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Biomedical subjects

N Hjorth

Publications and source records attributed to N Hjorth.

At least 91 records · Page 5Linked to original sources

Contact sensitivity to Irgasan DP 300.

Two persons had allergic contact dermatitis caused by Irgasan 0,2% in a deodorant foot-powder and 0,12% in a deodorant stick respectively. Both had positive patch test reactions to Irgasan 2% pet. One patient was further tested with Irgasan 1% pet. and 0,5% pet. She had positive reactions to these dilutions. In a blind half-sided usage test, a soap bar containing 0,5% Irgasan caused mild itching and a percepitble erythema, although the use of this soap was otherwise tolerated for one month. The soap bar without Irgasan caused no reactions. Although primary sensitization from Irgasan toilet soaps has not been reported, a previously sensitized person may react to the use of Irgasan in soaps.

Adult↗

Lauryl ether sulphate dermatitis in Denmark.

Lauryl ether sulphate (LES), a synthetic detergent, may sometimes contain an allergenic impurity, which has given rise to several outbreaks of contact dermatitis. Such an outbreak occurred in Denmark in 1971. All cases diagnosed were confined to one household, while other cases may have passed unnoticed.

Adult↗

B lymphocytes, T lymphocytes and phytohaemagglutinin responsiveness in atopic dermatitis.

The spontaneous binding of sheep erythrocytes to human lymphocytes with the formation of rosettes was used as a measure of thymus-derived lymphocytes and the rosette formation with complement-coated sheep erythrocytes as a measure of bursa-dependent lymphocytes in the peripheral blood of patients with atopic dermatitis. Both percentage proportion and the absolute number of thymus-derived lymphocytes were slightly but significantly reduced. In a few patients with atopic dermatitis the percentage and absolute number of bursa-dependent lymphocytes were increased. However, when all values were considered, no significant differences were demonstrated. The responsiveness of cultured lymphocytes to phytohaemagglutinin was normal when the culture medium contained foetal calf serum. The response of normal lymphocytes was not impaired by serum from patients with atopic dermatitis. However, the response was depressed when atopic dermatitis lymphocytes were cultured in medium containing autologous serum, indication that a partial lymphocyte defect becomes manifest only in the presence of a serum factor, presumably IgE.

Adolescent↗