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Mikio Kamimura

Publications and source records attributed to Mikio Kamimura.

29 records · Page 2Linked to original sources

Clinical outcome and survival after palliative surgery for spinal metastases: palliative surgery in spinal metastases.

BACKGROUND: The authors sought to identify treatment-related factors that influenced survival after surgical treatment for metastatic spinal tumors and to evaluate the relationship between survival and postoperative ambulation time as a factor related to quality of life. METHODS: The medical records of 81 patients with metastatic spinal tumors who underwent palliative surgery at the study institution were assessed. Univariate analysis for factors influencing survival used the Kaplan-Meier log rank statistic and multivariate analysis used the Cox proportional hazards model. The Spearman correlation test was used to analyze the relationship between postoperative ambulation and survival time. RESULTS: The patients had a median age of 59.9 years and a median survival of 10.6 months after surgery. For patients, postoperative ambulatory median survival was 16.5 months and median ambulation time was 13.8 months. By univariate analysis, anatomic site of the primary tumor, postoperative ambulation, and combined adjuvant therapy (chemotherapy plus radiotherapy) were associated with prolonged survival (P < 0.05). Multivariate analysis identified primary site and postoperative ambulatory function as independent predictors of prolonged survival (P < 0.0001). Significant correlations were found between ambulation time and survival time of patients who were able to walk after surgery (P < 0.0001), even in patients with liver (P < 0.05) or lung carcinoma (P < 0.05). CONCLUSIONS: The anatomic site of primary carcinoma and postoperative ambulation were associated with longer survival after palliative surgery for metastatic spinal tumor. When ambulation is attained after surgery, it can be preserved until late in remaining life even when the primary tumor is unfavorable. Palliative surgery for spinal metastasis can improve the quality and quantity of life.

Early Ambulation↗

Abducens nerve palsy as a rare complication of spinal surgery: a case report.

We describe a case of diplopia due to abducens nerve palsy after upper cervical spinal surgery. A 22-year-old woman presented with a chief complaint of numbness and weakness in her left hand. A spinal cord tumor was detected at the C1/2 level. These complaints disappeared after resection of the spinal cord tumor; however, she presented with diplopia due to abducens nerve palsy 3 days after surgery. Brain computed tomography and magnetic resonance imaging revealed no abnormalities. Within 1 month there was complete spontaneous resolution of the abducens nerve dysfunction. It is important for spinal surgeons to be aware of cranial nerve palsy as a potential complication of cervical spinal surgery.

Abducens Nerve Diseases↗

Multilevel subtotal corpectomy and interbody fusion using a fibular bone graft for cervical myelopathy due to ossification of the posterior longitudinal ligament.

A retrospective study of the outcomes of multilevel anterior decompression and interbody fusion for cervical myelopathy due to ossification of the posterior longitudinal ligament (OPLL) was performed to both investigate the long-term results and assess the cause of late deterioration. Twenty-seven patients (mean age, 58.1 years) underwent this procedure and were followed for at least 5 years. The severity of the clinical symptoms was described using the scoring system for cervical myelopathy proposed by the Japanese Orthopaedic Association (JOA score). The average preoperative JOA score was 7.7, and the score at final follow-up was 13.4 with a recovery rate of 62.0%. A delayed deterioration was attributed to a thoracolumbar lesion other than a compromising alteration of the cervical spine. Consequently, this method of treatment for OPLL could stop the progress of ossification and keep a physiological cervical alignment and thus provide good long-term results.

Adult↗

The accuracy and safety of image-guidance system using intraoperative fluoroscopic images: an in vitro feasibility study.

The "virtual fluoroscopy" is a new navigation system that combines image-guided surgery and C-arm fluoroscopy. The purpose of this study was to evaluate the accuracy of this system in the case of pedicle screwing. The angular deviation in the axial and sagittal planes was measured using the bodies of 50 vertebral models. Another type of model was used to evaluate the positional deviation (two dimension and three dimension). The mean angular deviation on the axial plane was 1.3 degrees and that on the sagittal plane was 1.0 degree. The positional deviation was not recognised. This system provides quite accurate information. Using this system, the surgeon can insert surgical instruments, such as pedicle screws, while confirming the real time virtual image on the monitor displaying the surgical field, including the position and direction of the instruments, without being disturbed by his own hands or instruments and without radiation exposure.

Fluoroscopy↗

Microendoscopic discectomy (MED) for lumbar disc prolapse.

Microendoscopic discectomy (MED), which combines traditional lumbar microsurgical techniques with endoscopy, is being used as a minimally invasive procedure for lumbar disc herniation. We reviewed 30 patients who underwent MED at our institution and compared their outcome with that of patients subjected to the conventional method. Laboratory data suggested that MED was less invasive surgery. Moreover, MED allowed an early return to work. However, the difficulties of this endoscopic procedure were evident, because of the limited exposure and two-dimensional video display. The potential injury of the nerve root and prolonged surgical time remain as matters of serious concern. To overcome this problem, we used an operative magnifying glass during surgery and this helped us to accomplish the procedure comfortably. We recommend the use of an operative magnifying glass in the early stage of the introduction of MED, for it is quite useful to identify the three-dimensional relationships of the structures.

Adolescent↗

Idiopathic spinal cord herniation associated with a large erosive bone defect: a case report and review of the literature.

We report a case of idiopathic spinal cord herniation associated with a large bone defect. MRI and computed tomographic myelography revealed ventral deviation of the spinal cord and erosion of the vertebral body at T6-T7. Microscopic surgery revealed a dural defect. The etiology of this condition has not been clarified. In most previously reported cases, the peak portion of the herniation was around the intervertebral disc space. In addition, in our patient, it was hard to think that the intervertebral disc has become depressed due to the pressure exerted by the spinal cord. We considered that a certain condition of the intervertebral disc, such as herniation, was one of the causes of the dural defect, and cerebrospinal fluid pulsation pushed the spinal cord toward that portion, causing herniation.

Aged↗

Preoperative CT examination for accurate and safe anterior spinal instrumentation surgery with endoscopic approach.

The purpose of this article is to introduce a new procedure for the surgical planning of thoracic anterior spinal instrumentation via endoscopy. For accurate and safe anterior screw insertion via the endoscopic approach, we devised a surgical plan based on the preoperative chest computed tomography (CT) findings obtained with radiographic markers. Using this method, we performed endoscopic thoracic spinal instrumentation surgery in 14 patients. Nine patients underwent anterior endoscopic correction and fusion of idiopathic scoliosis by Cotrel-Dubousset instrumentation, and five patients underwent anterior endoscopic spinal fixation with instrumentation. The accuracy of screw insertion was evaluated postoperatively by CT scanning. One interbody fusion cage and 53 screws were inserted in the 14 patients using endoscopy. Postoperative CT scans revealed that the screws were all accurately inserted without any neurologic complications. In conclusion, using this novel procedure for surgical planning based on CT findings obtained with radiographic markers, anterior screws can be inserted safely and accurately via an endoscopic approach.

Adolescent↗

Pro-inflammatory and anti-inflammatory cytokine increases after spinal instrumentation surgery.

We investigated the effects of instrumentation on postoperative inflammatory reaction and identified standard changes in serum cytokine concentrations after spinal surgery. Pro-inflammatory cytokines [interleukin (IL)-6 and IL-8] and anti-inflammatory cytokines [IL-10, IL-1 receptor antagonist (ra), and soluble tumor necrosis factor receptors (sTNF-R) I and II] were assayed in serum from seven patients with lumbar spinal posterior decompression, six with spinal decompression and posterolateral fusion without instrumentation and seven with spinal decompression and posterolateral fusion with instrumentation. All cytokines after spinal instrumentation increased significantly more than in other groups on postoperative days 0 and 1. Seven days after SI, IL-6, -8, and -10 had normalized, but IL-1ra and sTNF-RI and sTNF-RII remained elevated. Both pro-inflammatory and anti-inflammatory cytokines were enhanced by implants in the acute phase, whereas only anti-inflammatory cytokines were enhanced by instruments in the subacute phase.

Aged↗

Ulnar nerve palsy at the elbow after surgical treatment for fractures of the olecranon.

Despite close proximity of the fracture site to the nerve, ulnar nerve palsy after surgery for fracture of the olecranon is uncommon. We examined 18 cases of fracture of the olecranon treated surgically retrospectively to see if there were any characteristics common to 4 cases of ulnar nerve palsy. Three cases of palsy with a comminuted fracture had fair or poor reduction as revealed by both the lateral and anteroposterior radiographs taken at the time of surgery. The other case, with little displacement of the fragment, had osteoarthritic changes at the medial side of the elbow. The mechanism of development of ulnar nerve palsy is considered to be multifactorial. However, it should be noted that evaluation of reduction of the fracture, not only on a lateral radiograph but also on an anteroposterior radiograph at the time of surgery, is important to prevent the ulnar nerve from being jeopardized.

Adult↗