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Biomedical subjects

N Cobos Barroso

Publications and source records attributed to N Cobos Barroso.

23 records · Page 2Linked to original sources

[Pulmonary sequestration. Apropos of 10 cases].

Pulmonary sequestration is a congenital anomaly in which an aberrant systemic artery arising from the thoracic or abdominal aorta supplies part of the lung, usually the lower lobes. The sequestrates part of the lung may be anatomically included in the substance of the lobe (intralobar) or may be separate from the other lobes, being contained within its own pleural investment (extralobar). The cases of ten patients with sequestration of the lung seen during a seven-year period are reviewed, with special consideration of their clinical and radiographic findings. Emphasis is made on the differences of our cases with those of the literature: 1) Eighty per cent of the patients had previous symptoms; 2) The intra/extralobar ratio was 1.5/1; 3) All intralobar sequestrations were indifferently localized in left or right lower lobes, and 4) Associated anomalies were present with the same incidence in the two classic forms.

Abnormalities, Multiple↗

[Cystic adenomatoid malformation of the lung (author's transl)].

Four cases of congenital cystic adenomatoid malformation are presented. The age of the patients ranged from 1 day to 7 years. All cases were treated surgically and 3 of them survived. The only death in the group corresponded to the neonatal case. The clinical, radiological and patological features of congenital cystic adenomatoid malformation are also reviewed. Occasionally the clinical manifestations will be hardly noticeable or non existent and the malformation may be diagnosed beyond the neonatal period in the course of a radiological examination performed as routine or because of repeated respiratory infections. Surgery is the treatment of choice. In the group of neonates where the cystic adenomatoid malformation doesn't cause respiratory difficulty the authors feel that it might be advisable to postpone surgery until a later date.

Child↗

[Bird breeder's lung in children].

A case of hypersensitivity pneumonitis due to pigeon-dropping antigens is reported in a 9 year old girl, and compared with other seven previous reports in children. The insidious nature of this disease, as well as the importance of detailed environmental information in children with unexplained respiratory disease are emphasized. In this case, lung function tests showed a classic restrictive ventilatory defect, and a serious obstructive ventilatory defect evidenced in the narrowing of the smaller airways, and a reduction in the forced expiratory flow at small lung volumes. Hypersensitivity pneumonitis is a lung disease that results from sensitization by inhalation of a variety of organic dusts. Patients usually have circulating antibodies against the etiologic agents. Most patients with this disease also have sensitized T-cells to these agents. Long-term exposure can lead to irreversible lung disease. The histopathologic features are chronic interstitial and alveolar inflammation frequently accompanied by a granulomatous response. The most common symptomatic features are fever, chills and dyspnea 4 to 8 hours after exposure. Antibody activity to antigens is detected in the serum of both symptomatic and asymptomatic breeder's lung. Cellular hypersensitivity to antigens is demonstrated "in vitro" with peripheral lymphocyte populations in almost all symptomatic patients.

Airway Obstruction↗