed⌕ Search

Biomedical subjects

N I Aleksandrova

Publications and source records attributed to N I Aleksandrova.

At least 19 recordsLinked to original sources
PubMed2003

[Criteria for the clinical cure of tuberculosis of the eye].

The results of examination were analyzed in 314 patients with tuberculosis of the eye, including 120 patients having its inactive phase. Tuberculin skin tests were performed in 31 patients; fluorescence angiography and photostress tests were conducted in 122 patients, and 120 patients underwent lacrimal fluid crystallography. To define the cure rate in tuberculosis of the eye, it is necessary to have a complex of criteria: no clinical signs of active tuberculous inflammation in the ocular tunics and environments; no clinical, X-ray, and laboratory manifestations of tuberculosis of other organs; no focal and significant overall reaction to tuberculin injected in doses of 2 and 50 TU. If there are contraindications to tuberculin skin tests to conclude whether the disease is cured, it is necessary to use fluorescence angiography of the fundus of the eye, lacrimal fluid crystallography, and/or photostress tests in combination with biochemical and immunological blood studies.

Adolescent↗
PubMed2001

[Criteria for clinical recovery in ocular tuberculosis].

The paper analyzes the results of examination of 314 patients with ocular tuberculosis, 120 of them had quiescent tuberculosis. Thirty one patients underwent tuberculin tests; 122 had fluorescence angiography and photo stress test; 120, lacrimal crystallography. To determine the degree of recovery requires a complex of criteria: neither clinical signs of active tuberculous inflammation in the retina and medium of the eye, no clinical, X-ray, and laboratory manifestations of tuberculosis of other sites, or a focal and much significant overall response to tuberculin in doses of 2 TE and 50 TE. If there are contraindications to tuberculin tests, a conclusion on recovery should be made by using fluorescence angiography of the fundus of the eye, crystallography of the tear and/or photo stress test in combination with blood biochemical and immunological studies.

Adult↗
PubMed2001

[Prospects for predicting the life expectancy of patients with chronic obstructive lung disease for refining indicators for lung transplantation].

Success of lung transplantation is largely determined by the patients' timely referral for surgery. However, the determinants of survival in patients with chronic obstructive pulmonary disease (COPD), potential lung recipients are to be established. To reveal the determinants of survival in patients with terminal respiratory failure, the data from a follow-up of 59 patients with COPD who met the generally accepted requirements for the recipients of an isolated lung were analyzed. The analysis of some clinical, functional, hemodynamic parameters established that the level of hypoxemia and the value of pulmonary systolic pressure were of the greatest prognostic value. The values of external respiratory function did not affect the patients' survival. Thus, patients with COPD should undergo lung transplantation if they have a pulmonary systolic pressure of over 50 mm Hg, pO2 of under 60 mm Hg, and no benefits from their conservative therapy.

Humans↗
PubMed1998

[Specific features of therapeutical and diagnostic process at the Vyborg-3 sanatorium under present day socioeconomic conditions].

The Vyborg-3 republican sanatorium is intended to serve 210 patients with ocular tuberculosis. A total of 2521 histories of patients admitted to the sanatorium from different regions of the country were examined. A fourth of the patients needed differential diagnostic studies. In 9% of patients, the tuberculous etiology of eye diseases was excluded. Patients with hematogenic severe and complicated ocular tuberculosis are prevalent every year. The proportion of complicated forms of ocular tuberculosis (cataract, retinal lesions, uveal glaucoma, fibrosis of the vitreous body) is 28%. Therapeutical efficiency in the underlying disease is 92%.

Ambulatory Care Facilities↗
PubMed1997

[Treatment effectiveness of patients with ocular tuberculosis at specialized sanatoria].

The outcomes of treatment of 2908 patients with ocular tuberculosis who were treated at the Vyborg-3, Krasnyi Val, and Plyos sanatoria in 1993 - 1995 are analyzed. These sanatoria used the common guide in evaluating the efficacy of treatment, namely a separate assessment of the outcomes of treatment of the underlying and concurrent diseases. There were no statistical significant differences in therapeutical efficiency at these sanatoria. Therapeutical benefits were obtained in 99.8% of patients in the active phase of the disease.

Adult↗
PubMed1991

[The level of biogenic amines in bronchi of patients with chronic obstructive bronchitis].

Histamine and serotonin levels were measured in expired air humidity condensate (EAHC), bronchoalveolar lavage fluid and sputum of 9 patients with chronic nonobstructive bronchitis and 25 healthy controls. It was found that concentration of biogenic amines depended on the form of chronic bronchitis, activity of bronchial inflammation, characteristics of bronchial obstruction, degree of respiratory insufficiency. EAHC furnished most complete information.

Adult↗
PubMed1990

[Respiratory viral infection and the immune reactivity of patients with different forms of bronchitis].

Virological and immunological examinations made in 258 persons with different forms of bronchitis (acute, relapsing, chronic nonobstructive and obstructive) made it possible to establish a correlation between the forms of bronchitis and the intensity of immunosuppression as well as between the variety and duration of respiratory virus infections, which may indicate that viruses are implicated in the pathogenesis of both acute and chronic processes.

Adolescent↗