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Biomedical subjects

N Bradai

Publications and source records attributed to N Bradai.

5 recordsLinked to original sources
PubMed2006

Fatigue after stroke.

OBJECTIVES: To examine the phenomenon of fatigue after stroke and to review the knowledge about frequency, consequences, associated factors, physiopathology and treatment. MATERIALS AND METHOD: Medline was systematically searched with the following keywords: stroke, fatigue, sleep disorders, exercise, and rehabilitation. All relevant articles found in the references were screened as well. RESULTS AND DISCUSSION: Fatigue is a common complaint after stroke and occurs in 39-72% of stroke survivors. Some studies show a severe functional impact of this symptom as well as a high mortality rate. Available evidence concerning associated factors is limited, but fatigue is clearly multifactorial. Some studies show that limited exercise capacity, increased gait energy cost, sleep-disordered breathing and sleep disorders can be related to physical fatigue. Other studies show a link between fatigue and depression. The existence of primary fatigue is still controversial. Treatment must follow a diagnostic approach. Treadmill training, among other treatments, improves fitness reserve and lowering of the energy cost of hemiparetic gait, which could be useful in relieving fatigue.

Depression↗
PubMed2005

[Evaluation of the disabilities of hemiplegic patients].

OBJECTIVES: To identify and describe the most useful functional disability scales for assessing post-stroke hemiplegic patients and those used largely in clinical trials. METHODS: A literature review of Medline about the functional parameters for balance, gait and mobility, upper extremity functional abilities, and activities of daily living. The metrologic properties of the scales were specified as were their clinical use. RESULTS: Thirty-three scales were evaluated and classified into five categories: balance (6 scales), gait and mobility (4), upper limb function (11), global motricity scales (5) and independence in activities of daily living (7). DISCUSSION AND CONCLUSION: Many functional scales are useful for assessing post-stroke hemiplegic patients. To assess balance, the Postural Assessment Stroke Scale and Berg Balance Scale are the most interesting. The Functional Ambulation Classification and the Timed Up and Go Test are the most relevant to assess gait and mobility. The Action Research Arm Test is largely used to assess upper limb functional abilities. The Functional Independence Measure and the Barthel Index are largely used to assess independence in activities of daily living.

Disability Evaluation↗
PubMed2002

[Efficacy at six months of the botulinum toxin A in the post-stroke lower limb's muscular overactivity].

OBJECTIVE: Post-stroke hemiplegic patients are often disabled by a muscular overactivity of the lower limb which can be treated by botulinum toxin A (BTX). The aim of this study was to assess the length of this efficiency as expressed by the patient. MATERIAL AND METHOD: The study was conducted among consecutive patients with post-stroke hemiplegia, disabled by a distal muscular overactivity of the lower limb. The injection of BTX (Botox Allergan) was given under electrostimulation guidance. Efficiency was assessed by the patient at 1, 3 and 6 months, by means of a three-point scale (absent, real but not enough, very good), on the basis of individual objectives previously defined after the precise description of the symptoms, their type of triggering and their functional impact. RESULTS: Fifty-seven sessions were conducted in 36 patients. At 1 month, 81% of the sessions were efficient, 39% with very good results. At 6 months, 57% of the sessions were still efficient with 25% of very good results. The best results were observed on the permanent extension of the great toe: the efficiency remained very good at 6 months for 47% of the sessions. CONCLUSION: Having been assessed by the patients on the basis of individual objectives, the good result of the treatment by BTX can persist for more than 6 months. This assessment is partly subjective but is, in clinical use, the main basis for the treatment discussion.

Adult↗
PubMed1991

[Thalamocapsular metastasis of muco-epidermoid adenocarcinoma of the parotid gland].

A 58 years woman with muco-epidermitis carcinoma of the left parotid gland treated by parotidectomy and external radiation developed seven years later a left hemianopsia and moria related to thalamo-capsulo-lenticular lesions. Three stereotactic biopsies were performed. Neuropathological examination confirmed a secondary lesion of carcinoma with the same histological features than primary lesion of the parotid. Due to the metastasis location treatment consisted in external radiotherapy guided by stereotactic coordinates.

Adenocarcinoma↗