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N B Alexander

Publications and source records attributed to N B Alexander.

At least 37 records · Page 2Linked to original sources
PubMed1996

Postural control in young and elderly adults when stance is perturbed: dynamics.

Responses in maintaining or restoring standing balance were measured in 24 healthy young and 15 healthy elderly adults (mean ages 26 and 72) under four task conditions: two involving self-generated motions and two involving imposed disturbances. The two primary objectives of the study were to quantify the whole-body dynamics of these responses and to identify any age related differences in those dynamics. Response dynamics were analyzed using a seven-link biomechanical model. In terms of approximate population-mean values, maximum whole-body center of mass (CM) excursions ranged to 3 cm, maximum center of support-surface reaction (CR) excursions ranged to 8 cm, vertical reaction force changes ranged to 50 N, anteroposterior support surface reactions ranged to 30 N, maximum joint torques used per side ranged to 20 Nm and peak angular momenta about a transverse axis through the ankles ranged to 6 kg m2 s-1. The elderly adults, compared to the young tended to exhibit higher-frequency oscillations in excursions and larger horizontal excursions of their CM and CR, tended to develop larger support surface reactions and use larger response joint torques, and tended to arrest less of their angular momentum in their first cycle of response during the two imposed-disturbance tasks. Only some of these tendencies proved statistically significant. The results suggest that healthy elderly subjects with no apparent musculoskeletal or neurological impairments differ from healthy young adult subjects in their responses to modest perturbations of upright stance. However, the differences are generally not large and their magnitudes are perturbation-specific.

Acceleration↗
PubMed1996

Stepping over obstacles: dividing attention impairs performance of old more than young adults.

BACKGROUND: Tripping over an obstacle is a common cause of falls in the elderly. An earlier study of abilities to avoid stepping on suddenly appearing obstacles found that, although healthy old adults had a lower rate-of-success than young adults, the magnitude of that difference was not large. The present study inquired whether dividing attention during such a task would differentially affect young and old healthy adults. METHODS: Rates-of-success were observed in 16 young and 16 old healthy adults (mean ages 24 and 72 years) in avoiding stepping on a band of light that was suddenly projected across their gait path while they walked at their comfortable gait speed. This virtual obstacle was placed at predicted next-footfall locations to give 350 or 450 msec available response times before footfall. During most of the trials the subjects were asked, in addition to trying not to step on the obstacle, simultaneously to respond vocally as quickly as possible when red lights near the end of the walkway turned on. These attention-dividing reaction time tests were of two types: synchronized, when only red lights lit at intervals synchronized with the appearance of the obstacle, and unsynchronized, when green or yellow lights lit in addition to the red lights, with lighting intervals not synchronized with the appearance of the obstacle. RESULTS: When synchronized and unsynchronized reaction time tests were conducted concurrently with the obstacle avoidance tasks, mean rates-of-success in avoidance decreased significantly in both young and old adults. With available response times of 350 msec, mean success rates decreased from their no-division values in the young adults by 14.7% for synchronized reaction and by 19.9% for unsynchronized reaction, attention-dividing tests. Corresponding mean decreases for the old adults were 32.0 and 35.7%. This age difference in the effects of dividing attention was significant. CONCLUSION: Both young and old adults had a significantly increased risk of obstacle contact while negotiating obstacles when their attention was divided, but dividing attention degraded obstacle avoidance abilities of the old significantly more than it did in the young. Diminished abilities to respond to physical hazards present in the environment when attention is directed elsewhere may partially account for high rates of falls among the elderly.

Accidental Falls↗
PubMed1996

Effects of age on rapid ankle torque development.

BACKGROUND: When balance is disturbed, often only fractions of a second are available in which to make the initial responses needed for its restoration. Abilities to develop joint torques rapidly may be critical to such responses. We undertook this study to quantify age effects among healthy adults in abilities to develop ankle joint torques rapidly. METHODS: Ankle dorsiflexion (DF) and plantarflexion (PF) torque development during rapid isometric and during isokinetic (30, 60, 120, 180, and 240 deg/sec) exertions was assessed in 24 healthy young (mean age 23 years) and 24 healthy old adults (mean age 72 years). The effects of age, gender, and torque direction on the times needed to reach given torque magnitudes, maximum rates of isometric torque development (MRTD), and maximum isokinetic torques were examined. RESULTS: The old adults required substantially more time to reach given torque magnitudes than the young adults. For example, the young and old females needed approximately 236 and 337 msec to develop 15 Nm of DF torque, of which 141 and 164 msec were reaction times. Isometric MRTD were 25 to 36% lower in the old than in the young adults. The age declines in isometric torque development time were associated with losses in maximum isometric strength. Maximum isokinetic torques developed by the old were 20 to 40% lower than those of young adults. The percent losses in isokinetic torques with age were independent of joint angular velocity for PF, but increased with velocity for DF. CONCLUSIONS: We found substantial age declines in abilities of healthy old adults to rapidly develop ankle joint torques. The capacities of even healthy old adults to recover balance or to carry out other time-critical actions that require moderate-to-substantial strengths may be considerably degraded by these declines.

Adult↗
PubMed1996

Do neural factors underlie age differences in rapid ankle torque development?

OBJECTIVES: Rapid torque development is substantially slower in healthy old adults compared with young adults, but the underlying cause of this age-related loss remains unclear. Measurements of myoelectric signals in ankle dorsi- and plantarflexor muscles during rapid exertions were used to explore the extent to which the loss might be attributed to neural factors. METHODS: Myoelectric signals were measured in a laboratory setting in 24 healthy young and 24 healthy old adult volunteers during rapid isometric and isokinetic torque development. Premotor times, muscle activation rates, and myoelectric activity levels of agonistic and antagonistic muscles were quantified. RESULTS: There were few marked age differences in the premotor times or in the onset rates or magnitudes of agonistic muscles activities during maximum isometric and during isokinetic exertions. Premotor times were statistically associated with age but, in the mean, were only approximately 10 to 25 ms longer in the old. Age effects on agonist muscle activity magnitudes were significant only in the lateral gastrocnemius. Small decreases in antagonistic muscle activity levels with age were found. CONCLUSIONS: Given the outcomes of this study, the differences observed previously in rapid torque development abilities in healthy older adults, compared with healthy younger adults, seem attributable largely to differences in muscle contraction mechanisms rather than to differences in speeds of stimulus sensing or central processing of motor commands, or to differences in muscle recruitment strategies.

Adult↗
PubMed1996

Chair design affects how older adults rise from a chair.

OBJECTIVE: To determine how modifications of key chair design aspects, such as seat height, posterior seat tilt, backrest recline, seat compressibility, and armrest placement, affect how older adults rise from a chair and the seating comfort they experience. DESIGN: Cross-sectional comparison. SETTING: Congregate housing facility and university laboratory. SUBJECTS: Two groups of volunteers, Old (n = 29, mean age 84) and Young (n = 21, mean age 23). MEASUREMENTS: Analysis of time to rise, body motion (determined by use of digitized videotaping), and self-reported difficulty when subjects rose from a variety of controlled chair settings thought to represent important chair design specifications encountered by older adults. Subjects also reported their comfort while being seated in these settings. RESULTS: Lowered seat height, increased posterior seat tilt and backrest recline, and perhaps increased seat compressiblity cause increased time to rise, increased body motion, and increased self-reported ratings of rise difficulty in both Young and Old groups. Under the most challenging conditions, the effect appears to be stronger in the Old than in the Young: a few Old were unable to rise, and the Old took disproportionately longer to rise and used disproportionately greater neck motion (P generally < 0.001) compared with the Young. Arm rest placement did not alter rise performance or ratings significantly. The conditions in which rise difficulty increases or decreases do not correspond exactly to conditions in which comfort increases or decreases. Some aspects that increase rise difficulty, such as tilt/recline and seat compressiblity, may also increase comfort. CONCLUSIONS: Aspects of chair design such as lowered seat height, increased posterior seat tilt, increased back recline, and increased compressibility interfere with chair egress in older adults. While decreasing ease of egress, however, these same factors may increase seating comfort. Furniture designers and manufacturers must find a balance between degree of sitting comfort, ease of egress and the degree to which the seating device facilitates functional independence, particularly to meet the needs of disable older adults.

Adult↗
PubMed1996

Differential diagnosis of gait disorders in older adults.

The purpose of this review is to examine the causes of gait disorders in older adults, focusing specifically on the underlying diseases that are the primary causes of the disorder. A classification system for these diseases is proposed. Thus far, interventions used to reduce gait disorders yield only modest results and residual disability is common.

Age Factors↗
PubMed1996

Using technology-based techniques to assess postural control and gait in older adults.

Increasingly sophisticated instrumentation and techniques to assess gait and postural control in older adults are now available. These technology-based methods may be most useful in understanding the mechanisms underlying age-related and disease-related changes in gait and postural control. Further work is needed to ensure that these methods: (1) are used in a hypothesis-driven manner; (2) are made more simple, portable, and user friendly; and (3) are used in an appropriate and cost-effective manner.

Adult↗
PubMed1995

Association of age with the threshold for detecting ankle inversion and eversion in upright stance.

A randomized quadruple staircase method and probit analysis were used to measure the thresholds for sensation of ankle inversion and eversion by 18 healthy young and 18 healthy old subjects while standing with a foot in a servo-driven cradle. The results of over 3600 trials show that the mean threshold for detecting inversion with a probability of 75% was 0.35 degrees in the older subjects, a value significantly greater than the 0.06 degrees threshold found in the younger group. The corresponding thresholds in eversion were significantly greater in both old (0.52 degrees) and young (0.35 degrees) subjects. Significant, but smaller, age differences were also found in unipedal stance. Few significant sex differences were found. When the velocity of a 0.1 degree inversion movement was increased from 2 to 200 degrees/s the probability of detecting it rose by only 22.6%. Although significantly increased with age, the threshold for sensing rotation in the weight-bearing ankle was measured in tenths of degrees, an order of magnitude better than previously reported (non-weight-bearing) values.

Adult↗
PubMed1995

Neuropsychological predictors of complex obstacle avoidance in healthy older adults.

Global cognitive impairment in older adults has been associated with a greater risk of falling, and tripping has been implicated as an important factor in a large percentage of these falls. In order to evaluate the role of specific cognitive domains in tripping and falling, 23 healthy older adults completed basic and complex obstacle avoidance tasks, as well as a battery of neuropsychological tests. Using multiple regression analysis, a select pattern of neuropsychological measures was found to predict the decrement in performance evident as avoidance task complexity increased. Whereas measures of problem solving, response inhibition, general anxiety, and variability in attention were found to be significant predictors (in that order) of the relative decline in successful obstacle avoidance, measures of visuo-spatial discrimination and memory did not.

Accidental Falls↗
PubMed1995

Healthy young and old women differ in their trunk elevation and hip pivot motions when rising from supine to sitting.

OBJECTIVE: To describe the differences between healthy young and older women in regards to trunk elevation and hip pivot motions when rising from a supine to a seated position. DESIGN: Cross-sectional comparison. SETTING: University laboratory. PARTICIPANTS: Two groups of healthy female volunteers: young adult female controls (n = 22, mean age 23.5 years) and community-dwelling older female adults (n = 17, mean age 73.8 years). MEASUREMENTS: Subjects were videotaped as they performed three controlled bed mobility tasks, starting from a supine position: (1) rising to a seated position at the edge of a firm plinth surface (SS); and rising to a seated position without moving to the edge of the bed while either (2) using hands (SUH) or (3) not using hands (SUNH). A series of movements involving the trunk were identified as subjects performed the SS task. RESULTS: The older women were more likely to rotate and laterally flex their trunks, particularly in the later phases of the SS task. In addition, during the SS task, the older group was more likely to bear weight on their hip/gluteal area, particularly in the later phases, and more likely to use a broad pivot base, consisting of the hip and the elbow. While all young and old performed the SUH task, less than half of the older group could complete the SUNH task. Moreover, the subgroup of older adults who could not complete the SUNH task may have accounted for much of the differences between the young and the old on the SS task. CONCLUSION: Healthy young and older women differ in their ability to rise from a supine to sitting position, primarily in the strategies used to elevate the trunk and facilitate a pivot. Trunk flexion ability likely contributes to the age group differences noted in rising. These data provide the basis for a biomechanical analysis of the critical body segment motions and the strengths required to perform bed mobility tasks.

Adult↗
PubMed1995

Maintenance of balance, gait patterns, and obstacle clearance in Alzheimer's disease.

Patients with cognitive impairment, particularly as a result of Alzheimer's disease (AD), are at increased risk for falls, but it is unclear how, or if, they differ from normal adults in their balance, gait, or ability to clear an obstacle in their path. Using an optoelectronic camera system, we compared body motions and force output at the feet in patients with probable AD (n = 17) with those in healthy older adults (n = 15) while they stood on a force plate or on a beam attached to the force plate that was either stationary or accelerating. Using the same camera system and comparing this AD group with another group of healthy older adults (n = 24), we observed the AD patients during normal walking and while clearing 25- and 152-mm-high obstacles. None of the AD patients had extrapyramidal signs or musculoskeletal impairments. Compared with healthy older adults, normal walking speed was significantly slower in the AD group (p < 0.0001). While clearing either obstacle, the AD patients were significantly slower in their approach (p < 0.0001) and crossing (p < 0.0001) speeds and landed closer to the obstacle after having crossed it (p < 0.02). Moreover, the percent of trials in which a subject made contact with an obstacle was significantly higher in patients with AD (p < 0.005).(ABSTRACT TRUNCATED AT 250 WORDS)

Aged↗
PubMed1994

Effects of age and available response time on ability to step over an obstacle.

BACKGROUND: Falls during walking are often triggered when a foot contacts an obstacle in its path. Yet little is known about the ability of individuals of any age to successfully negotiate obstacles, especially under time-critical conditions. METHODS: The gait of 24 young and 24 old healthy adults (mean ages 23 and 73 years) was studied as they approached and tried to avoid stepping on a band of light, not knowing when or where it might appear on an 8 m-long walkway. This virtual obstacle was placed at the predicted location of the next footfall with available response times (ART) before heel strike that were varied randomly in 50 ms increments from 200 to 450 ms. In addition, their gait was observed as they stepped over a fixed virtual obstacle and over an obstacle that appeared with approximately a 1000 ms ART. RESULTS: The old had an increased risk of obstacle contact while negotiating obstacles under time-critical conditions (p = .082). Mean rates-of-success (RS) in obstacle avoidance for the young ranged from .205 at a 200 ms ART to .969 at a .450 ms ART. Corresponding mean RS for the old were .157 and .920. Lower extremity simple reaction time (SRT) test made under static conditions showed that the mean SRT of the old were approximately 80 ms longer than those of the young. Regression analyses suggested that the old in fact would have needed only 30 ms additional ART to achieve RS equal to that of the young for obstacles appearing with ART from 300 to 450 ms. CONCLUSIONS: Reductions in ART significantly decreased RS. Delays as small as 50 or 100 ms in observing or reacting to obstacles in real-life situations may significantly lower the rate of success that subjects of any age have in avoiding them. Age differences in SRT do not always reliably indicate age differences in obstacle avoidance under time-critical situations.

Accidental Falls↗
PubMed1994

Stepping responses of young and old adults to postural disturbances: kinematics.

OBJECTIVES: When large disturbances of upright stance occur, balance must usually be restored by taking a step. We undertook this study to examine the biomechanics of stepping responses to sudden backward pulls at the waist. Primarily, response differences between young and old healthy adults were sought. DESIGN: A controlled laboratory study. SUBJECTS: Two groups of healthy and physically-fit adult females, 12 of mean age 22 (Young) and 12 of mean age 73 years (Old). MEASUREMENTS: Response kinematics were measured. From them, the stepping strategies of the subjects were derived, including the timing, length, and height of the first step taken and the rotations of major body segments and at major body joints that occurred. RESULTS: In response to sufficiently large backward pull forces, all subjects responded by taking one or more steps backwards. No significant age group difference appeared in the smallest disturbance for which subjects sometimes used a step response. A significant age group difference appeared in the smallest disturbance at which subjects began consistently to use step responses, and that disturbance was larger for the Old than for the Young. Distinct age group differences were found in stepping strategy. At large disturbance levels, the Young mostly responded by taking a single step, whereas the Old mostly responded by taking multiple steps. The steps taken by the Old, compared with those of the Young, were significantly shorter, had significantly smaller heights, and were taken significantly earlier in the responses. Body segment and joint rotations were generally modest, and few significant age group differences were found in these kinematics. CONCLUSIONS: In restoration of perturbed balance by step-taking, the responses of the healthy, physically-fit young and old adults studied here were similar in many respects, but they differed in some important features. Joint range of motion (ROM) limitations are unlikely to explain age group differences in stepping responses to postural disturbances among healthy subjects because the ROM actually used in any of the responses observed were substantially smaller than the ROM available.

Adult↗
PubMed1993

Postural control in young and elderly adults when stance is challenged: clinical versus laboratory measurements.

The use of dynamic posturography (EquiTest) for the characterization of postural control biomechanics would be aided by specific knowledge of what the measured data imply about body segment movements. To investigate this issue, the biomechanics of a group of 15 healthy elderly subjects were compared to those of healthy young subjects by using both dynamic posturography and a laboratory movement and force measuring system. The results from EquiTest were analyzed by 1) routine clinical interpretation of data and 2) a clinical research interpretation by subjecting the EquiTest parameters to additional statistical comparison of mean performance of the young and elderly groups. The young-elderly differences from the 2 EquiTest analyses were then compared to the young-elderly differences derived from the laboratory protocol. The routine clinical interpretation of EquiTest data identified the same increases in sway shown by the laboratory study, but did not reveal the more subtle differences indicated by the laboratory study. When the EquiTest data were subjected to additional statistical analysis, the characterization of difference between young and elderly subjects was the same as that of the laboratory study, with the exception of issues of head versus trunk movement, a measure not made by EquiTest. This essential similarity in the characterization of elderly compared to young subjects by both systems suggests 1) that EquiTest is able to detect subtle differences in biomechanics of postural control between young and elderly healthy adult groups and 2) that implied movements of center of gravity, trunk versus lower limbs, and strength of reaction measures are consistently detected by both EquiTest and the laboratory kinematics and dynamics measurement systems.

Adolescent↗
PubMed1992

Biomechanical analyses of rising from a chair.

Quantification of the biomechanical factors that underlie the inability to rise from a chair can help explain why this disability occurs and can aid in the design of chairs and of therapeutic intervention programs. Experimental data collected earlier from 17 young adult and two groups of elderly subjects, 23 healthy and 11 impaired, rising from a standard chair under controlled conditions were analyzed using a planar biomechanical model. The joint torque strength requirements and the location of the floor reaction force at liftoff from the seat in the different groups and under several conditions were calculated. Analyses were also made of how body configurations and the use of hand force affect these joint torques and reaction locations. In all three groups, the required torques at liftoff were modest compared to literature data on voluntary strengths. Among the three groups rising with the use of hands, at the time of liftoff from the seat, the impaired old subjects, on an average, placed the reaction force the most anterior, the healthy old subjects placed it intermediately and the young subjects placed it the least anterior, within the foot support area. Moreover, the results suggest that, at liftoff, all subjects placed more importance on locating the floor reaction force to achieve acceptable postural stability than on diminishing the magnitudes of the needed joint muscle strengths.

Adult↗
PubMed1992

Postural control in young and elderly adults when stance is perturbed: kinematics.

Increased postural sway and falling are associated with aging and are likely related to problems with postural control in the elderly. We investigated the motions of individual body segments in 24 healthy young adults and 15 healthy elderly adults (mean ages 26 and 72) in response to four tasks: (a) standing with feet flat on an anteriorly accelerating platform (Flat Translation); standing on a narrow beam support that was (b) stationary (Beam Standing) and (c) accelerating anteriorly (Beam Translation); and (d) standing on a rotatable but otherwise stationary springboard (Springboard Standing). An optoelectronic camera system was used to measure rotations of body segments, particularly regarding their maximum excursions, time to first rotation response, direction of initial rotation, and time to first rotation reversal. In general, larger rotation excursions were noted in the elderly compared to the young group, particularly in the Beam Standing and Beam Translation tasks, but the magnitude of rotation difference was small. All rotation magnitudes were well within the available ranges of motion of the body joints. In both excursion magnitudes and directions of initial rotation, the elderly showed greater variability than the young. In the Beam Translation task, the elderly group, compared to the young, tended to rotate their upper body segments more than in the Flat Translation task. These data suggest that healthy elderly adults with no apparent musculoskeletal or neurological impairments have small but consistent differences in postural control kinematics, particularly when more challenging conditions are presented. Moreover, these data provide the basis for biomechanical analyses of joint torques and other dynamic requirements of these responses.

Adult↗