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Biomedical subjects

N H Cho

Publications and source records attributed to N H Cho.

At least 73 records · Page 4Linked to original sources
PubMed1989

Spontaneous whole blood platelet aggregation in insulin-dependent diabetes mellitus: an evaluation in an epidemiologic study.

Spontaneous whole blood platelet aggregation (SWBPA) was examined in a case-control study, comparing a consecutive series of IDDM subjects (n = 30) to age, and sex matched controls. Subjects were free of platelet altering medications. Platelet aggregation was measured by the percent fall in single platelet count after 15 minutes of both shaking (SK) and magnetic stirring (ST). IDDM subjects showed a significantly greater percent fall in SK (means = 12.1) and ST (means = 34.0) compared to controls (SK means = 8.4, p less than 0.01; ST means = 24.3, p less than 0.05). Long-term repeat testing on 15 subjects (diabetics and non-diabetics) up to 4 months apart showed a correlation of 0.7 for SK, p less than 0.01 but only 0.4 for ST. In a further series of IDDM subjects (n = 176) those with macrovascular disease (n = 27) showed significantly greater percent fall in SK (p less than 0.05), and ST (p less than 0.05). We conclude that SWBPA is a simple useful epidemiological technique (shaking being more repeatable than stirring) which relates to both diabetes and macrovascular disease.

Adolescent↗
PubMed1989

Large mononuclear cells in seminoma--an immunohistochemical analysis of 21 cases.

Twenty-one cases of seminoma (including testicular seminoma, ovarian dysgerminoma and extragonadal germinoma) were reviewed for the cell types responsible for the production of alpha-fetoprotein (AFP) and human chorionic gonadotropin (HCG). Histologically the cases included seventeen classical seminomas and 4 anaplastic seminomas. The latter had some mononuclear and multinuclear giant cells. All 4 patients with anaplastic seminoma had elevated levels of serum AFP, and each of these cases contained AFP producing tumor cells identified by immunoperoxidase staining. All seminomas of patients with elevated serum levels of HCG were of the classical type but HCG producing tumor cells could not be identified by immunoperoxidase staining. Immunoreactivity to anti-AFP was found in some large mononuclear cells and anaplastic cells. To explain these results, we propose that the large mononuclear cell is a multipotential cell capable of differentiating into a germ cell, yolk sac and embryo, and that the anaplastic seminoma cells might represent a stage on the continuum of cellular differentiation from the large mononuclear cells to germ cells. The multinuclear giant cell does not appear to be essential for the production of either AFP or HCG in seminoma.

Adolescent↗
PubMed1989

Submucosal lymphatic cyst of the stomach--a case report.

A submucosal lymphatic cyst is a thin-walled cyst, lined by flattened lymphatic endothelium, containing thin serous fluid. It rarely causes clinical symptoms, and it is incidentally discovered during fiberoptic panendoscopy or radiologic study in most cases. It is an extremely rare benign tumor of the stomach; however, a submucosal lymphatic cyst should be considered if a pliable and benign submucosal lesion is detected during fiberoptic panendoscopy. We report a case of submucosal lymphatic cyst of the stomach which showed a typical clinical picture. This report is the first case of submucosal lymphatic cyst of the stomach in Korea to the best of our knowledge.

Age Factors↗
PubMed1985

[Analysis--of family-planning in urban low-income brackets based on Daejon and Daegu Cities].

Since the inception of the national family planning program in 1962, the main emphasis has been placed on the provision of contraceptive services and information, education, and communication (IEC) activities through home visits by family planning field workers and through government designated private physicians. This approach has been a powerful management system for the national program, particularly in the rural area. However, new issues in the national family planning program emerged with the subsequent socioeconomic changes since 1962. An increasing number of the rural population began to migrate to the urban area, and, therefore, beginning in the 1970s, more weight had to be given to the family planning service for the urban area; in particular, for those in the low-income brackets. In an effort to increase contraceptive acceptors among the urban low-income people, the government has implemented various special projects for them since 1974, through maximum utilization of community leaders including Tong and Ban Chiefs and mothers' clubs, and family planning workers in their areas. Thus, this paper analyzes the current status of family planning and fertility behavior of urban low-income wives as a part of program evaluation. Also, this paper is based on an analysis of the 1984 Family Planning Survey data, which was conducted in July 1984 and responded to by 600 married women aged 15-44 in the low-income areas of the Daejon and Daegu cities. The survey data revealed that the contraceptive practice rate was 77.0%, which was much higher than 70.3% of the national practice rate in the same year, and the approval rate for the 1 or 2 children of the low-income areas was much higher than that of other urban areas. Based on the results of the analysis, the following recommendations are suggested for the better program implementation: 1) improvement of program management system for recruiting new acceptors in their 20s for birth spacing; 2) development and inducement of innovative incentive schemes and IEC activities for increasing the proportion of the 1 child families; and 3) strengthening the utilization of community resources including mothers' clubs.

Asia↗