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Biomedical subjects

N Agarwal

Publications and source records attributed to N Agarwal.

At least 217 records · Page 12Linked to original sources
PubMed1979

The sterols of the khapra beetle, Trogoderma granarium Everts.

The khapra beetle, Trogoderma granarium Everts, does not dealkylate and convert dietary C28- or C29-Phytosterols to C27-sterols such as cholesterol. There is, however, an increase in the concentration of cholesterol and campesterol in its tissues relative to the dietary concentrations of these sterols, presumably as a result of selective uptake.

Cholesterol↗
PubMed1978

Radioimmunoassay of norethindrone : serum levels of norethindrone in lactating women after insertion of a single Silastic implant releasing norethindrone acetate.

A specific radioimmunoassay was developed for the estimation of norethindrone levels in the serum of lactating women. A conjugate of norethindrone-3-BSA was synthesized and antiserum raised against it in rabbits. The antiserum showed high affinity (1.5 x 10(9)M/L) and titer and was specific. The sensitivity of the assay was 125 pg/ml serum. Serum levels of norethindrone were estimated in 25 lactating women, inserted with subdermal implant releasing about 150 ug of norethindrone acetate daily. The norethindrone levels were initially high in the first two months. From there onwards the levels of norethindrone remained constant with an average value of 1.0 ng/ml up to six months. These values were comparable to those obtained in non-lactating women. Thus, lactation does not seem to alter or affect the release of norethindrone acetate from the subdermal implant or its metabolism.

Animals↗
PubMed1978

Effects of DDT (chlorophenotane) administration on glucose uptake and brush border enzymes in monkey intestine.

A considerable increase occurs in D-glucose uptake and brush border sucrase and lactase activities in the intestine of monkeys treated with a single oral dose of DDT. Brush border alkaline phosphatase activity remains unaffected in the pesticide treated animals. In vitro addiction of DDT has no effect on the sugar absorption and disaccharidase activities.

Administration, Oral↗
PubMed1977

Effect of 15(s)15-methyl-PGF2alpha-methyl ester vaginal suppositories on circulating hormone levels in early pregnancy.

Intravaginal administration of 15-methyl-PGF2alpha-methyl ester in the form of suppositories terminated pregnancy in 70 percent of the cases whose last menstrual periods ranged from 35 to 56 days. The use of these suppositories in 49 patients, between 57 to 80 days of gestation, dilated the cervix by 10 mm or more, in one hundred percent of the cases. A decrease in circulating levels of estradiol-17beta and progesterone was observed following 15-methyl-PGF2alpha administration. The mean estradiol-17beta levels declined by about 55.9 percent at 9 hours whereas, the corresponding fall in progesterone was 32.7 percent. This was indicative of a direct action of 15-methyl-PGF2alpha on the corpus luteum. The vaginal use of 15-methyl-PGF2-alpha-methyl ester suppositories thus appears to be a promising method for the termination of early pregnancy and for pre-operative cervical dilatation. The termination of early pregnancy appears to be partly due to the luteolytic effect of 15-methyl-PGF2alpha besides stimulating uterine contractions.

Abortion, Induced↗
PubMed1977

Amalgam containing nickel or tungsten dispersions. I.

Wetting tests were conducted to determine compatability between select dispersion powders and Ag3Sn. Subsequently, a method was perfected for incorporating nickel or tungsten powder into the Ag3 Sn ingot. Initial studies reveal good distributions of the dispersed phase in the ingots and the comminuted alloys, after amalgamation, appear to retain their normal working characteristics.

Chemical Phenomena↗
PubMed1977

Amalgam containing nickel or tungsten dispersions. II.

The technique of injecting dispersed phase particles into an Ag-Sn melt followed by rapid quenching was utilized. Results of this investigation show that a marked improvement of the brittle amalgam alloy occurs.

Chemical Phenomena↗