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Biomedical subjects

Mary E Duffy

Publications and source records attributed to Mary E Duffy.

5 recordsLinked to original sources

Postprocedure chest pain after coronary stenting: implications on clinical restenosis.

OBJECTIVES: The goal of this study was to analyze the incidence and predictors of postprocedure chest pain (PPCP) after percutaneous coronary intervention (PCI) and its correlation with clinical restenosis. BACKGROUND: Chest pain after PCI occurs frequently even in the absence of procedural events and is considered to be due to vasospasm or coronary artery stretch. The short- and long-term significance of PPCP after otherwise successful stenting is not clear. METHODS: We analyzed 1,362 patients undergoing coronary stenting for PPCP, procedural and in-hospital events, 30-day major adverse cardiac events, and target vessel revascularization (TVR) at 6 to 9 months. RESULTS: There were 488 patients with PPCP and, of these, 312 patients were excluded due to procedural events. The remaining 176 patients with PPCP were compared with 874 patients without PPCP. Creatine kinase-MB isoenzyme elevation occurred in 25.6% of the PPCP group versus 9.6% of the no PPCP group (p < 0.001). Despite similar reference vessel diameter, the PPCP group had larger postprocedure minimum lumen diameter, higher stent-to-vessel ratio, and higher inflation pressure versus the no PPCP group (p < 0.01). At 30 days, the emergency room visits and repeat catheterization (16% vs. 2.7%; p < 0.001) were higher in the PPCP group versus the no PPCP group, but repeat intervention was similar. At 6- to 9-month follow-up, the TVR was significantly higher in the PPCP group compared with the no PPCP group (29.5% vs. 16.6%; p < 0.01). CONCLUSIONS: Our analysis suggests micromyonecrosis and vessel stretch as causes of PPCP. Postprocedure chest pain is associated with similar short-term outcome as no PPCP, but has higher restenosis, perhaps mediated by deep vessel wall injury. Therefore, PPCP may identify patients at high risk for restenosis.

Aged↗

Methodological issues in Web-based research.

PURPOSE: To examine methodological issues associated with using the Internet and World Wide Web for scientific research, namely, issues related to the nature of the sample, the testing environment and environmental factors, privacy, and confidentiality, and response rates. METHODS: Reviews of literature and personal observation and experience. FINDINGS: Web-based research provides many advantages such as access to specific, sometimes difficult-to-find populations, speed of data access, and decreased costs for data collection and data entry. Such benefits are likely to increase as more nurse scientists use the Web for research purposes. CONCLUSIONS: Nurse researchers who use this technology must consider the methodological problems associated with Web-based methods. The research potential exists, but the methodological issues discussed in this paper are real and, if not addressed, they can seriously affect the validity of study findings.

Internet↗

The effect of an educational intervention on promoting breast self-examination in older African American and Caucasian women.

PURPOSE/OBJECTIVES: To test the efficacy of innovative, age- and race-sensitive, self-monitored, video breast health kits in increasing knowledge about breast cancer risk and screening and breast self-examination (BSE) proficiency. DESIGN: Quasi-experimental pretest and post-test design. SETTING: Dual-site study in community-based settings in the Northeast and Southeast United States. SAMPLE: 328 women (206 in the intervention group, 122 in the control group) aged 60 or older; predominantly African American (77%); mean education of 10.8 years; annual income below $10,000 (50%). METHODS: Individual pretest and post-test interviews conducted by nurses at two-week intervals assessed knowledge about breast cancer risk and screening and BSE proficiency as demonstrated on vested breast models. Intervention subjects used video breast health kits in ethnic editions designed for the study. Control subjects received educational pamphlets. MAIN RESEARCH VARIABLES: Dependent variables were knowledge about breast health and BSE proficiency measured by demonstration of inspection and palpation skills and detection of lumps in a simulation model. FINDINGS: Three multiple analyses of covariance revealed statistically significant differences in outcome variables between the intervention and control groups. CONCLUSIONS: The intervention was effective in increasing knowledge about breast cancer risk and screening and BSE proficiency in this sample of older women. IMPLICATIONS FOR NURSING: These and other educational interventions designed specifically for age and race sensitivity may enhance cancer screening with vulnerable populations. Future studies with more diverse multicultural groups are needed to improve understanding of how to best influence breast health behaviors of older women.

Black or African American↗

Women's reflections on divorce-- 10 years later.

Ten years after divorce 95 women who participated in an earlier study of divorce were asked to reflect on their lives since their divorce. They were mailed a questionnaire to describe demographic data, self-esteem, control, life assessment, and their lives since divorce. Fewer than half remarried and of those who did, 10 divorced a second time. Slightly more women partnered than married. Their overall assessment of their lives was reported positively. However, 25% felt the same or worse than they had 10 years earlier. Income was the only demographic variable correlated with self-esteem, control, and life assessment. Women used a variety of self-care actions to improve their lives and only six women went to professional therapy. Their lives and some of the actions taken are described.

Adult↗