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Biomedical subjects

N E Ebbehøj

Publications and source records attributed to N E Ebbehøj.

10 recordsLinked to original sources
PubMed2005

Molds in floor dust, building-related symptoms, and lung function among male and female schoolteachers.

UNLABELLED: Five hundred and twenty-two teachers from 15 public schools, eight 'water-damaged' schools, and seven 'non-damaged' schools with no visible water damage were included in a cross-sectional design. Mold growth was assessed by recording the amount of dust on the floor and in the air in classrooms and the content of a number of mold species in the dust (CFU/g dust). The evaluation of health symptoms included symptoms recorded by questionnaire and spirometry, bronchial challenge, and CO-diffusion capacity. Nasal lavage fluid was analyzed for IL-8 and ECP. Personal and psychosocial factors were included as confounders. In this study population mucus membrane irritation symptoms (MMI) and general symptoms were reported more frequently by women than by men with odds ratios ranging from 1.4 to 2.1. Women's reports of symptoms from mucous membranes and skin and general symptoms were positively associated with mold exposure. Odds ratio for 'difficult to concentrate' after adjustment for confounders was 11.2 (1.4-90.1, 95% CI) at high levels of mold exposure. None of the lung function tests performed in this study were associated with mold exposure, to the 'water damaged' vs. 'non-damaged' classification, or to the symptoms reported. IL-8 and ECP were not associated either. PRACTICAL IMPLICATIONS: Psychosocial and personal reasons dominate in MMI and general symptoms. Headache and difficulties to concentrate associated with indoor mold exposure, mainly for women. No lung function impairment associated with indoor mold exposure.

Adult↗
PubMed2004

An observation instrument for the description and evaluation of patient transfer technique.

The aim of the present study was to evaluate the reliability and validity of an observation instrument for patient transfer. The instrument, which consisted of 23 items, was evaluated on five different patient transfer tasks. A weighted score was included to evaluate the performed transfer technique. Four observers were selected for the assessment of instrument intra- and inter-observer reliability. Instrument validity was evaluated by testing whether the instrument could detect a difference between use of a self-chosen and a recommended transfer technique. Furthermore, calculated compression values at L4-L5 were compared with the weighted score for the different transfer technique situations. Eleven items were reliable. Nine items deserve further attention and three items were not reliable. The weighted score was significantly higher for the recommended transfer technique situations (p < 0.01) and an association between the weighted score and the calculated compression values was observed (r = -0.589).

Back↗
PubMed2002

Building-related symptoms and molds: a two-step intervention study.

AIMS: To evaluate the relation between mold growth and symptoms in an intervention study design. METHODS: The building was examined by a walk-through and microbiological testing from surfaces and ventilation canals before and after each of two steps of the renovation. The examination program for the 25 employees comprised questionnaire, clinical examination, 2-week peak-flow monitoring, and blood samples, and in six persons also a bronchial challenge. RESULTS: Initially the building had severe moisture problems with growth of Trichoderma and Phoma as dominating microfungi. The total number of symptoms from a nine-item building-related symptom score was 66%, peak-flow variability was 20%. After the first renovation, no visible mold growth was seen, but samples showed that the building was still contaminated. Symptoms decreased to 33%. After further cleaning the mold levels decreased on surfaces, and the number of symptoms decreased to 4%. Mean peak-flow variability fell to 15%. DISCUSSION: In a poorly maintained building with moisture problems and mold growth, the staff had a number of irritative and general symptoms. The first renovation eradicated most visible signs of molds and gave a decreased number of symptoms. The second renovation sufficiently cleaned the building, and the rate of symptoms and peak-flow variability fell to normal levels. A thorough cleaning after renovation seems necessary for the eradication of symptoms.

Air Pollution, Indoor↗
PubMed2001

[Gastrointestinal decontamination. Use in non-drug poisoning].

AIM: To assess whether Danish doctors use gastrointestinal decontamination (GID) in non-drug poisoning in accordance with recommendations for restricted application. METHOD: Doctors telephoning the Danish Poisons Information Centre about non-drug exposures were surveyed prospectively. The doctor's intention to treat, the age and sex of the patient, and information about poison, amount and time since exposure, were assessed. RESULTS: Of the 138 telephone calls, 64% concerned children below 5 years of age and 24% patients above 15 years of age. The risk was estimated as insignificant in 63%, minor in 30%, significant in 6% and severe in only 1%. The insignificant risk was found mainly in children and the severe risk solely in those above 15 years of age. GID was proposed in 33% with the highest frequency in children with minor or insignificant risks, and the time since exposure did not influence the frequency of GID. Charcoal was not proposed. CONCLUSION: It is clear from this small sample that Danish doctors tend to use GID more often than is recommended. Activated charcoal was apparently not used. GID was in most cases used in children with insignificant and minor risks, where it is likely to do more harm than good.

Adult↗
PubMed2001

Risk assessment by physicians and by the poison center: are nondrug exposures handled too actively?

BACKGROUND: The study was intended to evaluate the possible impact of poison center advice on physicians' treatment and referral of nondrug exposures. METHODS: Doctors seeking advice on nondrug poisoning were asked for their management plan before any recommendations were given. The proportions of cases in different treatment and referral categories were compared to the poison center recommendations. Rate ratios were used as effect measure. RESULTS: A total of 175 cases were included in the study. For 90% of these, the exposure was estimated by the poison center to be of no or minor risk. The inquiring physicians had intended to treat 43 more cases than the poison center recommended, rate ratios: 1.6 (95% CI: 1.3-2.0). The most marked difference wasfor treatment by gastrointestinal decontamination, rate ratios: 5.0 (95% CI: 2.5-9.8). For referral, 42 more cases would have been observed in a stationary hospital unit, rate ratios: 2.3 (95% CI: 1.6-3.3) and 28 excess cases would have been observed in an outpatientfacility, rate ratios: 2.0 (95% CI: 1.3-1.6). A more active attitudefor treatment and referral by the inquirers was independently associated with patients < or =14 years of age, lack of symptoms at presentation, and insignificant exposures. CONCLUSIONS: Doctors seeking advice on the management of nondrug poisoning intended to treat and refer to health care facilities more actively than recommended by the poison center. The tendency was most pronouncedfor children exposed to substances of minor toxicological significance and treatment with gastrointestinal decontamination.

Humans↗
PubMed1998

[Boron poisoning].

Explore the source record for details and available documents.

Boron Compounds↗
PubMed1997

[Zinc chloride smoke pollution. Effects of minimal exposure].

Thirteen patients were exposed to accidental zinc chloride inhalation during an army exercise. Smoke bombs were released in open air. The exposure was modest ranging from "taking a few inhalations" to "5-10 minutes in a house with smoke drifting in through unshuttered windows". Initial symptoms were scanty. All patients received inhalation steroid on admittance followed by i.v. bolus of hydrocortisone. Four patients continued systemic steroid treatment (prednisolone 40 mg with stepwise reduction to zero over four weeks) because exposure was judged significant (> 1 minute of unprotected inhalation). No respiratory symptoms developed within an eight week observation period. However, a gradual decline in pulmonary CO diffusion capacity (to 85% (76-99 of initial capacity) was observed within the first four weeks. It is concluded that a very modest inhalation of zinc chloride smoke may induce prolonged impairment of pulmonary function.

Adult↗
PubMed1996

[Acute arsenic poisoning].

We report three cases of arsenic poisoning in a chemical factory. Three workers were exposed to vinyzene 10,10'-oxydephenarsine and developed mild symptoms of acute poisoning. All patients were treated with dimercaprol, and recovered after a few days. Urine analysis did not show increased arsenic excretion, but this could be due to the large urine samples taken. It is recommended that a urine sample is taken right after admission to hospital and new samples after eight and 16 hours.

Accidents, Occupational↗