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Biomedical subjects

N D Greyson

Publications and source records attributed to N D Greyson.

58 records · Page 4Linked to original sources

A comparison of three radionuclide techniques for measuring blood flow to rat extremities.

A detailed comparison of three radionuclide techniques to estimate blood flow was done in the rat hind limb under reduced, normal and increased blood flow. The techniques compared were the washout of intra-arterial and intra-muscular Xenon-133 and the accumulation of radioactive microspheres in the reference organ technique. There was no significant difference between the three techniques at each of the three flow states. This confirmed that the simpler I.M. Xenon technique is a useful and accurate technique in estimating low blood flow rates in small animals. It was found that the skin puncture had to be sealed after the intra-muscular injection of Xenon to obtain valid results.

Animals↗

Osteochondritis of the hallux sesamoid bones.

The clinical, radiological, and pathological features of six cases of osteochondritis of the metatarsal sesamoids are presented. This condition seems to affect primarily young females. Bone scans are a useful tool in assessing disease in the hallux sesamoid bones. Stress fracture and subsequent repair are postulated as the etiology of osteochondritis of the hallux sesamoid bones. Many of these cases do not respond to conservative management and the affected sesamoid must be surgically removed.

Adult↗

Spontaneous osteonecrosis of the medial tibial plateau.

Spontaneous osteonecrosis (ON) of the medial tibial plateau was diagnosed in 15 elderly patients (21 knees). The onset was characterized by sudden severe medial knee pain, usually with an effusion. Radiographic changes suggestive of ON occurred medial to the weight bearing area of the medial tibial plateau in 9 knees and were normal in 12. The disease entity was documented most clearly by intense radionuclide bone uptake in the medial tibial plateau in all knees. It could be distinguished clinically and radiologically from medial femoral ON, tibial stress fractures and primary osteoarthritis (OA). Tibial ON did not appear to accelerate the development or progression of OA of the knee and most patients were better in less than 1 year.

Aged↗