[The principles of formulating a diagnosis].
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Biomedical subjects
Publications and source records attributed to N F Siliaeva.
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It is suggested that combined therapy of acute destructive pancreatitis should allow for multiprofile visceral pathology induced by pancreatogenic endotoxicosis and intoxication due to secondary purulent infection.
Basic aspects of the biopsy-sectional course are listed: knowledge of the structure, tasks, juridical status of the pathology service; clinico-anatomical analysis during necropsy; principles of the pathology diagnosis and clinico-anatomical epicrisis; visual presentation of the biopsy and operation material, including urgent biopsies; participation of students in the city clinico-anatomical conferences; lectures about medical deontology and physician errors.
The eyes of 214 foetuses and newborns and 3 children of the 1st year of life dying from asphyxia, skull trauma during the delivery, perinatal infections, chromosomal diseases and newborn haemolytic disease were studied morphologically. Main pathogenetic factors of the premature infant retinopathy are presented. The results of the study indicate that the eye is involved in the pathologic process in various pathology of the perinatal period this implying the necessity of the eye morphological study in those dying perinatally and routine ophthalmologic examination of newborns.
The paper analyses results of pathomorphologic studies of eyes of 28 fetuses and newborns died from multiple malformations due to the Patau (trisomy 13) syndrome. Ocular malformations were recorded in 25 observations (89%). The most frequent and typical ocular malformations in this syndrome were microphthalmia, typical colobomas of the uveal tract, dysplasia of the retina, persistence and hyperplasia of the primary vitreous body, cataract and luxation of the lens.
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Pathomorphologic examinations of 74 preterm fetuses and newborns evidenced that retinopathy of preterm infants occurred in 33.7 percent of these. The development of retinopathy starts in utero. The leading factors in the pathogenesis of this condition are too early untimely delivery and chronic intrauterine hypoxia due to various diseases of the mother and fetal and pregnancy-associated abnormalities.
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One case of a nephropathic variant of primary amyloidosis is described. Genetic or familial genesis of the disease is considered on the basis of anamnesis.
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