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Biomedical subjects

N Furuhashi

Publications and source records attributed to N Furuhashi.

108 records · Page 6Linked to original sources
PubMed1977

Correlation between climacteric symptoms and serum levels of estradiol, progesterone, follicle-stimulating hormone, and luteinizing hormone.

Correlation between the climacteric symptoms and serum levels of estradiol. progesterone, follicle-stimulating hormone (FSH), and luteinizing hormone (LH) was studied in 191 premenopausal and postmenopausal women. Significant correlation was obtained between the climacteric symptoms represented by the menopausal index of Kupperman and associates and serum levels of estradiol as well as LH in a subgroup of the premenopausal women, ages 35 to 39 years. The symptoms were shown to be significantly related in serum levels of LH and inversely related to estradiol. These results confirmed that climacteric symptoms, at least in premenopausal women 35 to 39 years of age, could result from a low output of ovarian estrogen and a high production of pituitary gonadotropin.

Adult↗
PubMed1977

Changes of hypophysio-ovarian endocrinological function by aging in woman.

Serum estradiol, progesterone, LH and FSH were concomitantly measured by radioimmunoassay in pre- and post-menopausal women in an attempt to study hormonal changes occurring in menopause. The level of serum estradiol in post-menopausal women was maintained at the same level as in pre-menopausal stage within one year after menopause and thereafter began to decrease to the senile minimal level. On the other hand, the mean serum levels of FSH and LH were elevated gradually after menopause. At the conclusion of this study, it was suggested that the key point of the mechanism of menopause may exist not only in the depletion of ovarian function but in the change of the regulatory mechanism of LH and FSH secretion by aging.

Adult↗
PubMed1977

Acute effects of intravenous infusion of conjugated estrogen on serum levels of LH and FSH in post-menopausal and castrated women.

In order to quantify the changes of feed-back effect of estrogen on the release of pituitary gonadotropin which is regulated by the hypothalamic-pituitary-ovarian system, the responses of LH and FSH to the intravenous infusion of 20 mg of conjugated estrogen were studied in 49 post-menopausal and 20 castrated women. In the group of women within 1 year after menopause, serum LH levels were elevated following the infusion of the conjugated estrogen. The responses of serum LH and FSH levels were different between post-menopausal and castrated women. The data indicated that the difference between the two groups was probably due to the difference of secrection patterns of the gonadotropins in post-menopausal and castrated women.

Adult↗
PubMed1977

[Congenital arteriovenous malformation of the extracranial region--report of a case with review of literatures (author's transl)].

Congenital arteriovenous malformation of the extracranial region is rare. The case presented here is a woman aged 29. She gave a history of swelling of the scalp at the left temporat region and noticed a rhythmic pulsating noise in the left ear of five mon ths duration, especially when she placed that side of her head against a pillow. Physical examination revealed a pulsating compressible tumor mass measuring 10 cmx8cm in the left temporal area of the head. There was a bruit synchronous with the pulse and an associated thrill over the mass. A left external carotid angiogram demonstrated that the deep temporat branches of the marked dilated internal maxillary artery as well as the branch of the superficial temporal artery fed the arteriovenous malformation at the extracranial region. Venous drainage to the superficial temporal vein and the maxillary vein were present. Multiple arteriovenous fistulas and persistent pooling of contrast medium were noted. At operation. At operation, the left external carotid artery was ligated and the malformation was excised. The postoperative course was entirely uncomplicated. The bruit disappeared and she was discharged on the 12th postoperative day. Histologically, the arteriovenous malformation was demonstrated. We reviewed the literatures and discussed the etiology, clinical and roentgraphic findings of the congenital arteriovenous malformation at the extracranial region.

Adult↗
PubMed1976

Difference between effects of conjugated estrogen on neurotics and non-neurotics of climacteric women complaining of menopausal symptoms and its clinical application for their screening.

In order to screen the neurotics and non-neurotics of climacteric women with menopausal symptoms, conjugated estrogen was injected intravenously and the reactions were compared. Menopausal symptoms were represented by Kupperman's menopausal index. After estrogen injection the non-neurotics showed a decrease of the index, i.e., alleviation of the symptoms, while the neurotics showed no change of the index. Taking advantage of this difference, a discriminant function between neurotics and non-neurotics was calculated using, as variables, Kupperman's menopasual indices determined before and after administration of the conjugated estrogen. The calculative screening obtained from this discriminant function yielded consistency with clinical diagnosis in about 94% of the neurotics and about 87% of the non-neurotics, suggesting that this test is of value in the screening of neurotics and non-neurotics in the climacteric women with menopausal symptoms.

Adult↗
PubMed1976

Changes in hypophysio-ovarian endocrinological function of post-menopausal and castrated women.

The serum levels of estradiol, progesterone, LH and FSH were determined by radioimmunoassay in post-menopausal and castrated women and the data obtained at the same periods after menopause and castration were compared. The serum levels of estradiol and progesterone in post-menopausal women within 1 year after menopause were higher than those of castrated women. The result suggested that ovarian function was indeed depressed in the post-menopausal women but was still preserved for 1 to 2 years after menopause. In the post-menopausal women, the levels of serum LH and FSH rose gradually to reach a peak at 1 to 3 years after menopause, when the production of ovarian sex steroid hormones presumably ceased. On the contrary, the serum LH and FSH levels of castrated women began to decrease gradually 4 to 9 years after castration. It is highly suggestive from these findings that a negative feedback mechanism is elicited by ageing.

Aging↗
PubMed1975

A new method for the screening of unidentified complaints syndrome in pre-, mid- and post-menopausal women.

A new simple test for the screening of pre-, mid- and post-menopausal women with unidentified complaints overlaid by psychiatric disorders has been devised. This test is performed by intravenous injection of conjugated estrogen and by comparing Kupperman's menopausal indices before and after the injection. That is, the discriminant function between groups with and without psychiatric abnormalities was obtained from Kupperman's menopausal indices before and after intravenous injection of conjugated estrogen, and from this function was made a calculative differential diagnosis between the two groups. The calculative diagnosis agreed fairly well with the clinical diagnosis by the psychiatrist.

Adult↗