Search PubMed⌕ Search

Biomedical subjects

N Christen

Publications and source records attributed to N Christen.

8 recordsLinked to original sources
PubMed1996

[The efficacy of radiotherapy in vertebral hemangiomas].

AIM: Assessment of the efficacy of radiation therapy for symptomatic vertebral hemangiomas. PATIENTS AND METHODS: Records of 19 patients who were treated from 1969 to 1988 were retrospectively analyzed. Radiation treatment was given at 2 Gy per fraction to 20 Gy (n = 2), 30 Gy (n = 11), or 40 Gy (n = 6). Improvement of symptoms was chosen to determine the efficacy of the treatment. In addition the lesions were controlled radiographically. RESULTS: Symptomatic improvement was achieved in 17 of 19 patients, remission was complete in 7 patients. No dose-response relationship was observed. The median time to improvement of symptoms was 3 months. The radiographic controls did not correlate with the clinical course. CONCLUSIONS: Radiation therapy is an effective treatment for symptomatic vertebral hemangiomas. The aim of the treatment is to ameliorate clinical symptoms, radiographic improvement is of minor importance.

Adult↗
PubMed1993

[Gynecologic brachytherapy--from low-dose-rate to high-tech].

The transition from low-dose-rate (LDR) brachytherapy to high-dose-rate (HDR) afterloading treatment is in progress in most centres of radiation therapy. First reports of studies comparing HDR and LDR treatment in cervix cancer demonstrate nearly equal local control. In our own investigations on 319 patients with primary irradiated carcinoma of the cervix (125 HDR/194 LDR) we found the following control rates: Stage FIGO I 95.4%/82.9% (HDR versus LDR), stage FIGO II 71.4%/73.7%, stage FIGO III 57.9%/38.5%. The results are not significant. The side effects--scored after EORT/RTOG criteria--showed no significant differences between both therapies for serious radiogenic late effects on intestine, bladder and vagina. The study and findings from the literature confirm the advantage of the HDR-procedure for patient and radiooncologist and for radiation protection showing at least the same results as in the LDR-area. As for radiobiological point of view it is important to consider that the use of fractionation in the HDR-treatment is essential for the sparing of normal tissues and therefore a greater number of small fractionation doses in the brachytherapy should be desirable too. On the other hand the rules, which are true for fractionated percutaneous irradiation therapy (overall treatment time as short as possible to avoid repopulation of tumor cells) should be taken into consideration in combined brachy-teletherapy regime in gynecologic tumors. The first step in this direction may be accelerated regime with a daily application of both treatment procedures. The central blocking of the brachytherapy region from the whole percutaneous treatment target volume should be critically reflected, especially in the case of advanced tumors.

Aged↗
PubMed1978

[Intravenous arteriography with xerography: a non-invasive method for the demonstration of peripheral vessels (author's transl)].

Acceptable arteriograms of the extremities can be obtained by rapid manual injection of contrast into a cubital vein, using a xeroradiographic technique. The indications and value of the method have been demonstrated in 62 examinations. The new technique constitutes a non-invasive arteriographic method suitable for demonstrating limited vascular lesions in the extremities.

Angiography↗
PubMed1977

[Transvenous xero-arteriography of the limbs (author's transl)].

Well-visualised arteriograms of the limbs can be obtained by xeroradiography after rapid manual injection of contrast-medium into an arm vein, as demonstrated in 28 patients. The technique is suitable for the diagnosis of circumscribed vascular lesions. It is simple to do and does not significantly distress the patient.

Adolescent↗
PubMed1977

[Transvenous xerotom-angiography of the pulmonary hilus (author's transl)].

Normal-size lymph-nodes and air-filled bronchi do not contribute significantly to the shadow of the normal hilus. This consists mainly in pulmonary arteries and veins of the upper lobes. Any enlargement beyond the vascular shadow has to be considered as pathologic. Xerotom-angiography following injection of contrast medium into the cubital vein shows the pulmonary vessels near the hilus more clearly. Pulmonary arteries towards the truncus are better shown. This improves the clarity of the hilus. Coincident demonstration of the superior vena cava may show pathologic processes in the upper mediastinum.

Angiography↗