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Biomedical subjects

Michael S C Thomas

Publications and source records attributed to Michael S C Thomas.

6 recordsLinked to original sources
PubMed2007

Neuroconstructivism.

Neuroconstructivism is a theoretical framework focusing on the construction of representations in the developing brain. Cognitive development is explained as emerging from the experience-dependent development of neural structures supporting mental representations. Neural development occurs in the context of multiple interacting constraints acting on different levels, from the individual cell to the external environment of the developing child. Cognitive development can thus be understood as a trajectory originating from the constraints on the underlying neural structures. This perspective offers an integrated view of normal and abnormal development as well as of development and adult processing, and it stands apart from traditional cognitive approaches in taking seriously the constraints on cognition inherent to the substrate that delivers it.

Adult↗
PubMed2005

Characterising compensation. (Commentary on Ullman and Pierpont, "Specific language impairment is not specific to language: the procedural deficit hypothesis").

This article considers Ullman and Pierpont's Procedural Deficit theory of Specific Language Impairment (SLI). The theory represents an innovative attempt to fill the gap between brain and cognition in SLI, and has the potential to explain the non-linguistic as well as linguistic deficits seen in this disorder. The theory is reviewed with regard to: (1) the claims it makes on the domain-specificity of language structures; (2) the falsifiability conditions of the theory; (3) the level of detail at which compensatory processes are specified; and (4) from a computational perspective, whether the inferences that the theory draws from uneven behavioural impairments to underlying structural deficits are necessary ones.

Child↗
PubMed2003

What makes counting count? Verbal and visuo-spatial contributions to typical and atypical number development.

Williams Syndrome (WS) is marked by a relative strength in verbal cognition coupled with a serious impairment in non-verbal cognition. A strong deficit in numerical cognition has been anecdotally reported in this disorder; however, its nature has not been systematically investigated. Here, we tested 14 children with WS (mean age=7 years 2 months), 14 typically developing controls individually matched on visuo-spatial ability (mean age=3 years 5 months) as well as a larger group of typically developing controls (mean age=3 years 4 months) on two tasks to assess their understanding that counting determines the exact quantity of sets (cardinality principle). The understanding of the cardinality principle in children with WS is extremely delayed and only at the level predicted by their visuo-spatial MA. In this clinical group, only language accounted for a significant amount of the variance in cardinality understanding, whereas in the normal comparison group only visuo-spatial competence predicted the variance. The present findings suggest that visuo-spatial ability plays a greater role than language ability in the actual development of cardinality understanding in typically developing children, whereas the opposite obtains for the clinical group.

Child↗
PubMed2003

Modeling language acquisition in atypical phenotypes.

An increasing number of connectionist models have been proposed to explain behavioral deficits in developmental disorders. These simulations motivate serious consideration of the theoretical implications of the claim that a developmental disorder fits within the parameter space of a particular computational model of normal development. The authors examine these issues in depth with respect to a series of new simulations investigating past-tense formation in Williams syndrome. This syndrome and the past-tense domain are highly relevant because both have been used to make strong theoretical claims about the processes underlying normal language acquisition. The authors conclude that computational models have great potential to advance psychologists' understanding of developmental deficits because they focus on the developmental process itself as a pivotal causal factor in producing atypical phenotypic outcomes.

Humans↗