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Biomedical subjects

N F Kan'shina

Publications and source records attributed to N F Kan'shina.

At least 19 recordsLinked to original sources
PubMed1991

[Clinico-anatomic manifestations of intestinal involvement in shock].

The possibility of the intestinal involvement in various forms of shock is discussed on the basis of literature data. The intestine is recognized as "a target- organ" in shock together with kidneys and lungs. Microcirculatory disturbances in the intestinal wall result in the decrease of the intestinal epithelium protective function with the development of endotoxemia and aggravation of shock. The consequence of these disturbances is the development of hemorrhages, acute ulcers or large foci of mucous membrane necrosis: clinically this is manifested in intestinal hemorrhages, abdominal pains and dynamic ileus.

Humans↗
PubMed1990

[The most important prospects and tasks in improving the postgraduate instruction of pathologists under perestroika].

It is suggested to reorganize the postgraduate training of pathologists by improving the technical basis of pathology chairs in accordance with modern achievements of medicine and state examinations requirements. The postgraduate training should be continuous and be realized by a self-education and pathologist participation in special courses and teaching cycles with subsequent qualification examination for the 2nd, 1st and highest category (after 5, 7 and 10 years, respectively).

Certification↗
PubMed1990

[The shaping of the clinical anatomical thinking of the pathological anatomist in a specialization lecture cycle in an institute for physician advanced training].

The directions of the evolution of clinico-anatomical approach by young pathologists during the specialization in the above institute are summarized. The work of pathologists consists of the disease history reading, making its written summary, autopsy with writing the protocol, histological examination, establishing the pathology diagnosis and epicrisis. All these stages should be an active thinking aiming at the comparison of clinical data with the results of macro- and microscopical examination and literature data.

Autopsy↗
PubMed1990

[Oligomeganephronic renal hypoplasia complicated by glomerulonephritis].

Clinico-anatomical data of a rare condition congenital oligomeganephronic renal hypoplasia with a glomerulonephritis as a complication are available for a 13-year-old girl who died of chronic renal failure. Large aglomerular zones consisting of primitive canaliculi in a loose stroma were observed in kidneys that were decreased in size. The glomeruli were few in number, some of them of a large size (2-2.5-fold), firmly attached to the capsule, with pronounced extracapillary proliferation.

Adolescent↗
PubMed1989

[Significance of bacterial shock to thanatogenesis in peritonitis].

Fifty-three section examinations of peritonitis with a history of 1 to 30 days were performed to microscopically study viscera and their microcirculatory bed. They revealed microcirculatory disturbances and their consequences that were characteristic of shock. They were most of all pronounced in the kidneys and lungs. The kidneys showed blood dumping with cortical ischemia, which was accompanied with dystrophic changes in the proximal nephroepithelium or focal acute renal failure (ARF) in half the cases. Seven cases displayed advanced ARF of over 8-10-day history with regeneration in the damaged tubules. There were pulmonary microcirculatory disturbances in 27 cases, 10 of them having clinical signs of the "shock" lung, i.e. dys- and atelectases, alveolar bleedings, hyalin membranes, which might be a cause of acute respiratory failure.

Acute Disease↗
PubMed1989

[Respiratory insufficiency due to hyaline pneumopathy after shock].

A case of the shock lung with numerous hyalin membranes is described in a 19-year-old woman after the delivery with a consequent acute respiratory failure. Bacterial shock, acute respiratory disease, possible embolism with amniotic fluid in combination with hypercoagulation typical for pregnancy are named among the causes of the shock lung development. A partial resolution and marked organization of the hyalin membranes are observed.

Acute Disease↗
PubMed1987

[Clinical, morphological and pathogenetic characteristics of combined myocardial infarct of the right and left ventricles].

Proceeding from clinicomorphological correlations in 63 patients with combined right and left ventricular myocardial infarction and in 92 patients with isolated left ventricular myocardial infarction some features of heart coronary pathology that contributed to the formation of a process of different site in the right and left ventricles were revealed. A hypothesis of variants of the pathogenesis of myocardial infarction of the anterior and posterior free walls of the right ventricle was discussed.

Adult↗
PubMed1987

[Experience with the postgraduate training of pathologo-anatomists at the Novokuznets Institute for the Advanced Training of Physicians].

The authors report the experience in training clinical anatomists gained at the Chair of General Clinical Pathology (Pathoanatomy) in the Novokuznetsk Institute for Advanced Medical Training. Altogether 366 specialists in clinical pathology have been trained for the 10-year period (1976-1985). Problems of composing the curricula for the training cycles and their contents are discussed. The significance of such institutes for advanced training of those who specialize in pathoanatomy is emphasized.

Curriculum↗
PubMed1986

[Pathomorphology of eclampsia].

Pathomorphology of eclampsia is reviewed on the basis of literature data and it is noted that the problem has been studied insufficiently. Morphological features of eclampsia are subdivided into two groups; changes in the microcirculatory bed, that are generalized and undergo the following stages: spasm----wall swelling or necrosis----microthrombosis; and postischemic organ changes, such as dystrophy, necroses and hemorrhages. The role of disseminated intravascular coagulation syndrome is discussed in the development of some clinico-morphological features of eclampsia.

Brain↗
PubMed1986

[Intravital diagnosis of Niemann-Pick disease in an adult].

An observation of the Niemann-Pick disease in a male of 53 is described. The disease developed latently, acute clinical symptoms were provoked by spontaneous rupture of the spleen containing numerous "accumulation" Pick cells. Diagnosis was established after histological examination of the operatively removed spleen.

Humans↗
PubMed1984

[Local tumor-like amyloidosis of the lungs].

Local tumour-like lung amyloidosis (LTLA) in a woman of 58 is presented. The disease was not diagnosed clinically. Multiple, well delineated tumour-like, macro- and micronodular foci of amyloidosis were found in the lung at necropsy. The peculiarity of this case is the combination of LTLA with hematogenously disseminated tuberculosis.

Amyloid↗
PubMed1983

[Pathomorphological changes in the kidneys in acute intestinal infections in children].

Morphological lesions of the kidneys in 59 autopsy observations of acute intestinal infections in children were studied. The greatest disorders were found in patients with the toxico-septic form of intestinal infections complicated by the development of bacterial shock. Impairments of the microcirculatory hemodynamics accompanied by dystrophic and necrotic changes in the epithelium of the tubules underlie renal lesions. These changes directly depend on the duration of bacterial shock. With a protracted course of bacterial shock acute renal insufficiency develops. In other forms of the disease renal lesions are insignificant and do not constitute a serious part of tanatogenesis.

Acute Disease↗
PubMed1983

[Organ pathology of bacterial shock].

On the basis of histological and histochemical examinations of 100 postmortem observations of bacterial shock, 4 stages of disorders in the microcirculatory bed and in cell elements of organs in this complication are distinguished. The hemodynamic stage consists in redistribution of the blood flow, alternation of spasm and paresis, and vascular dystonia. In the stage of hemorheological disorders congestion is substituted by stasis, sludging of erythrocytes due to pachyemia. As a result of increased permeability of vessel walls, interstitial edema and early changes of parenchymatous cells of organs occur at the enzymatic level. The addition of DIBC syndrome leads to deeper ischemia of organs and formation of necroses, hemorrhages, acute ulcers. As a consequence, organ insufficiency (adrenal, renal, respiratory) develops.

Adolescent↗