Biomedical subjects

N Henry

Publications and source records attributed to N Henry.

At least 37 records · Page 2Linked to original sources

PubMed1977

["Milk aflatoxin" and transfer of toxicity].

Diet including 20 p. 100 of lyophilised milk produced by Goat who consumes peanut meals containing 1,530, 79 and 54 microng/kg aflatoxins with 1,136, 64 and 54 microng/kg aflatoxin B1, is given to duckling during 23 days. There is no influence of this diet on growth, feed efficiency and liver or kidney histology. In contrast, direct consummation of Peanut meal, with the highest level of aflatoxins, produces 18 p. 100 mortality and characteristic injuries of aflatoxiocsis.

Aflatoxins↗

PubMed1977

[Diet imbalances and aflatoxicosis].

Generally we know influences of diet's balances or imbalances upon toxicants. Some actions appear with aflatoxins as shown by studies on rat, pig, calf, poultry, turkey and duckling. According to species considered, oral administration of aflatoxins reduces food consummation, Nitrogen balance, respiratory coefficient. Therefore those modifications may be induced by a decrease of foodstuffs ingestion. It has been underlined that hypoproteic diet increases intoxication and diet rich in lipotropic factors decreases it. The greatest number of experiments carried out are concerning vitamins A and D. Authors are recounting their own experimentations upon relationships between Ducklings, aflatoxicosis, retinol consumption and cholecalciferol deficiency. In Duckling, diet deficient in vitamin D increases aflatoxins toxicity. Some relations exist with cytochrome P 450.

Aflatoxins↗

PubMed1977

Pharmacodynamic study of a pyrophtalone: [methyl-2 (piperidino-2 ethyl-1)-1 dihydro 1-4 pyridylidene-4 yl]-2 indanedione 1-3. II. Mechanism of action.

The anti-inflammatory activity of the pyrophtalone derivative, [methyl-2 (piperidino-2 ethyl-1)-1 dihydro 1-4 pyridylidene-4 yl]-2 indanedione 1-3 or PpEtgammaL is not dependent upon adrenal gland stimulation. PpEtgammaL has an inhibitory effect neither on prostaglandin release after biosynthesis nor on prostaglandin synthetase. The reduced prostaglandin production, as result of drug action can be explained by impairment of substrate availability for this enzyme. There are several hypotheses, but according to the present results of our work, the most plausible one is an inhibition of unsaturated fatty acids release from cell membrane lipids.

Adipose Tissue↗

PubMed1977

Pharmacodynamic study of a pyrophtalone: [methyl-2 (piperidino-2 ethyl-1)-1 dihydro 1-4 pyridylidene-4 yl]-2 indanedione 1-3. I. Anti-inflammatory activity.

The anti-inflammatory activity of a pyrophtalone [methyl-2 (piperidino-2 ethyl-1)-1 dihydro 1-4 pyridylidene-4 yl]-2 indanedione 1-3, has been demonstrated with different methods (carrageenan-induced edema of rat's paw, granuloma formation, adjuvant-induced arthritis). The anti-inflammatory potency is lower but sometimes comparable to that of phenylbutazone. Moreover, the acute toxicity and the ulcerogenic effect of the pyropthalone derivative are clearly less marked.

Animals↗

PubMed1976

Growth requirements of san francisco sour dough yeasts and bakers' yeast.

The growth requirements of several yeasts isolated from San Francisco sour dough mother sponges were compared with those of bakers' yeast. The sour dough yeasts studied were one strain of Saccharomyces uvarum, one strain of S. inusitatus, and four strains of S. exiguus. S. inusitatus was the only yeast found to have an amino acid requirement, namely, methionine. All of the yeasts had an absolute requirement for pantothenic acid and a partial requirement for biotin. Inositol was stimulatory to all except bakers' yeast. All strains of S. exiguus required niacin and thiamine. Interestingly, S. inusitatus, the only yeast that required methionine, also needed folic acid. For optimal growth of S. exiguus in a molasses medium, supplementation with thiamine was required.

Journal Article↗

PubMed1975

[Effect of ammonia treatment of peanut meal cake contaminated with A. flavus on nutritional value for the duckling].

Duckling are feeding peanut and meal detoxified or not by ammonia at the level of 25 p. 100. Control group are eating soybean meal at the same level. The raw protein content of diet is the same in each group. Experiment is carried out during four weeks, then duckling are killed. There is no significative difference between peanut meal detoxified and soybean meal relating to growth and food efficiency. Thus body weight is 775 and 764 g on duckling eating soybean meal; 764 and 827 g on duckling with peanut meal detoxified but only 472 and 452 g on birds with diet containing peanut meal not detoxified by NH3. Liver's weight is increased on these subjects. The ratio of liver weight to body weight X 100 is 5,49-4,79 and, respectively, 2,70-3,60 and 3,86-3,56 on duckling with detoxified peanut meal or controls eating soybean meal. Characteristic lesions of aflatoxicosis are developed on duckling consuming peanut meal not detoxified dosing about 285 mug/kg of Aflatoxin B1. Lesions are very slight, but present, on liver and kidney in detoxified peanut meal fed duckling. For kidney's lesions there are no differences between detoxified or not group, duckling eating detoxified peanut meal have absorbed 0,4 mug of Aflatoxin B1 during the eight first days of experiment and 8 to 10 mug during four weeks. These considerations explain light lesions observed and underlines duckling's sensitivity regarding aflatoxicosis.

Aflatoxins↗

PubMed1974