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Biomedical subjects

N Chakir

Publications and source records attributed to N Chakir.

At least 37 records · Page 2Linked to original sources

[Primary intradural extramedullary hydatidosis. Case report and review of the literature].

The authors report a case of cauda equina compression by intradural hydatid cyst. An 18-year-old man presented with paraparesis and sphincter dysfunction. MRI showed an intradural cystic lesion extending from L1 to L2 with low signal intensity on T1 and high signal intensity on T2. The cyst was removed after laminectomy and opening of the dural sac. Histological and parasitic examinations confirmed a diagnosis of hydatid cyst. The patient improved progressively after surgery. The similar 22 cases of intradural extramedullary hydatid disease reported in the literature were reviewed. All spinal areas were involved, with a predilection for the thoracic region. Neurological complications were usual with rapid spinal cord compression in this rare form of hydatid disease. The treatment was by surgery with a favourable outcome compared to the classic hydatid cyst of the spine.

Adolescent↗

[Tuberculosis of the posterior vertebral arch. A case report].

Tuberculosis of the spine usually involves the vertebral body and intervertebral disk. Involvement of the posterior arch is rare. We report a case of tuberculosis involving the posterior elements of the T4 and T5 vertebrae in a 38 year old woman. CT is helpful to assess bony structures whereas MRI is ideal to evaluate the neural structures. Clinical, radiographic, and therapeutic considerations regarding tuberculosis of the spine are reviewed.

Adult↗

[Tuberculous osteitis of the posterior vertebral arch: case report].

The authors report an unusual case of spinal tuberculosis involving the posterior arch of T12 without disk lesion in a 20-year-old woman presenting with posterior compression of the spinal cord. The diagnosis was suggested at CT and MR imaging and confirmed by histological study after surgical resection. CT provides good evaluation of the bony lesion and may suggest intraspinal extension. MRI is superior for evaluation of cord compression. The patient improved after surgical and medical treatment. The imaging features of this entity are reviewed.

Adult↗

[Optochiasmatic tuberculoma: complication of tuberculous meningitis. Report of a case and review of the literature].

Optochiasmatic tuberculomas are rare and have a poor prognosis if not diagnosed early and treated adequately. We report the case of 4-year-old boy who presented a chiasmatic tuberculoma after tuberculous meningitis revealed by progressive visual failure. Cerebral gadolinium enhanced magnetic resonance imaging demonstrated a chiasmatic and a brainstem ringlike enhancing lesions. Outcome was favorable with antituberculosis therapy and corticosteroids. Are recalled the diagnostic aspects, notably the neuroradiological findings, in this particular localisation of tuberculosis with a review of the similar thirty-three cases reported in the literature.

Child, Preschool↗

[CT and MRI features of spinal hydatidosis. A report of 8 cases].

PURPOSE: Hydatidosis affects the bone in 0.5 to 2% of cases, with 44% of these cases involving the spine. We report 8 cases of vertebral involvement evaluated by CT and/or MRI. Materials and Methods. This retrospective study from January 1996 to August 2000 included seven patients (5 men and 3 women) aged between 28 and 65 years old. The mean age was 45 years old. Five patients underwent CT scan (one by CT-myelography). MRI was available in 4 cases. RESULTS: Imaging showed multicystic bony lesions. Thoracic involvement was present in 4 cases, lumbar involvement in 2 cases, and sacral involvement in 2 cases. The process involved 2 adjacent vertebrae in 4 cases at the thoracic and lumbar levels and the entire sacrum in the other cases. Only one case of vertebral collapse was noted, but extension into the spinal canal was noted in all cases. Other sites of involvement were also noted, especially in adjacent soft tissues, liver and spleen. CONCLUSION: The presence of multicystic vertebral lesions with involvement of adjacent soft tissues and/or distant organs should raise the possibility of spinal hydatidosis in endemic countries.

Adult↗

[Primary Ewing's sarcoma of the cranial vault. Report of 2 cases].

Primary Ewing sarcoma of the calvarial skull is very rare, found in less than 1% of the cases. Frontal and parietal convexities are the common sites of occurrence. We report two cases of primary Ewing sarcoma of the skull (in 13- and 14-year-old boys. The first tumor involved the right temporal region and exhibited unclear osteolytic appearance on skull x-rays while computed tomography showed an extraaxial enhanced mass and bone sclerosis with spiculated periosteal reaction. In the second case, the tumor was temporoparietal. Plain films demonstrated a large osteolysis and computed tomography revealed extensive bone destruction involving both the inner and outer tables. In both cases, the C scan revealed extraaxial enhanced masses with intracranial and extracranial extension. Radial resection was performed. Adjuvant chemotherapy was given and no recurrence or metastasis has occurred two years later.

Adolescent↗

[Simple cyst of the cerebellum. Report of a case].

The authors report a case of simple cyst of the cerebellum documented by magnetic resonance imaging in 42-year-old men with clinical symptoms of expansive cerebellar lesion. No communication with the ventricle, no mural nodule and no enhancement after contrast injection were noted. The postoperative outcome was satisfactory after surgical removal. Histological examination of the cyst wall showed normal cerebellar tissue without epithelial lining neither tumoral features. A brief review of the seventeen cases founded in the literature is given.

Adult↗

[Contribution of imaging to the diagnosis of Darier-Ferrand's cranio-facial dermatofibrosarcoma. Report of 2 cases].

Dermatofibrosarcoma protubans of Darier-Ferrand is observed in about 0.1% of al malignant skin tumors. Head and face localization in uncommon, estimated to account for about 1 to 10% of all lesions. Relapse is frequent and metastasis in uncommon. Diagnosis is often made late. Surgery is the basic treatment. We report two cases of dermatofibrosarcoma of Darier-Ferrand with head and face localizations. In one case, the tumor extended inside the skull and spread to the superior longitudinal sinus. This is the only such reported case found in the literature. CT scan is more useful for studying the bony tables and the cranial content. MRI provides precision for soft tissue tumors and angio-MRI is particularly useful for analysing with accuracy vascular relations of the tumor.

Adult↗

[MR imaging in the diagnosis of intradural extramedullary tuberculoma. Report of a case and review of the literature].

Intradural extramedullary tuberculoma without any bony involvement is exceptional. Nineteen cases were found in the literature. We report the case of 5-year-old boy who presented acute paraplegia 8 months after a tuberculous meningitis under antituberculous treatment. Dorsal gadolinium enhanced MRI revealed an intradural extramedullary bunch-shaped enhancing mass at T5-T6 level. The tuberculous nature was confirmed by histology after surgical removal of the lesion followed by a good recovery. To our knowledge, this is the first intradural extramedullary tuberculoma detected by MRI. We underline the role of MRI in the diagnosis of this particular localisation of tuberculosis.

Child, Preschool↗

[Sub-occipital Pott's disease. Diagnostic imaging in 2 cases].

Pott's disease is the most common form of bone and joint tuberculosis, notably in the thoracolumbar spine. The sub-occipital localization remains exceptional, raising a major risk of spinal instability and severe bulbo-medullary complications. We report 2 new cases of tuberculous spondylodiscitis at the cervico-occipital junction revealed by signs of spinal compression associated with torticolis and dysphagia. The diagnosis was provided by CT scan and MR imaging and was confirmed histologically on a transoral biopsy of the retropharyngeal abscess. The patients were successfully treated with antituberculosis drugs combined with external stabilization of the spine. The diagnostic aspects, notably the neuroradiological findings in this particular localization of Pott's disease are recalled.

Adolescent↗

[An unusual cerebral hydatid cyst].

Hydatid cysts of the brain are very rare. Typically, the cyst is large, spherical, with sharply defined borders. Its may calcify, and there is no surrounding edema and no rim enhancement. Sometimes, one side of the cyst wall is very close to the calvarium, with thinning of the internal table. We report a case of hydatid cyst of the brain with particular scanographic signs, bilobular with thin membranes in the posterior component. There was a destruction of the opposite calvarium with exteriorisation into hypodermic soft tissue.

Brain Diseases↗

[A rare primitive neuroectodermal tumor: the medulloepithelioma].

Primitive neuroectodermal tumors (PNET) is a name used to describe rare and highly malignant tumors composed of undifferentiated cells resembling germinal or matrix cells of the embryonic neural tube. These tumors occur most commonly in the first decade of life, and have a particular radiological, histological and evolution features. We report a case of a PNET in an 8-year-old boy who presented intracranial hypertension studied with computed tomography scan, which demonstrated a sharply circumscribed expansive mass in the frontoparietal deep white matter, with a large cystic component, which was considered at first as a glial tumor. It was treated by total excision, and the histologic study demonstrated a medulloepithelioma. We studied the concept of PNET and their pathological, radiological and prognostic features.

Brain↗

[Syphilitic spinal cord gumma].

Syphilitic spinal cord gumma Syphilitic gummas of the central nervous system are exceptional and are in general described in the brain. We report the case of a Brown-Sequard syndrome in a 25-year-old patient. The cervical myelography and the brain CT as well as the vertebro-occipital junction were normal. The diagnosis of multiple sclerosis was evoked and corticosteroid therapy was initiated. The patient experienced clinical improvement. Two years later, the patient was readmitted. Immunological reactions for syphilis were positive, in serum and CSF. Tests for HIV were negative. The MRI showed a cervical spinal cord process at the C3 level with adhesive spinal associated arachnoiditis. Penicillin therapy was started prior to surgery for the spinal process. The syphilitic nature was confirmed by pathology. To our knowledge, the MR appearance of a syphilitic gumma of the spinal cord has not been described previously in the scientific literature.

Adult↗

[Contribution of spiral CT scan and MRI in spinal tuberculosis].

Spinal tuberculosis is the most frequent skeletal involvement in tuberculosis. The purpose of this study was to demonstrate the importance of the MRI and the helicoidal CT scan in the diagnosis of spinal tuberculosis. A retrospective study was conducted in 23 patients with spinal tuberculosis. The methods of investigation were helicoidal CT scan in 15 patients and MRI in the other eight patients. In the all cases with helicoidal CT scan, the features of the spinal tuberculosis were seen as an anterior vertebral body destruction with a paraspinal or epidural extension in 12 cases and a sequestrum formation in 5 cases. The analysis with helicoidal CT scan showed a gibbous deformity in 5 cases, a disk space narrowing in 14 cases and evaluated the extension very well. The MR imaging features showed one case in an early stage without features on the plain radiographs, and detected 3 cases of intramedullary lesions. A disruption of the longitudinal posterior vertebral ligament was found in one case and skip lesions at the granulomatous stage in 2 cases. MRI is superior to CT scan even helicoidal CT at the early lesion stage, skip lesions and the ligamentous or medullary lesions. For other lesions (bone, disk, extension), the MRI and CT scan are the same with an advantage for CT scan in osseous lesions.

Adult↗

[Dermoid cyst of the conus medullaris revealed by chronic urinary retention. Contribution of imaging].

We report a case of congenital dermoid cyst of the conus medullaris without associated dysraphic lesion treated surgically. An 18-year-old man had a one-year history of bladder sphincter disorders and more recent acute renal failure with urinary tract infection. The diagnosis of intramedullary tumor was provided by myelo CT and MRI confirmed by histology. At 10-month follow-up, the postoperative course was good.

Adolescent↗

[Vertebral body exocytosis and spinal cord compression].

Osteochondroma is a cartilaginous tumor, the most common benign tumor of bone. It may involve solitary or multiple exostoses (or osteochondromatosis) usually in hereditary multiple exostosis. The authors report a case of 13-year-old girl with a family history of hereditary multiples exostoses who presented with bilateral sciatica and cauda equina compression. The MRI showed a tumor of the L1 vertebral body. After surgery, pathologic specimens revealed the lesion to be an osteochondroma. Involvement of the vertebral column has been estimated from 1.3 to 4%. Spinal cord compression is rare. CT provides the analysis of the components of the tumor and clearly demonstrates it's intracanalar extension. MRI is superior in visualizing spinal cord compression. The prognosis is favorable after a surgical decompression.

Adolescent↗