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Biomedical subjects

N Cimolai

Publications and source records attributed to N Cimolai.

At least 73 records · Page 4Linked to original sources
PubMed1991

Osteomyelitis of the pelvis due to Fusobacterium nucleatum.

Anaerobic pelvic osteomyelitis occurs rarely in children. A case of Fusobacterium nucleatum osteomyelitis of the right ilium [correction of ileum] in a child without apparent risk factors is described. This case emphasizes the value of diagnostic aspirates. Therapy with a combination of intravenous and oral clindamycin led to successful resolution of the infection.

Child↗
PubMed1990

Rapid immunoblot method for diagnosis of acute Mycoplasma pneumoniae infection.

A rapid immunoblotting technique based on the IgM response to a major immunogenic protein is described for the diagnosis of Mycoplasma pneumoniae infection. Using results of the complement fixation test as the criterion for diagnosis, the rapid immunoblot method was positive in 95.7% of patients. The sensitivity was reduced to 81.9% if the test was performed on either single sera or acute sera only from serum pairs. Although the few sera that failed to demonstrate a positive IgM response were more likely to be from older patients, there was a consistent IgM response recorded for both younger (less than 20 years) and older (greater than or equal to 20 years) patients.

Antibodies, Bacterial↗
PubMed1990

The epidemiology of beta-haemolytic non-group A streptococci isolated from the throats of children over a one-year period.

The incidence of beta-haemolytic non-Group A streptococci (BHNAS) in the throats of a paediatric population was examined over a 1-year period. There was minimal seasonal fluctuation of Lancefield groups including species and biotypes within Groups C and G streptococci. A trend of increasing incidence with age of Streptococcus anginosus ('Streptococcus milleri') (possessing Groups C and G Lancefield antigens) was evident. A clinical impression of streptococcal pharyngitis was more common in patients with large-colony Groups C or G streptococci isolated from their throats compared with those patients where other BHNAS were isolated. This study is requisite to the planning of case control studies which are required to test the association of BHNAS (especially Groups C and G subgroups) and pharyngitis.

Adolescent↗
PubMed1989

Assessment of the BACTEC NR660 blood culture system for the detection of bacteremia in young children.

The sensitivity of the BACTEC NR660 blood culture system was assessed by using paired bottles of anaerobic (NR7A) and resin-containing aerobic (NR16A) media and conditions and organisms which simulated those found in pediatric practice. Corresponding media (7D and 16B) of the established BACTEC 460 radiometric method served as controls. The performances of the two systems were similar with 50 isolates of 10 aerobic organisms (aerobic medium) and with 21 isolates of 15 strict anaerobes (anaerobic medium).

Bacteria↗
PubMed1989

Mycoplasma pneumoniae associated arthropathy: confirmation of the association by determination of the antipolypeptide IgM response.

The association of Mycoplasma pneumoniae with arthropathy in children and young adults has been established essentially on the basis of complement fixation (CF) serology. Because the CF test may be nonspecific for M. pneumoniae, we have confirmed the association by determination of IgM ELISA and IgM and IgG immunoblotting responses in 2 children. Mycoplasma pneumoniae should be considered in any patient with acute respiratory illness who subsequently develops arthropathy.

Antigens, Bacterial↗
PubMed1988

Culture-amplified immunological detection of Mycoplasma pneumoniae in clinical specimens.

We have employed a monoclonal antibody directed to a Mycoplasma pneumoniae membrane-associated protein antigen in a culture-amplified detection system. Eleven culture-positive sputum specimens were detected significantly more early by the immunoassay. Specimens culture-positive for other probable mycoplasma spp. were negative by this technique.

Antibodies, Monoclonal↗
PubMed1987

Saccharomyces cerevisiae fungemia: case report and review of the literature.

Saccharomyces cerevisiae was isolated on two separate occasions from the blood of a patient with chronic renal failure receiving dialysis. Treatment was complicated by recurrent ventricular tachycardia occurring after both 1 mg and 0.1 mg test doses of amphotericin. We report the unique clinical and microbiological aspects of this patient's management, and review the literature pertinent to this organism.

Humans↗
PubMed1987

Immunological cross-reactivity of a Mycoplasma pneumoniae membrane-associated protein antigen with Mycoplasma genitalium and Acholeplasma laidlawii.

A murine monoclonal antibody, OC2F5, reacts with a Mycoplasma pneumoniae antigen with an approximate Mr of 43,000. This antigen is trypsin and proteinase K sensitive and partitions in the detergent phase of a Triton X-114 solution. The monoclonal antibody cross-reacts with an antigen from both Mycoplasma genitalium and Acholeplasma laidlawii with a similar molecular weight. This cross-reactivity should be considered in the development of M. pneumoniae antigen detection systems based on the use of antibodies directed to this protein antigen.

Acholeplasma laidlawii↗