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Biomedical subjects

N D Goldstuck

Publications and source records attributed to N D Goldstuck.

30 records · Page 2Linked to original sources

The relationship of IUD dimensions to event rates.

The relationship of horizontal-to-vertical ratio (HVR) of 14 commonly used IUDs was compared to medical removal and expulsion rates. A significant positive statistical correlation between IUD HVR and medical removal rate existed. However, no correlation existed between HVR and expulsion. A ratio of about 0.5 for multiparous and 0.7 for nulliparous women less frequently in medical removal of the device. The endometrial cavity length sizes have boundary values on IUD width of 15-18 mm for nulliparae and 18-25 mm for multiparae. The endometrial cavity is thus functionally an isosceles triangle or isosceles trapezoid.

Birth Rate↗

A comparison of the initial pain response following insertion of the Copper 7 and combined Multiload Copper 250-short IUDs.

The immediate postinsertion and 3 minute postinsertion pain response in nulliparous women undergoing insertion of either the Copper 7 (Cu 7) or the Multiload Copper 250-short (ML Cu 250-short) IUD has been studied. 35 women were fitted with a Cu 7 device and 23 with the ML Cu 250-short. The immediate postinsertion pain scores were significantly higher in the ML Cu 250-short group than in the Cu 7 group. There was no significant difference between the 3 minutes postinsertion scores for the 2 groups. The 3 minute pain scores were significantly lower than the immediate pain scores for each individual device group. Immediate postinsertion IUD pain may be related to the presenting diameter and insertional mechanism of the device. This pain is of short duration and after 3 minutes, the level of pain is independent of the type of device which has been inserted. The rapid diminution of pain at 3 minutes postinsertion indicates that the routine use of certain analgesic techniques, e.g., paracervical block before IUD insertion, is not justified. Pain following IUD insertion may provide a useful model for the study of various types of peripheral and centrally acting analgesics.

Chemical Phenomena↗

Pain response following insertion of a Gravigard (Copper-7) intrauterine contraceptive device in nulliparous women.

A total of 33 nulliparous women aged between 18 and 35 have been observed for related symptoms following insertion of an intrauterine contraceptive device. Seventy-five percent suffered some abdominal pain initially but this was reduced to 1% by the end of the week. The symptoms of cramp and backache showed a similar trend. There was no relationship between symptoms and the day of the cycle on which insertion was performed. It is concluded that careful insertion of the Copper-7 in this group of patients is well tolerated irrespective of the day of cycle on which insertion is performed. The initial dynamic response following IUCD insertion may be an additional factor in the assessment of the performance of an individual intrauterine contraceptive device.

Abdomen↗

Post-coital intrauterine device insertion - a further evaluation.

A total of 191 patients have undergone post-coital insertion of an intrauterine contraceptive device up to ten days post-coitus. The majority of patients were nulliparous and underwent insertion of a standard Gravigard [Copper 7] device. The subsequent expulsion and medical removal rates were normal for this group of patients but the non-medical removal rates were higher. There was one possible post-coital contraceptive failure (0.6%) and one pregnancy at six months due to the device exhibiting a failure to conventional contraceptive action.

Coitus↗

The use of a modified copper intrauterine device in nulliparous women with small uterine axial length.

In a preliminary study a highly selected group of 31 nulliparous patients with uterine axial length less than 6 cm underwent 32 insertions of a modified Gravigard device with reduced vertical and horizontal arms. After at least six months of use 26 patients (81%) continued to use this method of contraception. The six patients who discontinued are accounted for as follows: one became pregnant, two expelled the device, two requested removal of their devices because of pain and bleeding, and one device was removed accidentally. There was one further pregnancy at nine months of use. It is concluded that provided that the dimensions of the Gravigard are reduced, it is an acceptable method of contraception in nulliparae with small uterine axial length.

Adolescent↗

The Mark-7 intrauterine sound - an accurate determinant of uterine axial length.

The axial uterine length of 60 nulliparous patients has been measured using a standard Galabin sound and a new flexible disposable sound (Mark-7). In 47 patients the values obtained with the plastic sound were between 0.25 cm to 0.5 cm greater than the values obtained with the metal sound. The flexible plastic sound values are probably larger because this sound is able to follow uterine axial curvature. The element of parallax error which is inherent in using metal sounds is avoided by use of a sliding half-collar at the distal end of the instrument, which can be moved against the cervix allowing fixed measurement. This instrument should be a useful adjunct to intrauterine device research and usage where the relationship of uterine length to device performance is being considered.

Female↗