An improved method for chromosome preparation from mouse liver.
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Animals↗
Biomedical subjects
N C Sun
Publications and source records attributed to N C Sun.
Nonclostridial emphysematous nephritis, ureteritis, cystitis and adrenalitis due to Escherichia coli.
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Adrenal Gland Diseases↗
Hepatitis associated with myocarditis. Unusual manifestation of infection with Coxsackie virus group B, type 3.
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Adult↗
Coagulation abnormalities in rheumatoid disease.
Forty-one patients with rheumatoid arthritis, including 6 with acute vasculitis, 13 with chronic vasculitis, and 22 without vasculitis, were studied for evidence of intravascular coagulation and fibrinolysis (ICF). The mean plasma fibrinogen levels were elevated in all groups. The fibrinogen, platelet count, and fibrin split products were usually elevated in acute vasculitis. Fewer patients on corticosteroids had abnormal coagulation tests. Active plasmin was detected in 12 patients primarily with chronic vasculitis. Plasminogen activator activity was not diminished in vascular endothelium of normal appearing skin of those patients with or without vasculitis. None of the patients demonstrated decompensated intravascular coagulation and fibrinolysis. The results suggest overcompensated ICF occurring in rheumatoid arthritis, but rheumatoid patients with vasculitis cannot be clearly distinguished from those without vasculitis on the basis of the usual tests performed for coagulation and fibrinolysis abnormalities.
Adrenal Cortex Hormones↗
Giant cell carcinoma of the liver: occurrence in a patient with ileal carcinoid, medullary breast carcinoma and pulmonary aspergillosis.
Pure giant cell carcinoma of the liver is a rare tumor that is usually associated with cirrhosis. Its occurrence in a young woman without evidence of cirrhosis, and in association with two other uncommon tumors, is described in this report.
Adult↗
Cardiac tamponade as a presentation of malignant thymoma.
Morphologic, cytochemical and immunocytochemical studies of pericardial fluid from a 30-year-old man presenting with cardiac tamponade are described. Based on the results of the immunocytochemical studies and the histologic examination of excised pericardium, a diagnosis of malignant thymoma was made. This is the first documented case in which malignant cells were found in the pericardial effusion in a patient with invasive thymoma. The significance of using a multidisciplinary approach to the study of body fluids is discussed.
Adult↗
Immunoperoxidase staining of the choroid plexus in systemic lupus erythematosus.
Immune deposits in the choroid of patients with systemic lupus erythematosus (SLE) are thought to relate to the pathogenesis of central nervous system (CNS) SLE. Using an immunoperoxidase technique, we found the presence of immunoglobulin heavy and light chains in the choroid stroma and/or in the ependymal cells in all of 7 patients with SLE, 2 of 4 with rheumatoid arthritis, but not in 3 subjects without autoimmune disease. The occurrence, pattern or intensity of the immunoglobulin deposits did not distinguish the patients with or without clinical neuropsychiatric manifestations. Thus, the presence of immune deposits in the choroid plexus is not specific for CNS involvement in SLE.
Antibodies, Antinuclear↗