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Biomedical subjects

N B Genieser

Publications and source records attributed to N B Genieser.

72 records · Page 4Linked to original sources
PubMed1975

Bone scanning-osteogenic sarcoma. Correlation with surgical pathology.

This study was designed to evaluate the role of isotopic scanning in determining the local extension of osteosarcoma. During the period of the study, 13 patients wtih biopsy proven osteosarcomas were evaluated. The results indicated that in no case did the isotope scan demonstrate greater intramedullary extension of tumor than the routine roentgenographic examination. In addition, despite good correlation between the roentgenogram, scan, and histologic evaluation of tumor extent, all of which showed no evidence of malignancy near the area of surgery,there have been to date 3 local recurrences.

Adolescent↗
PubMed1975

Campomelic dwarfism.

The campomelic syndrome is a short-limb, usually fatal, neonatal dwarfism. It is characterized by bowed lower limbs, especially the tibia, usually associated with a cutaneous dimple over the anterior skin. There is delayed calcification of the epiphyses and delayed mineralization of the spine and pelvis. The cartilages of the tracheobronchial tree are hypoplastic, contributing to death from respiratory problems. Other associated abnormalities are unusual appearing facies, cleft palate, absent olfactory nerves and talipes equinovarus. Less commonly seen are cardiac, renal and brain anomalies.

Adult↗
PubMedDate not supplied

Interrupted aortic arch: diagnosis with gadolinium-enhanced 3D MRA.

PURPOSE: Our goal was to describe the use of gadolinium-enhanced 3D MR angiography (MRA) in the diagnosis of interrupted aortic arch (IAA). METHOD: A review of our MR data base from a 1 year period yielded three patients (1 day, 8 days, and 16 years old) with IAA. All were referred for evaluation of aortic arch abnormalities, only one of whom had suspected IAA. Patients were imaged at 1.5 T with a 3D spoiled gradient echo pulse sequence (TR/TE 3.8-8/1.3-2.7 ms) following the administration of intravenous gadolinium chelates. Surgical correlation was available in all cases. RESULTS: In the patient with clinically suspected IAA, a previously unsuspected aberrant right subclavian artery was identified that was not seen on preoperative echocardiography. In another patient with a history of previous mediastinal surgery, IAA was diagnosed without concomitant cardiac anomalies, suggesting surgical ligation. In the remaining patient, IAA was detected as well as a patent truncus arteriosus. CONCLUSION: Gadolinium-enhanced 3D MRA may provide for a rapid diagnosis of IAA that may not be possible with other noninvasive modalities. The rapid acquisition time enables unstable pediatric patients to spend minimal time in the MR suite.

Adolescent↗