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Biomedical subjects

N H Kim

Publications and source records attributed to N H Kim.

156 records · Page 9Linked to original sources
PubMed1990

An experimental study on prevention of postlaminectomy scar formation.

In repeat lumbar surgery for failed back syndrome, well organized fibrous scar tissue is often noted, binding together the dura, nerve roots, and paraspinal muscles. An animal experimental study was done to investigate the prevention of scar formation after lumbar laminectomy by using dacron and sodium hyaluronate. The experimental animals consisted of three groups: 1) control group, 2) D group (covering the laminectomy defect with dacron sheet), and 3) H group (covering the laminectomy defect with sodium hyaluronate gel). Animals were sacrificed at varying intervals (3-12 weeks) and the lumbar spines were evaluated with histologic preparations. Scar adhesion to the dura was most significantly suppressed in the D group, followed by the H group and the control group.

Animals↗
PubMed1989

Clinical significance of the immunological tests in rheumatoid arthritis.

Of the many theoretical causes of rheumatoid arthritis(RA), the most widely held theory is the autoimmune mechanism. In order to clarify the clinical significance of the immunological tests in RA, we studied immunoglobulin and complement levels in sera and synovial fluids of 118 RA patients and the following results were obtained. 1) The levels of immunoglobulins were elevated in both serum and synovial fluid and this was more prominent in the seropositive cases than the seronegative ones. 2) The levels of C3 component were decreased in both serum and synovial fluid, while those of C4 were decreased only in synovial fluid. Serum C3 and C4 component levels were more decreased in the seropositive cases than the seronegative ones. 3) The immunoglobulin levels in serum (IgG, IgM and IgA) and synovial fluid (IgG and IgA) and the levels of C3, C4 component in serum were well correlated with the clinical forms of rheumatoid arthritis. 4) The IgA level in serum and IgM level in synovial fluid were more increased in the exacerbated cases than the chronic ones. 5) Serum IgG level was decreased after steroid medication over one month.

Arthritis, Rheumatoid↗
PubMed1987

A microcomputer-based vision system for area measurement.

A vision system for measuring the area of an arbitrarily shaped object is described. The algorithm consists of a gray-level thresholding technique combined with a region correction procedure based on mathematical morphology. All processing steps are carried out on a microcomputer system equipped with a video digitizer. The algorithm has been successfully applied to a number of images of medical interest including skin wounds and various microscopic-scale objects such as cell cross-sections and multicellular tissues. Excellent agreement between results obtained by the automatic method and by using standard mechanical means has been established experimentally. The approach is demonstrated by a number of experimental examples.

Algorithms↗
PubMedDate not supplied

Contrast enhancement pattern and frequency of previously unoperated lumbar discs on MRI.

Enhancement frequency and patterns (linear intradiscal, nodular intradiscal, and peridiscal) of the 210 previously unoperated lumbar discs were evaluated using contrast-enhanced lumbar MRI. They also were compared with morphologic abnormalities (normal, bulging, protruded, and extruded) and signal alteration (high signal on T2-weighted images) of the disc. Image interpretation was decided by the consensus of two musculoskeletal radiologists. Enhancement was observed in 69 (32.6%) discs. The enhancement patterns were either intradiscal, linear of (79.7%) or nodular (10.2%), peridiscal (7.2%), or combined (2.9%). Thirty-five (77.8%) of the 45 herniated discs, 35 (77.8%) were enhanced, whereas 34 (20.6%) of 165 normal-appearing disc were enhanced. Enhancement was observed more frequently in discs with high signal intensity zones (P < 0.05). In the six patients with enhanced discs, surgery revealed granulation tissue in three extruded discs, two protruded discs, and one bulging disc. The authors believe that contrast enhancements are frequent in herniated discs and are not infrequent in normal-appearing discs. The understanding of various enhancement patterns may help in the interpretation of lumbar spine MRI.

Adolescent↗