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Biomedical subjects

N E Marcon

Publications and source records attributed to N E Marcon.

29 records · Page 2Linked to original sources
PubMed1993

Injection therapy for colonic diverticular bleeding. A case study.

We report a successful colonoscopic identification of acute massive diverticular bleeding in an elderly patient and successful injection therapy with epinephrine. Colonoscopy is a valuable diagnostic tool in acute lower gastrointestinal (LGI) bleeding when the colon can be adequately visualized. Peridiverticular injection therapy should be considered a safe and effective therapeutic option when the bleeding site can be established.

Acute Disease↗
PubMed1988

Small colonic adenomas with adenocarcinoma. A retrospective analysis.

The purpose of this study is to alert colonoscopists to a relatively high incidence of small colonic adenomas with invasive adenocarcinoma among a group of colonic adenomas with invasive adenocarcinoma removed colonoscopically. Retrospective analysis (1973 to 1983) documented nine such lesions that were 1 cm or smaller, representing 15 percent of all colonic adenomas with invasive adenocarcinoma removed during that period. These lesions had no distinctive gross features and could be easily confused with hyperplastic polyps. It is recommended that all colonic polyps be removed at colonoscopy regardless of their size, because even lesions 1 cm and smaller, with "benign" gross appearance, may harbor invasive adenocarcinoma.

Adenocarcinoma↗
PubMed1988

Omeprazole (20 mg daily) versus cimetidine (1200 mg daily) in duodenal ulcer healing and pain relief.

We conducted a double-blind, randomized, parallel group study in 169 patients with acute duodenal ulcers to compare omeprazole, 20 mg daily, with cimetidine, 600 mg twice daily. After 2 wk, 58% of the omeprazole-treated patients and 46% of the cimetidine-treated patients were completely healed (p = 0.056). After 4 and 6 wk 84% and 88% healed with omeprazole, and 80% and 89% healed with cimetidine (p = NS). After 2 wk, pain was completely gone in 62% of the omeprazole-treated patients versus 46% of the cimetidine-treated patients (p = 0.04). Clinical or laboratory adverse events were reported in 6 (7%) of the omeprazole-treated patients and 11 (13%) of the cimetidine-treated patients (p = NS). An adverse event caused withdrawal of 1 patient on omeprazole (anxiety and depression) and 2 patients on cimetidine (diarrhea and fall in hemoglobin). We conclude that omeprazole (20 mg daily) resulted in a trend toward more rapid ulcer healing compared with a relatively high dose of cimetidine (600 mg b.i.d.), and was preferred by patients for relief of ulcer pain.

Adult↗
PubMed1984

Pyogenic liver abscess: new concepts of an old disease.

Early recognition of pyogenic liver abscess requires a high index of suspicion. The abrupt onset of hectic fevers and jaundice is rarely seen today; instead, an insidious progression of malaise, abdominal pain, and night sweats is more common. Biliary tract disease is the most frequent underlying disorder. An elevated alkaline phosphatase is a useful clue to the condition, but diagnosis depends on imaging of an abscess cavity followed by aspiration. Treatment involves antibiotics together with drainage, which can often be performed successfully by a nonsurgical percutaneous approach. However, prognosis continues to be poor unless the diagnosis is made promptly.

Alkaline Phosphatase↗
PubMedDate not supplied

The endoscopic management of esophageal cancer.

Cancer of the esophagus is a tumor that, at diagnosis, is often advanced and not curable. The traditional treatment for cancer of the esophagus is still surgery. Assessment of palliative treatments including radiation, YAG laser, photodynamic therapy, prosthesis is done.

Combined Modality Therapy↗
PubMedDate not supplied

Photodynamic therapy and cancer of the esophagus.

Esophageal cancer is a tumor that, at diagnosis, is often advanced and not curable. In patients with good operative risk, surgery is still considered the ideal treatment. As many patients are elderly and have complicating serious medical conditions which preclude major resective surgery, endoscopic treatment (endoscopic oncology) has become a recent alternative. The endoscopic approach includes dilation, thermal destruction with Bicap probes, Nd. Yag laser, injection therapy, photodynamic therapy (PDT) and prostheses. This work is focused on photodynamic therapy which is safe but continues to be an experimental treatment. Its role in gastrointestinal malignancies is evolving. Currently the best results are to be expected in early lesions where the treatment could be curative.

Aged↗