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Biomedical subjects

N Hayabuchi

Publications and source records attributed to N Hayabuchi.

At least 91 records · Page 5Linked to original sources

[Malignant lymphoma of Waldeyer's ring: is lymphography always necessary?].

The role of lymphography for patients with malignant lymphomas involving Waldeyer's ring was retrospectively reviewed. The materials were 97 patients who were treated at Kyushu University Hospital from January, 1966 to December 1982. Lymphography was performed in 72 patients. Abnormal retroperitoneal nodes were detected only in 13 of them (18%). Six of the 7 patients (86%) with gastrointestinal involvement as well as Waldeyer's ring had positive lymphography, whereas only 6 of the 51 patients (12%) without gastrointestinal involvement had such findings. Although there was a significant difference in survival by cervical and inguinal lymph node status, no such discrepancy was seen between 41 stage II patients staged after lymphography and 16 stage II patients staged clinically. All these results suggest that lymphography is not always essential for patients with malignant lymphomas involving Waldeyer's ring.

Adolescent↗

Slow-growing lung cancer in a fixed population sample. Radiologic assessments.

Radiographs generated during 20 years of biennial chest radiography of 107 patients with histologically proven lung cancers were reviewed for radiological evidence of slow-growing lesions. Twenty-nine of 37 solitary circumscribed peripheral masses which doubled in volume in five or more months prior to any therapy were considered slow growing. By these criteria, 7 (17%) of 41 squamous cell carcinomas were slow growing; whereas 22 (42%) of 52 adenocarcinomas grew slowly. There were no slow-growing tumors among the 14 anaplastic carcinomas or cancers of other histological type. The mean doubling time for the seven squamous cell carcinomas was 5.7 months; that for the 22 adenocarcinomas was 13.1 months. The cancers of females tended to grow more slowly than did those of males. There was no appreciable difference between the mean age of the 29 patients with slow-growing lesions and that of the remaining 78. Not only was the majority of cancer in the present study readily detectable by radiographic screening of the chest; patient survival correlated very well with the growth rates of the lesions, including those of seven resected tumors. The survivals of the seven patients with adenocarcinomas whose lesions were resected were no better than those of the remaining adenocarcinoma patients who had no surgical treatment. The results of this study proved that an appreciable percentage of lung cancers do develop slowly, especially adenocarcinomas.

Adenocarcinoma↗

Screening for lung cancer in a fixed population by biennial chest radiography.

All screening radiographs of the chest and other medical records of 107 patients with histologically proved lung cancer in a fixed population were reviewed to assess the efficacy of biennial chest radiography in detecting lung cancer. Radiographic abnormalities caused by tumors were initially detected in 58 patients (54%); the other 49 (46%) were detected radiographically in subsequent examinations. Thirty-six of the 40 solitary tumors were less than or equal to 4.0 cm in diameter when detected. There were no symptoms in 76% of cases, possibly associated with the predominance of peripheral adenocarcinomas. Routine 36 X 43-cm radiographs, postero-anterior stereoscopic and lateral projections, and comparison with previous radiographs facilitated detection of relatively small tumors in asymptomatic patients. The corrected 5-year survival rate from the time of detection was 20%.

Adenocarcinoma↗

Computed tomography of posterior longitudinal ligament ossification: its appearance and diagnostic value with special reference to thoracic lesions.

An earlier review of the lateral chest radiographs of 8,610 Hiroshima and Nagasaki Adult Health Study subjects revealed 48 persons with posterior longitudinal ligament ossification (PLLO) in the thoracic region. Seven additional PLLO cases detected outside that observation period brought the total to 55. Among them, 15 patients with neurological signs and/or the greatest degree of thoracic PLLO were selected for computed tomography (CT) of the spine in the present study. Computed tomography proved extremely valuable in identifying the location, shape, and severity of PLLO. In two cases, CT differentiated some lesions previously regarded to be PLLO as actually due to hypertrophic margins of vertebral bodies. Possible explanations are included for the development of the laminated or tandem type PLLO, and PLLO that is located laterally rather than in midline.

Aged↗

Irradiated meningiomas: a clinical evaluation.

Eighteen cases of intracranial meningioma that received preoperative or postoperative irradiation with 60Cobalt or Linac have been reviewed. Eight patients received preoperative irradiation because their tumours were very large, hypervascular, and surgically not readily accessible. Two angioblastic meningiomas of the haemangiopericytoma type responded well to irradiation and were easily extirpated. One of these developed a local recurrence and metastases to the lungs and liver nine years after surgery. The recurrent intracranial tumour and nodules in the lungs responded well to irradiation. The other six cases of meningiomas of meningothelial, transitional, or haemangioblastoma types, did not improve clinically or radiologically after irradiation. Ten cases received postoperative irradiation because their tumours were only partially removed or were histologically malignant. In all cases irradiation was most effective for recurrent tumours of the haemangiopericytoma type. This study indicates that irradiation is useful in tumours of the haemangiopericytoma type as an adjunct to surgery or for palliation in advanced stages. Irradiation may been effective in supressing recurrences in two cases of other types of meningioma, although the number of cases is too small to allow any definite conclusion.

Adult↗

Japanese encephalitis.

Japanese encephalitis (JE) is an acute encephalomyelitis which is a primary viral encephalitis accompanying a viral infection. Clinically, the patient who either resides in an endemic region or who has been exposed to the viral vector (mosquito) may have symptoms including high fever, headache, and impaired consciousness. JE involves many portions of the supratentorial and infratentorial compartments including the brain stem, hippocampus, thalamus, basal ganglia, and white matter. Classically MR imaging demonstrates the lesions of JE as hyperintense on T2-weighted images and hypointense on T1-weighted images. Hemorrhagic transformations have also been described in JE lesions, with corresponding expected T1 and T2 changes. Differential considerations based on the MRI appearance are somewhat broad, including but not limited to primary viral encephalitis, acute encephalopathy, limbic encephalitis, and acute disseminated encephalomyelitis. The therapy for JE is primarily conservative and supportive since there is no specific treatment for JE, and the disease has a high fatality rate. The prognosis depends on the extent of involvement at primary presentation, and on the autoimmune mechanisms of this disease.

Adult↗

Successful embolization of coronary arteriovenous fistula using an interlocking detachable coil.

Although the efficacy and feasibility of coil embolization of coronary arteriovenous fistulas have been reported, the procedure may be complicated by migration of the coil into peripheral vessels or pulmonary arteries. We report two cases of successful coil embolization of such lesions using an interlocking detachable coil. This system can provide safer and more effective coil embolization in patients with coronary arteriovenous fistula.

Arteriovenous Fistula↗