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Biomedical subjects

N A Slesarenko

Publications and source records attributed to N A Slesarenko.

10 recordsLinked to original sources
PubMed1991

Morpho-tribo-mechanical characteristics of the articular cartilage in animals under conditions of hypokinesis.

The influence of activity upon the structure and properties of articular cartilage has been examined in two populations of fur-bearing animals. Morphological changes in cartilage of the caged animals were noted. Friction was mentioned in a vibrotribometer and it was noted that the caged animals exhibited a lower friction coefficient than the free-moving animals. In both cases the friction initially increased with age, reaching a maximum after about three years. It is concluded that prolonged hypokinesis associated with a cage-breeding regime acts like a mechanical stress factor which stimulates the development of degenerative changes in cartilage.

Aging↗
PubMed1986

[Changes in the femur of fur-bearing animals during hypodynamia].

Under conditions of hypodynamia the form and internal architectonics of the femoral bone undergo certain changes. In young animals these changes are of quantitative character without any signs of a manifested destruction. Later on, certain indications of focal resorption appear in the spongy substance, as does partial destruction of the beams. Gradually, definite signs of osteoporosis and osteosclerosis as a result of dystrophic alterations in the osseous tissue develop. These phenomena, though progress with age, nevertheless, develop against the background of noticeable compensatory shifts in the osseous structures: increment in the mass of some osseous beams, appearance of new strengthening osseous plates in the spongiosa. The symptom complex at adaptational rearrangement of the bone under hypodynamia should be taken into account at differential diagnosis of these conditions both in the clinic and at experimental modelling.

Adaptation, Physiological↗
PubMed1986

[Structural adaptations of the articular cartilage in fur-bearing animals under conditions of mobility].

Adaptive properties of the articular cartilage and plasticity of its structures under various conditions of static-dynamic loading on joints have been studied when the data obtained in sables and minks, living in natural biocenosis and in cages, are compared. By means of optic, raster electron microscopy and microroentgenological analysis, peculiarities of structural formation of the articular cartilage have been revealed in ontogenesis, as well as succession in formation of its zonal architectonics. Conditions of prolonged hypodynamia are manifected as a number of anomalies in distribution of the cartilagenous integument of the joints affecting cellular and tissue levels of adaptation.

Adaptation, Physiological↗