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Biomedical subjects

N H Stoller

Publications and source records attributed to N H Stoller.

34 records · Page 2Linked to original sources

Rapidly advancing periodontitis in a patient with sarcoidosis. A case report.

A brief review of sarcoidosis is presented. It is a multisystem granulomatous disease of unknown etiology. Typically the sarcoidosis patient manifests depressed T-cell function but has hyperactive B-cells. This case report deals with a 27-year old black female who was diagnosed as having sarcoidosis. Prior to the onset of the disease, radiographs taken of her periodontium revealed incipient alveolar bone loss. Two years after the apparent onset of the sarcoidosis, periapical radiographs manifested advanced destruction of the alveolar bone. In addition to the usual clinical indices, the effect of the patient's serum on cultures of normal PMNs and Actinobacillus actinomycetemcomitans (A. a.) was studied. The serum from this patient inhibited the leukotoxic effect of the (A. a.) organism. A similar effect has been observed in juvenile patients with rapidly advancing periodontitis.

Adult↗

A comparison of a composite restorative material and wire ligation as methods of stabilizing excessively mobile mandibular anterior teeth.

Eighteen patients with mobile mandibular anterior teeth were randomly assigned to one of two treatment groups in order to determine the relative effectiveness of two modalities of temporary stabilization. The two groups were well matched for initial horizontal tooth mobility, age and sex. Patients in Group I had their stabilized in the conventional fashion with extracoronal wire ligation. The Group II subjects' mandibular anterior teeth were acid-etched and then had composite restorative material applied to the lingual, facial and interproximal surfaces. Horizontal tooth mobility utilizing the periodontometer was recorded prior to, immediately after, and then at 1, 3, 6 and 12 months poststabilization. Löe's Gingival Index and the Silness and Löe Plaque Index were recorded for the same time periods. All subjects were instructed in oral hygiene techniques appropriate for splinted teeth. The mobility scores for both Group I and II dropped to significantly lower levels immediately after the splints were placed and then remained relatively unchanged for the next 12 months. There were no statistically significant changes in the gingival or plaque indices throughout the study. Three splints required repairs or adjustments in Group I subjects. Six fractures occurred in Group II subjects.

Acid Etching, Dental↗

Clinical standardization of horizontal tooth mobility.

The clinical measurement of horizontal tooth mobility is discussed on the background of the current theories regarding the pathogenesis of periodontal disease. The common indices which have been designed to measure horizontal tooth mobility are discussed and critiqued. These indices are not sensitive in that they do not discriminate well between small increments in mobility. In addition, many of the indices cannot be utilized for individual teeth on a longitudinally reproducible basis. The preliminary testing of an in vitro model with mobile teeth which was designed to aid the clinician in assessing tooth mobility is described. Results indicate that the clinician may be capable of discriminating between mobilities that are in the 0.1 mm range, with the aid of the model.

Dental Instruments↗

Inter- and intra-examiner variability in scoring supragingival plaque: I. The clinical study.

Twenty-four normal healthy patients were scored for plaque by four examiners with different professional backgrounds and different levels of training. Each patient was examined twice by each examiner according to a predetermined random assignment with the assumption of no change in state. All four examiners scored higher on the second examination and there was no apparent consistent relationship between professional background and level of training in the plaque scoring.

Dental Hygienists↗

The evaluation of tiodonium chloride as an antiplaque and anticaries agent. IV. Effectiveness on plaque and gingivitis in a short-term clinical study.

The purpose of this clinical investigation was to evaluate the effectiveness of 0.3% tiodonium chloride mouthrinse on various plaque and gingivitis indices. Fifty-five subjects were randomly assigned to the tiodonium chloride or placebo mouthrinses. After a prophylaxis on day 1 of the study, the subjects suspended all oral hygiene except for the daily supervised mouthrinsing. Plaque was monitored by thickness, area, and dry weight. All mean plaque scores were significantly lower in the tiodonium chloride group than in the placebo group (P less than 0.01). Gingivitis was assessed by a clinical gingivitis index and by measuring the amount of crevicular fluid. Mean clinical gingivitis scores (GI) did not differ significantly between the two groups; however the mean gingival fluid score was significantly lower in the tiodonium chloride group than in the placebo group (P less than 0.05). No side effects were reported or observed during the study.

Adult↗

Clinical evaluation of the effect of a proteolytic enzyme mouthwash on plaque and gingivitis in young adults.

One hundred and thirty-one young adults were used in a controlled study to determine whether a proteolytic mouthwash produced from B. subtilis could help remove existing plaque, decrease the rate of plaque accumulation or reduce the clinical signs of gingivitis. These subjects were stratified by means of the Gingival Index and the Shaver-Schiff Plaque Index into severe or mild groups. These groups were further divided in a random fashion into treatment and placebo groups. The treatment group rinsed with a proteolytic mouthwash consisting mainly of neutral and alkaline proteases and amylase. A placebo mouthwash was used by the control group. The results of this investigation indicate that there is no statistically significant reduction either in existing plaque or in the rate of plaque accumulation when this proteolytic enzyme mouthwash is used. Furthermore, in the treatment group the degree of gingivitis as measured by the GI was not reduced.

Adolescent↗

An evaluation of clinical tooth mobility measurements.

This study evaluated the reliability and reproducibility of the modified Miller Index of horizontal tooth mobility. Each of three periodontists utilizing the modified Miller Index assessed the horizontal tooth mobility of 50 teeth in five subjects. The same teeth were also evaluated by the periodontometer. The results of these two methods were then compared. It was found that: (1) there were a high positive correlation between the periodontists' (pooled) assessment of clinical tooth mobility and the measurements of the periodontometer, (2) in any given patient the three periodontists (pooled) were highly accurate in their ability to rank teeth in order of their mobility as determined by the periodontometer, and (3) the periodontists (individually) were not as consistent when comparing teeth with the Miller Index across different subjects. The periodontists did not accurately utilize the Miller Index as it was originally described. It appears that the periodontists either ignored the reference to 1 mm in the description of the Miller Index, or they were unable to estimate what constitutes 1 mm of movemnet in the mouth. The periodontists all consistently scored as a 2 degrees mobility a tooth that moved approximately 0.5 mm not 1.0 mm as described by Miller. It is suggested that the modified Miller Index as described here provides an efficacious system for evaluating horizontal tooth mobility. It provides accurate, reproducible mobility scores in clinical studies requiring an estimation of this parameter. However, for individual teeth, when the clinician or researcher is trying to evaluate the effects of therapy on the periodontium and relatively few evaluation are made, the modified Miller Index may not provide the required degree of sensitively.

Adult↗