Biomedical subjects

Mark L Williams

Publications and source records attributed to Mark L Williams.

24 records · Page 2Linked to original sources

PubMed2003

Condom use behaviors in HIV-infected African American crack cocaine users.

The purpose of this study was to investigate sexual risk behaviors and factors associated with consistent condom use of HIV+ African Americans receiving HAART who smoke crack. Participants were African Americans in Houston, Texas and over 18, being treated for HIV, and reported currently using crack. Measures included demographic variables, sexual behaviors, drug use, and nine psychosocial scales and seven escape scales. One hundred thirty seven participated in the study. Condom use was low across all partner types. Regression analyses revealed two demographic variables, and two psychosocial and one escape scale were significantly associated with intention to use condoms. One of the more alarming findings of this study concerns the large number of individuals who know they are HIV positive yet continue to have unprotected sex. The inconsistent condom use by these HIV+ individuals threatens the progress that has been made to stem the epidemic.

Adult↗

PubMed2003

Concordance between sexual behavior and sexual identity in street outreach samples of four racial/ethnic groups.

BACKGROUND: There is a discrepancy between self-reported sexual identity and sexual behavior. The magnitude of this discrepancy is unclear, as is its variation across race/ethnicity and gender. GOAL: The goal of the study was to assess the range of discrepancy in self-reported sexual identity and sexual behavior in men and women of four racial/ethnic groups. STUDY DESIGN: Self-reported data on sexual identity (homosexual, bisexual, heterosexual) and sexual behavior in the past 3 months were collected from 1494 African American, Hispanic, Asian, and white men and women in public congregation places in Houston, Texas. RESULTS: Data indicated that concordance rates between self-reported sexual identity and sexual behavior varied widely across racial/ethnic groups, with the highest rates of concordance in Asian males and females and the lowest in African American females and white males. The largest discordant category was in those self-described heterosexuals who reported partners of both genders. Breakdown of data to exclude those who reported sex trade work or illegal sources of income improved the concordance rates for African American and Hispanic subsamples. CONCLUSION: Data indicate the importance of designing and targeting HIV risk interventions and clinical screening, based on behavior and not reported sexual identity.

Adolescent↗

PubMed2003

Drug injection and sexual mixing patterns of drug-using male sex workers.

BACKGROUND: Drug-using male sex workers (DUMSWs) are known to have large numbers of drug injection and sex partners. GOALS: The purpose of this study was to describe the assortative and disassortative drug injection and sexual mixing patterns of DUMSWs. Implications of the high rates of disassortative mixing patterns of DUMSWs for HIV infection are discussed. Implications of disassortative mixing of DUMSWS with regard to DUMSWs bridging disparate HIV risk groups are evaluated. STUDY DESIGN: Data were collected from 89 DUMSWS. Data on up to six drug injection and six sex partners were collected from respondents. One hundred drug injection and 169 sex respondent/partner pairs were analyzed for the proportions of pairs that were concordant (like) or discordant (unlike) in gender, trading sex for money, race/ethnicity, and age cohort. For race/ethnicity and age, within-group differences were assessed with chi-square statistics. RESULTS: Data showed high proportions of discordant respondent/partner pairs for both drug injection and sex by gender, trading sex for money, race/ethnicity, and age. Significant within-group differences in rates of discordant pairs were found for both behaviors in relation to race/ethnicity and age. Minority persons and respondents 19 years of age or younger were more likely to be in discordant pairs. CONCLUSIONS: Direct assessment of HIV risk posed by the mixing patterns was not possible. Elaborating the mechanisms by which DUMSWs might act as an epidemiologic bridge is complex and involves more variables than were explored in this study. Nevertheless, such a study would be worthwhile.

Adolescent↗

PubMed2003

Formative evaluation of an intervention to increase compliance to HIV therapies: the ALP project.

Non-adherence to highly effective antiretroviral medications can lead to treatment failure and the development of drug-resistant strains of HIV, and may result in an epidemic of treatment resistant HIV. This article describes a theory-based intervention (ALP) that was developed to increase adherence to HIV therapies among low-literacy populations of HIV positive African American women. The ALP intervention consists of a cartoon book and a cassette tape suitable for individuals with less than a 3rd-grade reading level. Qualitative data were collected through focus groups and expert panel interviews to conduct a formative evaluation. The results indicated that constructs of the Health Belief Model and Social Cognitive Theory were recognizable by behavioral scientists and that the materials would be used as intended by the target population to achieve the desired behavior change. This type of evaluation is a cost-effective method that can be used to develop effective interventions and obtain community buy-in.

Black or African American↗

PubMed2002

Effective targeted and community HIV/STD prevention programs.

Community interventions and interventions targeting specific groups at risk of STDs/HIV have demonstrated significant impacts on sexual behavior, particularly condom use and safer sex. The scientific evidence suggests the factors that make these interventions particularly effective include the establishment of community, including business and CBO partnerships; maintainance of the intervention post-research funding; and buy-in by the community or target group. The modification of risky normative beliefs through the use of opinion leaders and role models, and through intervention delivery by peer educators, is an important facet of such interventions. Interventions delivered by health professionals, absent a community base, appear to be unsuccessful. Where cultures or subcultures are targeted, the close involvement of such groups in the design and delivery of messages is critical to their success. Diffusion of interventions through existing social networks further extends the intervention into the community and acts to reinforce and maintain changes in peer norms toward safer sexual behavior. The available data confirm that community or medical infrastructure-based interventions are effective in changing sexual behavior and can reach a wider range of the population than face-to-face programs if they incorporate peer educators as role models in modifying norms, and if diffusion of the intervention is integral to the design.

Community-Institutional Relations↗

PubMed2002

Sexual risk behaviours and STIs in drug abuse treatment populations whose drug of choice is crack cocaine.

We investigated sexually transmissable infection (STI) prevalence in 407 drug users in three drug treatment programmes in two Texan cities and associated demographic and sexual behaviours. Data analysis focused on differences between those for whom crack cocaine was the drug of preference compared with other drugs, since crack is associated with sexual arousal and a sex for drugs economy. Data indicate that having crack as a drug of preference is significantly associated with increased levels of previous STIs, previous drug treatment, African-American race, selling or buying sex for drugs or money, and increased infection markers for syphilis, chlamydia and herpes simplex-2. Crack preference was also significantly associated with lower rates of injecting drugs or sharing injection equipment and hepatitis C infection markers. Crack preference in heterosexual respondents was significantly associated with increased partner numbers in the past four weeks, more female partners for men and more vaginal sex contacts for men. Analysis of sex differences comparing those for whom crack was the preferred versus nonpreferred drug indicated that female crack users were significantly more likely to engage in oral sex. This supports previous ethnographic data suggesting that oral sex is a common mode of sex for drugs exchange in crack houses. In 7.4% of the total sample (14.4% of the crack-preferring sample), treatable STIs were detected. These data suggest that drug users generally, and crack-using populations in particular, in drug treatment programmes should be routinely screened for STIs as an integral part of drug treatment.

Adolescent↗