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Biomedical subjects

N F Jones

Publications and source records attributed to N F Jones.

At least 127 records · Page 7Linked to original sources

Exploring schizophrenic thinking in older adolescents with the WAIS, Rorschach and WIST.

Literature that addresses the diagnosis of mental disorder in adolescents strongly suggests that it may not be possible to do so. Schizophrenic thinking, in particular, has been seen as generally characteristic of adolescents. Making judgments of specific responses from the Rorschach, the WAIS, and the WIST, 10 expert clinicians were able to make judgments with regard to 12 adolescents in the 16-19 age range that were surprisingly accurate in discriminating among schizophrenics, nonschizophrenic hospitalized adolescents, and a normal control group. Results indicate that schizophrenic thinking is not necessarily characteristic of adolescents and that information from the WIST may be helpful in identifying schizophrenic adolescents.

Adolescent↗

Effect of radiocontrast media on kidneys of patients with renal disease.

A prospective study was undertaken of 15 patients with impaired renal function undergoing x-ray procedures entailing the use of contrast material to see whether any deterioration in renal function resulted. Patients with diabetes or myelomatosis were excluded. Detailed observations were made during three days before and after the x-ray procedure to detect any change in factors such as fluid state, drug treatment, infection, or diet which might have affected renal function. No significant changes occurred in endogenous creatinine and 51Cr-EDTA clearances, or in plasma creatinine and urea concentrations after the x-ray procedures. Furthermore, there was no change in urinary activity of N-acetyl-beta-D-glucosaminidase, which is a highly sensitive indicator of renal parenchymal damage. Provided that fluid depletion and multiple x-ray procedures with radiocontrast material in rapid sequence are avoided, these procedures do not appear to affect renal function adversely, even when renal disease is advanced.

Acetylglucosaminidase↗

Leucocyte ATP and renal failure.

1. We have measured adenosine 5'-triphosphate (ATP) levels in isolated leucocyte suspensions from patients with renal failure. 2. Leucocyte ATP is reduced in these patients, unlike erythrocyte ATP which is known to be elevated in uraemia. 3. The relevance of reduced leucocyte ATP to the abnormalities of cation transport and cell function which occur in uraemia is discussed.

Acute Kidney Injury↗

Bender-Gestalt performance and recall in an asthmatic sample.

In a sample of intractable adult asthmatics, the prevalence of Bender-Gestalt signs suggestive of neuropsychological problems was documented. Sixty-five per cent of the sample was found to have equivocal or definite Bender-Gestalt signs suggestive of cerebral dysfunction. A clear majority of the asthmatics manifested definite signs of memory impairment when they were asked to recall the Bender designs. The study provides the first documentation of the neuropsychological sequelae of asthma in adults.

Adult↗

Levels of psychological experience in asthma: general and illness-specific concomitants of panic-fear personality.

Coping styles in asthma indexed by a Panic-Fear personality measure are known to influence physicians' medical decisions and long-term treatment outcome. Unusually High or Low Panic-Fear personality styles are maladaptive, the former characterized by anxious, helpless dependency and the latter by an extreme counterphobic independence. In this study (N = 90), the psychological experiences among Panic-Fear personality groups (LOW, Moderate, and High) of asthma patients are described at three levels of assessment: (1) general personality characteristics; (2) attitudes toward asthma and its treatment; and (3) the subjective symptoms reported during breathing difficulties. Comparisons among the groups delineated the linkages between Panic-Fear personality and more illness-specific attitudes, symptoms, and experiences in asthma. Discussion centered upon how general personality and illness-specific characteristics associated with extreme High and Low Panic-Fear personality may contribute to the psychomaintenance of asthma.

Adolescent↗

Characteristics of alexithymic patients in a chronic respiratory illness population.

Alexithymic characteristics in 100 chronic respiratory illness patients were assessed by means of the Beth Israel Psychosomatic Questionnaire (BIQ). The study was designed to explore the relationship of alexithymia to various demographic variables and three disease categories (asthma, tuberculosis, and chronic obstructive respiratory disease). The BIQ was found to yield a high inter-rater reliability when the interviews were conducted and rated in a systematic manner. Significant relationships were found between alexithymia and age, marital status, and disease categories; however, the latter two relationships appear to some extent to be artifacts of the age differences of the subjects among categories. More research is needed to understand the nature of the relationship between alexithymia and age, but it should also be profitable to examine the relationship of this variable to medical outcome.

Adolescent↗

Anxiety reduction in asthma: four catches to general application.

Anxiety reduction procedures as adjuncts to medical treatment have almost invariably been reported to benefit asthmatic patients in individual case studies. However, the results of more systematically controlled studied are clearly inconsistent. This discrepancy is understandable in view of what is now known about anxiety in asthma. Four catches, each based on what has been reported about the roles and forms of anxiety in asthma, are presented. Each catch argues against general, across-the-board application of anxiety reduction procedures in asthma. Careful evaluation leading to more problem-oriented treatment is needed in view of the different roles of anxiety in asthma.

Adaptation, Psychological↗

Reversible renal failure in malignant hypertension.

Acute renal failure requiring dialysis to sustain life may be due to malignant hypertension. If the blood pressure is controlled during a period of dialysis, then it is possible that the renal lesions may heal, with some recovery of renal function. This report describes eight patients with acute renal failure due to malignant hypertension who required temporary dialysis. In all eight cases adequate control of blood pressure was achieved and all recovered renal function such that dialysis could be discontinued. The longest period of follow-up was five years, and one patient achieved a creatinine clearance of 23 ml/min. Renal histology, available in five cases, showed changes of malignant hypertension only, with no evidence of other renal lesions. A review of the literature is presented and the potentially reversible nature of acute oliguric renal failure due to malignant hypertension is emphasized.

Acute Kidney Injury↗

Psychological contributions to chronicity in asthma: patient response styles influencing medical treatment and its outcome.

Research is reviewed relating to two aspects of response styles among asthmatic patients, neither of which is a mere derivative of the patient's medical condition. One aspect, indexed by panic-fear symptomatology, appears to be associated with the level of attention directed at breathing difficulties, ranging from symptom disregard (low panic-fear symptomatology) to symptom vigilance (high panic-fear symptomatology). A second aspect, indexed by a derived personality dimension, appears to be associated with the quality of the patient's reactions to acknowledged breathing difficulties, ranging from extreme independence (low panic-fear personality) to helpless and ineffective dependency (high panic-fear personality). Simply, these aspects of patient response styles refer both to the attention directed toward breathing difficulties and to the quality of the patient's reactions in response to acknowledged breathing difficulties. Their importance derives from 1) their interaction with the severity of asthma to influence medical decisions about the intensity of prescribed medications and length of hospitalization during medical treatment and 2) their effect on long-term medical outcome. Awareness of these two aspects of patient response styles should enable differential approaches to be adopted by physicians seeking to counteract psychological contributions to chronicity in asthma.

Asthma↗

Psychosexual aspects of the panic-fear personality types in asthma.

Numerous earlier studies have demonstrated the close relationship between MMPI Panic-Fear categories and various medical outcome measures in asthma. The present study relates MMPI Panic-Fear categories to psychosexual development. Specifically, High Panic-Fear patients demonstrate oral preoccupations, Low Panic-Fear patients demonstrate anal preoccupations, while Moderate Panic-Fear patients do not demonstrate pre-Oedipal preoccupations. Thus, MMPI Panic-Fear categories, useful in predicting medical outcome measures, have now been related to developmental levels, with the explanatory power of developmental concepts as well as their implications for psychological treatment.

Adolescent↗

N-acetyl-beta-D-glucosaminidase: A new approach to the screening of hypertensive patients for renal disease.

Urinary activity of the enzyme, N-acetyl-beta-D-glucosaminidase (N.A.G.) was examined as a screening test for renal disease in patients with hypertension. Renal disease was present in 64% of patients with increased N.A.G., compared with only 14% of patients with normal N.A.G. The measurement of N.A.G. is cheap and convenient and this simple test warrants further assessment in hypertension as a guide to the need for further investigation.

Acetylglucosamine↗