Search PubMed⌕ Search

Biomedical subjects

N H Cox

Publications and source records attributed to N H Cox.

At least 37 records · Page 2Linked to original sources
PubMed2002

Guidelines for the management of lichen sclerosus.

These guidelines for the management of lichen sclerosus have been prepared for dermatologists on behalf of the British Association of Dermatologists. They present evidence-based guidance for treatment, with identification of the strength of evidence available at the time of preparation of the guidelines, and a brief overview of epidemiological aspects, diagnosis and investigation.

Evidence-Based Medicine↗
PubMed2002

UK guidelines for the management of cutaneous melanoma.

These guidelines for management of cutaneous melanoma present evidence-based guidance for treatment, with identification of the strength of evidence available at the time of preparation of the guidelines, and a brief overview of epidemiological aspects, diagnosis and investigation. To reflect the collaborative process for the UK, they are subject to dual publication in the British Journal of Dermatology and the British Journal of Plastic Surgery.

Biopsy↗
PubMed2001

Acute oedema blisters: a report of 13 cases.

BACKGROUND: The development of bullae accompanying acute oedema is a commonly observed clinical sign but has been rarely reported in the literature. OBJECTIVES: To document the clinical features and increase awareness of this entity. METHODS: Retrospective case note review of 13 inpatient consultation cases seen in two dermatology departments. RESULTS: Oedema blisters appear to be related to the speed of development rather than the degree of oedema, and respond rapidly to the reduction of the underlying oedema. CONCLUSIONS: Recognition of oedema blisters is important as they respond quickly and completely to treatment of the underlying oedema.

Acute Disease↗
PubMed2001

The incidence of hydroxyethyl starch-associated pruritus.

BACKGROUND: Pruritus due to hydroxyethyl starch (HES) is reported with a very variable frequency but appears to be relatively uncommon in the U.K. compared with other European countries. OBJECTIVES: To determine the frequency of HES-related pruritus in patients discharged from intensive care units (ICUs) in two U.K. hospitals. METHODS: A questionnaire survey was given to 253 patients after discharge from ICU. Questions were designed to exclude pre-existing skin disease and other causes of pruritus. RESULTS: One hundred and fifty-nine completed questionnaires were suitable for analysis. Seventeen of 135 (12.6%) subjects who had received HES reported itch, as did one of 24 who had not received HES. There was no apparent relationship between the occurrence of HES-related pruritus and either the surgical indication or the brand or volume of HES infused. CONCLUSIONS: HES-related pruritus is a problem that dermatologists need to recognize; however, its frequency in the U.K., when other causes of itch are excluded, appears to be lower than suggested in some previous reported studies.

Drug Eruptions↗
PubMed2000

Basal cell carcinoma: are early appointments justifiable?

In the U.K., patients with suspected skin tumours are usually referred from a general practitioner to a hospital-based dermatologist for treatment. The urgency of such referrals is currently a topic of political importance. We have studied case record data from 162 patients with basal cell carcinoma (BCC) to establish the relevance of referrals routinely being considered urgent. At presentation, mean tumour size (maximum dimension) was 7. 4 mm (median 10) and mean duration of BCC was 20.5 months (median 12). There was no correlation (all P > 0.05) between tumour size and patient age (r = 0.1325), tumour size and duration (r = 0.4433), or tumour size and interval between referral and hospital consultation (r = 0.0695). If the slow growth rate of the average BCC is assumed to be linear, a reduction in referral interval from the mean value of 10.7 weeks in our patients down to the U.K. government target of 2 weeks would equate to a size difference in BCC of 0.7 mm, which is not therapeutically significant. Individual BCCs with rapid growth or other features of concern may require urgent referral, but evidence from our patients and from other studies is that this is not routinely necessary.

Adult↗
PubMed2000

An evaluation of educational requirements for community nurses treating dermatological patients.

In a questionnaire to community nurses treating dermatological patients, 14 out of 69 (20%) either treated children or gave advice to parents regarding childhood eczema, 35 (51%) treated adult eczema, 11 (16%) treated psoriasis, 55 (80%) treated leg ulcers, and 30 (43%) treated other dermatological problems. Specific questions regarding confidence to treat or educate were analysed in relation to the tasks being performed. All but 15% (8/55) treating leg ulcers were confident about their ability to apply four-layer bandaging. However, 8 out of 11 (72%) respondents treating psoriasis were not confident about their ability to treat scalp scaling, 11 out of 14 (79%) of those treating childhood eczema were not confident about applying body suiting, and 26 out of 36 (72%) of those treating eczema (any age), were not confident about ability to recognize infection as a cause or complication of dermatoses. The favoured educational modalities were visits to the local dermatology department (60/69, 87%), availability of a dermatology Nurse Practitioner or Liaison Nurse, or access to a hospital nurse-run dermatology clinic (both 44/69, 63%), or attendance at courses (36/69, 52%). Community nurses have an important role in treating and educating patients who may not require or be able to attend hospitals for treatment; they will achieve this best by provision of relevant locally based education, with allocation of adequate study time.

Adult↗