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Biomedical subjects

N Gros

Publications and source records attributed to N Gros.

28 records · Page 2Linked to original sources

Evaluation of gait with multichannel electrical stimulation.

Short, intensive multichannel electrical stimulation therapy was evaluated in 14 hemiplegics after stroke or head injury. The stimulation of the peroneal nerve, soleus, quadriceps, hamstring, gluteus maximus, and triceps brachii muscles with individually preprogrammed sequences was applied by surface electrodes at the beginning of gait rehabilitation. The patients started walking with the support of a therapist, gradually increased the walking distance and all reached independent ambulation with a crutch after an average of 14 stimulation sessions. A portable microprocessor six-channel stimulator/stride analyzer enabled the collection of gait parameters and recording of statistical mean values of stride time, gait symmetry, right and left stance times, and their standard deviations. Without additional equipment, several hundred stimulated strides were measured during each stimulation session.

Adolescent↗

Therapeutic effects of multisite electric stimulation of gait in motor-disabled patients.

Therapeutic effects in ten hemiplegic patients and one paraparetic patient treated by multisite electric stimulation of gait were compared with effects in ten hemiplegic patients treated by standard rehabilitation methods after 2.6 months of extensive therapy. Average step length and gait velocity, ground reaction forces and their distribution under both feet, and crutch loading were measured; goniograms of joint angles, kinesiologic gait analysis, and EMG recordings from the main muscles used in ambulation and in standing, were made while patients in both groups walked without stimulation. Quantitative measurements before, during, at the end, and 8.4 months posttherapy were taken based on at least 40 strides per patient. The results for the stimulated group in midtherapy indicated faster recovery rates (3.15 times in step length and 2.25 times in gait velocity) than in the control group, and at the end of therapy the stimulated group had higher improvement levels (2.14 times in step length, 1.42 times in gait velocity, and 1.63 times in kinesiologic gait analysis). The differences between the two groups faded after 8.4 months without treatment, and some kinesiologic deficits reappeared, mostly those in the more distal muscle groups. These findings indicate a need for a simpler orthotic electric stimulation after multisite therapy in several cases. Immediate effects of the six-site stimulation were also considered for orthotic possibilities after the therapy.

Electric Stimulation Therapy↗

[Catalase activity in Paramecium aurelia].

The catalase activity of Paramecium aurelia was determined by the procedure of Sinha after bacteria elimination from culture medium. A significant level of catalase activity was shown, higher than in other cell kinds. The role of catalase activity in Paramecium sensitivity to low doses of ionizing radiations is discuted.

Animals↗

Recent applications of functional electrical stimulation to stroke patients in Ljubljana.

Functional movements can be restored after stroke by portable neuroelectric stimulator controlled by the patient. This field of activity is called functional electrical stimulation (FES). A common example of FES is electric stimulation of the peroneal to prevent dropfoot. A more sophisticated multichannel enables stimulation of more than one paralyzed muscle of the leg. This system is used temporarily to facilitate recovery of muscle function following stroke. Upper extremity FES systems have proven more difficult to develop than lower extremity systems designed to improve walking. A single-channel hand stimulator is available to assist finger movements.

Braces↗

Rigidity in parkinsonism: characteristics and influences of passive exercise and electrical nerve stimulation.

Rigidity was measured during sinusoidal passive movements of the ankle joint in 7 patients with parkinsonism. Velocity-dependent changes were observed, less marked than in spasticity and expressed in a different way in flexor and extensor muscles: a mild decrease in resistive torques at faster stretching of dorsal flexors and an increase in resistance on stretching of plantar flexors. Dorsal flexors also frequently showed shortening reactions. Passive exercises and electrical stimulation of the peroneal nerve resulted in decreased electromyographic responses to stretch, smoother passive movements and in improved voluntary contraction.

Aged↗

Homovanillic acid (HVA) urinary excretion and day/night rhythm of chronic schizophrenic patients. Preliminary observations.

The authors report, as compared to healthy subjects, a higher daily excretion and a higher urinary variations of homovanillic acid (HVA) for schizophrenic chronic paranoid patients (patients with positive symptomatology predominating, CROW,s type I). Inversely, a lower HVA excretion and probably an inversion of the circadian rhythm of urinary HVA were found for schizophrenic chronic undifferentiated patients (patients with negative symptomatology predominating, CROW's type II). These results have to be confirmed by the study of a greater number of patients and the measure, for comparison among themselves, of other precursors and metabolites of monoamines.

Adult↗