Biomedical subjects
Michael Eisenstein
Publications and source records attributed to Michael Eisenstein.
Cell sorting: divide and conquer.
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Tiny droplets make a big splash.
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Pinning the tail on the substrate.
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Search party.
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A 'pore' man's sequencing solution?
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Putting long-range mapping in reach.
A technique for performing PCR on extremely large DNA molecules offers researchers the ability to generate accurate multi-marker haplotypes for large numbers of patients--even with loci arrayed across entire human chromosomes.
Coke and chips--a winning combination?
An aptamer-based electronic sensor for the detection of cocaine demonstrates the capabilities of a sensitive and generalizable new platform for small-molecule recognition.
A new twist for DNA.
A computer-aided design strategy allows scientists to 'staple' DNA molecules into a wide variety of two-dimensional shapes, generating precisely arranged scaffolds that could serve as promising platforms for nanoscale research applications.
My enemy's enemy is my friend.
Bacteriophages form the foundation for a rapid and sensitive bacterial detection assay, capable of revealing the presence of a few dozen cells in a milliliter sample.
Tracking the wily transcription factor.
A 'paired-end ditag' (PET) strategy for pinpointing protein binding sites can reveal a wealth of information about transcription factors and other DNA-binding proteins.
Exploring how the organelles are organized.
New work from several laboratories describes ongoing efforts to explore a new proteomic frontier--mapping and indexing the protein content of the cellular organelles.
More than just 'doing the math'.
Two new articles show how computational tools continue to move beyond mere sequence-based bioinformatic analysis into more advanced arenas of prediction, deduction and network building.
Getting a DNA to do an RNA's job.
The successful in vitro evolution of a DNA enzyme based on a ribozyme could offer insights into early evolutionary events and provide guidelines for designing hardier catalytic oligonucleotides.
Sorting out the best targets.
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Circuit maps for the cell.
An assessment of the interactions between different receptor-mediated cellular signaling pathways may have revealed an unexpected degree of underlying compartmentalization and even simplicity in the cross-talk between these networks.
Stem cell therapy grows on Parkinson's-afflicted monkeys.
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