Production of human albumin solution: a continually developing colloid.
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Biomedical subjects
Publications and source records attributed to N Coker.
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We carried out extensive audiologic, electrophysiologic, and neuropsychologic testing on a young woman who complained that she had difficulty hearing in her educational environment. Conventional audiometric results, including pure-tone, speech, and immittance audiometry, were all within normal limits. The subject performed normally on tests involving the processing of rapidly changing temporal information, interaural time and intensity difference detection, and both absolute and relative sound localization. Early, middle, late and task-related auditory evoked potentials were essentially normal, although some asymmetry was observed in the middle latency (MLR) and late (LVR) responses. There was, however, a consistent left-ear deficit on dichotic sentence identification, on threshold and suprathreshold speech measures in the left sound field when various types of competition were delivered in the right sound field, and on cued-target identification in the left sound field in the presence of multitalker babble. Results suggest a central auditory processing disorder characterized by an asymmetric problem in the processing of binaural, noncoherent signals in auditory space. When auditory space was structured such that the target was directed to the left ear, and the competition to the right ear, unwanted background was less successfully suppressed than when the physical arrangement was reversed.
The effects of both natural and sedated sleep on the auditory steady state evoked potential (SSEP) were evaluated in nine normal-hearing subjects. Both absolute amplitude and phase variability measures were obtained by Fourier analysis of successive samples of the averaged SSEP waveform. Amplitude decreased significantly in the sleeping state but phase variability was not substantially altered. Because it does not seem to be affected by sleep, phase variability of the SSEP is suggested as a potentially useful technique for predicting threshold sensitivity.
A 31-year-old black male experienced severe recurrent urticaria and angioedema during meals. An abnormal sialographic pattern indicated submandibular sialoadenitis, and surgical excision of the gland resulted in complete resolution of the urticaria. This report describes the association of sialoadenitis and urticaria and possible mechanisms involved.
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Attempts have been made to improve noninvasive clinical blood pressure (BP) monitoring by using monitoring sites more easily accessible than the traditional brachium. The purpose of the current study was to evaluate the performance of an automatic, noninvasive BP monitoring instrument that measures BP at the forearm. The only forearm BP monitoring instrument found on the market was the BP/Clinic (CardioAnalysis Systems). Blood pressure and heart rate (HR) measurements from the BP/Clinic were compared with sequentially recorded BPs determined by the auscultatory method and HRs determined by palpation of the radical artery. Accuracy, precision, and failure rates were determined for the BP/Clinic using linear regression, correlation coefficients, and standard error of the estimates. The accuracy and precision of the BP/Clinic approximated those of the standard methods. Systolic BP (r = 0.82) and HR (r = 0.85) correlated more closely with the standard than did diastolic BP (r = 0.75). It appears from this study that the forearm is an acceptable site for clinically useful systemic BP and HR measurements. In addition, the BP/Clinic performed sufficiently easily, accurately, and reliably to be useful for monitoring BP and HR.