Biomedical subjects

N Hurwitz

Publications and source records attributed to N Hurwitz.

40 records · Page 3Linked to original sources

PubMedDate not supplied

Neonatal neurofibromatosis: unusual manifestations with malignant clinical course.

A family with neurofibromatosis is reported in which the proband was an infant in whom the diagnosis was established at birth. In this case, the presenting symptom was a large tumor of the tongue and macrocephaly. Cafe-au-lait spots appeared early, as did additional subcutaneous tumors, with skeletal involvement and severe psychomotor retardation. The rapid growth of the tumor, its spread within the mediastinum, neck and oral cavity, led to a strangulating death at one year of age. The disease originates from early embryonic involvement of the neural crest and from tissues derived from its caudal end. It is probably caused by a single pleiotropic gene transmitted as an autosomal dominant trait, with varying expression of the disease in different members of the same family.

Adolescent↗

PubMedDate not supplied

Carcinocythemia. Report of two cases, one simulating a Burkitt lymphoma.

Carcinocythemia is a rare complication of metastatic carcinoma, characterized by the presence of carcinoma cells in the peripheral blood, which may mimic acute leukemia. Two cases are reported in which the patients developed carcinocythemia several years after being treated for carcinoma of the breast. Cytologic examination of peripheral blood smears in both cases showed the presence of numerous large abnormal cells; in one case the cells simulated those of a Burkitt lymphoma. Cytochemical and/or immunologic marker studies ruled out a hematopoietic origin of the malignant cells in both cases and confirmed a diagnosis of carcinocythemia. The rapidly fatal outcome observed in these two cases was in accordance with the poor prognosis usually encountered with this rare phenomenon.

Adenocarcinoma↗

PubMedDate not supplied

Massive atheromatous emboli to both kidneys: a fatal complication following aortic surgery.

A patient with severe and diffuse ulcerative atherosclerotic arterial disease developed acute renal failure and anuria during insertion of an aortobifemoral graft. Postoperative septicemia, with Pseudomonas aeruginosa and Streptococcus fecalis, led to a deterioration in his condition and death. At autopsy the Dacron bifurcation graft showed no sign of infection, but massive atheromatous emboli of recent origin were found in both kidneys. We suggest using an extra-anatomic approach in reconstructive surgery for occlusive disease of the abdominal aorta in patients with ulcerative atheroma.

Acute Kidney Injury↗

PubMedDate not supplied

Cytomegalovirus-infected cells in a pleural effusion from an acquired immunodeficiency syndrome patient. A case report.

Cells with typical cytomegalovirus (CMV) inclusion bodies were found in smears of a pleural effusion from a 51-year-old acquired immunodeficiency syndrome patient. He suffered from severe, generalized CMV infection and Pneumocystis carinii pneumonia complicated by recurrent pneumothorax. CMV infection was proven by a positive immunohistochemical reaction. Cytologic demonstration of CMV-infected cells in a pleural effusion has not been reported before to the best of our knowledge.

AIDS-Related Opportunistic Infections↗