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Biomedical subjects

N Don

Publications and source records attributed to N Don.

9 recordsLinked to original sources

Effectiveness of an individualized multidisciplinary programme for managing unsettled infants.

OBJECTIVE: To ascertain the effectiveness of an individualized multidisciplinary residential programme for managing young unsettled infants and whether changes in unsettled behaviour were maintained. METHODS: One hundred and nine clients of a Tresillian residential unit with singleton infants aged less than 20 weeks were studied before, during and after intervention. Mothers completed a 24 h infant activity record prior to admission, during the stay and 1 month after discharge. Intervention consisted of settling techniques, parent education, support and counselling. RESULTS: By day 4 of admission, the mean duration of unsettled (fussing, crying) behaviour had decreased significantly and mean sleeping time and awake/content times both increased significantly (P < 0.001). These changes were maintained 1 month after discharge. Changes in behaviour were particularly marked for very unsettled infants. CONCLUSIONS: In the absence of formal controls, the individualized programme appears effective in managing the behaviour of unsettled infants.

Adult↗

Postnatal depression, anxiety and unsettled infant behaviour.

OBJECTIVE: This study compares maternal mood, marital satisfaction and infant temperament in 128 mothers admitted to the residential care unit of a parentcraft hospital and 58 mothers in a demographically matched group. METHOD: Mothers were recruited from the residential care unit of a parentcraft hospital (Tresillian Family Care Centres) and a comparison group from a private obstetric practice in the same demographic area. Both groups completed self-report questionnaires on depression, anxiety and marital adjustment, while mothers in the residential care group also received a structured diagnostic interview for depression (CIDI). RESULTS: Sixty-two per cent of mothers in the residential care group met diagnostic criteria for a major depressive episode occurring since childbirth and a further 13% met DSM-IV research criteria for minor depression. The residential care group also scored significantly higher on both state and trait anxiety and rated their infants as significantly more temperamentally difficult than did the comparison group. CONCLUSIONS: This study replicates a previous Australian finding of a high incidence of maternal mood disorders in mothers admitted to parentcraft hospitals. Acknowledgement of the close association between maternal mood state and unsettled infant behaviour facilitates an integrated multidisciplinary approach offering appropriate management for both mothers and infants. Residential care units may be ideally suited to provide such early intervention strategies in a non-stigmatizing environment, but provision of adequate staff support, mental health consultation, education and skills in managing mental health problems in these settings is important.

Adult↗

Sialuria: a second case.

A case of sialuria is described in a girl who presented in the neonatal period with hepatosplenomegaly, and who has moderate developmental delay at the age of 2 years. There was massive urinary excretion of free sialic acid (N-acetylneuraminic acid). The clinical, biochemical and ultramicroscopical features were distinct from those described in Salla disease and in infantile sialic acid storage disorder.

Child, Preschool↗

Deletion 15q21.1----q22.1 resulting from a paternal insertion into chromosome 5.

A 15 month old boy with an interstitial deletion 15q derived from a paternal insertion (5;15)(q31.3;q21.1q22.1) is described and compared with one other reported case. A beak like nose with hypoplastic nasal alae, a thin upper lip, failure to thrive in infancy with later onset of obesity, and severe mental retardation are features common to both.

Abnormalities, Multiple↗

Two concurrent epidemics of enteroviral meningitis in an obstetric neonatal unit.

A small epidemic of viral infection occurred in a neonatal unit. It involved 11 infants, all of whom recovered. Echovirus 11 was the cause of illness in six infants, coxsackie B3 in four, and one infant had a biphasic illness, due first to echo 11, then to coxsackie B3. The epidemic coincided with a major outbreak of echovirus 11 and a smaller outbreak of coxsackie B3 in the community. Several staff became ill. Five infants were considered to have been infected by perinatal materno-infant spread, others by cross-infection. The epidemic ended when the nursery was closed.

Australia↗

Fifth day fits: a syndrome of neonatal convulsions.

A new syndrome of neonatal convulsions is described. Ninety cases were documented from one maternity hospital between 1973 and 1977. The appearance of this syndrome increased the annual incidence of neonatal convulsions from fewer than 3 to more than 16 per 1000 live births. Fits began on about the fifth day in apparently healthy babies. Investigations and therapeutic trials have not shown the cause. There were no deaths and all babies were discharged from hospital apparently well. The term fifth day fits is suggested with criteria for this diagnosis.

Adolescent↗