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Biomedical subjects

Marek Rekas

Publications and source records attributed to Marek Rekas.

17 recordsLinked to original sources
PubMed2006

Multifocal diffractive intraocular lenses in cataract surgery--preliminary report.

PURPOSE: Evaluation of the efficacy of multifocal, diffractive intraocular lenses in cataract surgery. MATERIAL AND METHODS: 20 eyes in 10 patients, mean age 64 +/- 9 years, included in the study, undergoing phacoemulsification of the cataract with implantation of diffractive MIOL (AcrySof ReSTOR, SA60D3, Alcon). Follow-up was performed for a period of 6 months. Postoperative evaluation performed five times included: visual acuity for distance and near without and with best correction, contrast sensitivity, patient satisfaction in 10-grade scale, degree of independence from glasses and frequency of lighting effects. RESULTS: After 6 months from surgery uncorrected distance visual acuity > or =1.0 was achieved in 55% of operated eyes (6/11), and the best corrected in 91% (10/11). Uncorrected near visual acuity in 2-6 months after surgery was achieved in all patients. Contrast sensitivity for spatial frequencies in the range 12 and 18cdg was decreased, but in 6 cdg was normalized after 6 months of observation, and in 3 cdg was normal. Subjective patient satisfaction in 10-grade scale was on average in the first day after surgery 7.9 points and after 6 months 9.3. The necessity to use glasses (30%) and lighting effects had no bearing on subjective patient satisfaction perception. CONCLUSIONS: Multifocal diffractive lens implants are able to restore good visual acuity independent of distance and is effective and safe method in cataract surgery.

Aged↗
PubMed2006

Comparison of contrast sensitivity after implantation of diffractive lens SA60D3 and monofocal lens MA60BM.

PURPOSE: Comparison of CSF in groups with diffractive lens SA60D3 and with monofocal lens MA60BM, and applying results to healthy population. MATERIAL AND METHODS: The study included 3 groups of patients. First group consisted of 10 patients, who have undergone implant surgeries with diffractive lenses SA60D3 in both eyes; second group included 9 patients after implant surgeries with monofocal lenses MA60BM in both eyes. Third group included 10 patients with clear own lens. Groups were homogenous to number of patients, age and gender structure, as well as BCVA. CSF was determined for each eye. In the case of operated patients studies were performed 6 months after surgery. Homogeneity of groups was determined with Kruskal-Wallis test, but results of the studies were tested with variance. Results were shown in normalized CSF version. RESULTS: In conducted studies there was no statistical difference in specific evaluated cpd (3, 6, 12, 18) between SA60D3 group and MA60BM group after 6 months from surgery (p = 0.892, p = 0.926, p = 0.564, p = 0.9953). The above results were obtained by testing variance at confidence level p < or = 0.01. At the higher confidence level p < or = 0.05 there was significant difference between SA60D3 group, MA60BM group and healthy control. CONCLUSIONS: Diffractive lenses SA60D3 decrease CSF in comparable range as monofocal MA60BM lenses, which does not change acceptable standard for quality vision for monofocal lenses, that is currently accepted.

Aged↗
PubMed2006

[Multifocal intraocular lenses].

Multifocal intraocular lenses are the new option not only in cataract surgery, but either in refractive surgery. Use of multifocal lenses make patients less dependent on spectacle, than after implantation of monofocal intraocular lenses. In this article we present an actual review of multifocal intraocular lenses. Two main types of the implants: refractive and diffractive are described with their detailed characteristics. Special attention we paid on advantages and disadvantages as well as some limits to implantation of the multifocal implants.

Accommodation, Ocular↗
PubMed2005

[Effect of local abnormalities and systemic disorders on phacotrabeculectomy and the post-operative period].

UNLABELLED: The aim is to present that local abnormalities of eyes chronically treated for glaucoma and cardiovascular, metabolic disorders may influence the course of phacotrabeculectomy and post-operative period. MATERIAL AND METHODS: The research covered 68 patients. In 89 eyes phacoemulsification of cataract connected with Cairns-type trabeculectomy and implantation of lens prosthesis has been performed. The patients were divided into two groups: I group - 37 patients, 45 surgeries. All patients were chronically treated for arterial hypertension and other cardiovascular disorders. 7 patients had non-insulin-dependent type II diabetes mellitus without diabetic retinopathy. II group - 31 patients without cardiovascular and metabolic disorders, 44 surgeries. Stromal atrophy and posterior synechiae were recognized as local abnormalities (12 eyes in I group and 18 eyes in II group). They were released during phacotrabeculectomy. RESULTS: In post-operative period, higher coefficients of complications such as hematoceles or blood in the anterior chamber were shown in both groups, more incidents of fibrinous reaction in I group and exudate in the anterior chamber after release of posterior synechiae in II group. Statistically significant difference at p=0,016 was observed only in comparison of the incidence of complications after release of choroid-lens synechiae in I group, in comparison to II group, where synechiae were not released. Choroidal detachment was observed in 8 eyes of I group and in 1 eye of II group. Anterior chamber reconstructed in 3 eyes of I group and 1 of II group was noted. In one case of booth groups, drainage of the suprachoroid space were performed. The study didn't show statistically significant differences in the frequency of fibrinous reaction or inflammatory exudates in 9 eyes of diabetic patients, in comparison to other patients of I group. CONCLUSIONS: Additional procedures, especially releasing of posterior synechiae are correlated with most often early complications as hematoceles, hyphema in anterior chamber, exudate or fibrinous reaction. Cardiovascular disorders are associated with non stability of choroidal circulation, that with post-operative hypotony may correlated with choroidal detachment. In patient with non-insulin-dependent type II diabetes mellitus without diabetic retinopathy, fibrinous reaction or inflammatory exudate, clinical symptoms of blood-aqueous humor barrier damage were not observed in every case.

Cardiovascular Diseases↗
PubMed2005

[Subconjuctival application of 5-fluorouracil (5-FU) following surgical treatment of glaucoma with deep sclerectomy--indications, complications and initial evaluation of effectiveness].

PURPOSE: 5-FU is an antimetabolite which increases efficacy of deep sclerectomy by inhibiting subconjuctival fibrosis and fibroblast proliferation. The objective of the study was to analyze glaucoma patients who had undergone sclerectomy and in a post-surgery period required subconjuctival 5-FU injections. MATERIAL AND METHODS: Out of 120 patients who had undergone deep sclerectomy between January through November 2004, 17 were included in the study since they required subconjuctival 5-FU injections in a post-operative period. The analysis comprised of: (1) indications for antimetabolite administration; (2) time that elapsed from the surgery to the first antimetabolite administration; (3) mean dosage; (4) complications observed; and (5) initial evaluation of the treatment. RESULTS: In 13 patients (76.4%), the indication for 5-FU application was persistent intraocular pressure exceeding 15 mmHg; in one patient (5.8%), the 5-FU treatment was started due to an abrupt increase of the pressure from hypotony; in 6 subjects (35.2%), it was the thickening and vascular dilatation in the filtering bleb; in one subject (5.8%) encapsulated filtering bleb. Mean time of administering 5-FU was between the 2nd and 3rd week following surgery. Mean number of injections applied was 3.7 (18.5 mg 5-FU). The following complications were encountered: corneal superficial punctuate keratopathy (6 subjects), choroidal detachment (1 person), irregular astigmatism (1 person). In most cases IOP was well controlled by the end of the follow-up period (< or = 15 mmHg). CONCLUSIONS: 5-FU is safe and does not increase the perioperative risk, and has turned out to be effective in most cases of increased scarring in the filtering bleb site.

Aged↗
PubMed2005

[The present role of prostaglandin analogues in the medical treatment of glaucoma].

Therapy with prostaglandin analogues (PGA), a novel class of intraocular-lowering medications, represents a safe and very effective pharmacologic method of treating patients with glaucoma and ocular hypertension. The convince dosing regimen, once-daily, higher efficacy and higher systemic safety profile seen with PGA compared with beta-blockers caused that these agents have been approved by regulatory bodies for both the first-line and adjunctive therapy. Short, retrospective analysis of the medical treatment of glaucoma in the Ophthalmology Clinic of Military Health Service Institute in Warsaw, in 2003-2004, was presented.

Adrenergic beta-Antagonists↗
PubMed2004

[Monitoring of blood pressure during phacotrabeculectomy].

PURPOSE: To evaluate systolic and diastolic blood pressure during phacotrabeculectomy performed under regional anaesthesia with retrobulbar block and intravenous analgosedation with midazolam and fentanyl. MATERIAL AND METHODS: 68 patients were involved into the study: I Group: 37 patients with chronic cardiovascular and metabolic diseases: 22 women and 15 men (45 operations), mean aged 72.02 years, mean weight 73.4 kg, II Group: 31 patients without additional diseases: 20 women and 11 men (44 operations), mean aged 70 years, mean weight 68.9 kg. Systolic and diastolic arterial blood pressure was recorded at 5-minute intervals throughout the intraoperative period and anesthetist intervened medically when necessary. RESULTS: In I Group statistically significant mean systolic BP decrease was observed in 5 and 20 minutes after injection of midazolam and fentanyl and mean diastolic BP decrease was observed in 5 and 15 minutes after analgosedation. In II Group statistically significant mean systolic BP decrease was noted in 5 minutes and mean diastolic BP decrease in 5 and 35 minutes. During phacotrabeculectomy mean systolic and diastolic BP was statistically higher in I group. In I group 12 patients and in II group 4 patients required additional antihypertensive drug. CONCLUSIONS: Regional anaesthesia with retrobulbar block and intravenous analgosedation provides hemodynamic stability. Patients with cardiovascular and metabolic diseases required acute observation during phacotrabeculectomy.

Aged↗
PubMed2004

[Mycotic lacrimal canaliculitis--cases report].

Mycotic lacrimal canaliculitis is a rare eye disease. Overuse of antibiotics and steroids in the treatment of eye infections is a very serious risk factor. Initial diagnosis of the mycotic infection may be difficult, thus infection may lasts for months. Chronic conjunctivitis, itching, burning sensations, poor response to the treatment may suggest a suspicion of the mycosis. In our paper we report two cases of the mycotic lacrimal canaliculitis, diagnosis and treatment. We could not culture fungal colonies, but we have found fungal structures in direct microscopic detection during the examination of deposits found in the canaliculi. In our opinion it is important to consider fungal infections during the treatment of chronic eye disorders.

Actinomycosis↗
PubMed2004

[Optic nerve damage in multiple sclerosis patients].

PURPOSE: The aim of the work was to catch the type of damage of optic nerve in the group of patients with multiple sclerosis. MATERIAL AND METHODS: The examinations were held on 77 eyes of 40 patients with multiple sclerosis. Among them 11 patients had previous optic neuritis, 29 have not problems with vision. The examination was conducted by CSV-1000 contrast test depict on contrast sensitivity function and anomaloscopy AN-69 appointing coefficient eta and threshold of red, green and blue hue. RESULTS: As a result, two groups of selective damage and one of non-selective eyes were obtained. In 5 eyes (6.5% examined group eyes) were selective damage of contrast sensitivity in 18 cdg connected with increased threshold for blue hue. The second group of 4 eyes (5.2% examined eyes) were characteristic by damage of contrast sensitivity in 12 cdg and increased threshold of red hue on the border of probable protanomaly. The rest 60 eyes (77.9% the examined group) were non-selective in psychophysical tests. In the eyes of that group were stated non-specific dyschromatopsy connected with equal decrease of contrast sensitivity function, with the tendency to serious changes in high spatial frequency. CONCLUSIONS: Psychophysical tests enable early diagnosis and monitoring of optic nerve damage in multiple sclerosis patients.

Adult↗
PubMed2004

[Surgical treatment of posttraumatic lower canaliculus interruption and results of treatment estimation].

The authors present the method of surgical treatment of posttraumatic lower canaliculus interruption using intubation through upper lacrimal canaliculus. The lacrimal system was intubated through the upper lacrimal canaliculus with a silicone drainage system for 6 weeks. The results were estimated on a base of dacrocystography and scyntygraphy of lacrimal system after 6 month. The presented surgical treatment is both easy for a beginning surgeon and brings good functional results.

Adult↗
PubMed2003

[Terson syndrome--case reports].

The authors described general clinical signs and pathology in eye examination in three patients with Terson syndrome. From this group only one patient recovered. In this case the early eye fundus examination allowed doctors to make the proper diagnosis and led to neurosurgical intervention, just in time.

Adult↗
PubMed2003

[Physiological basis of visual acuity measurement].

The paper presents information about types of acuity tasks, visual acuity limitations and contrast sensitivity function. Measurements of resolution acuity may be interpreted as estimates of spatial density of the mosaic of photoreceptors and ganglion cells of the living human eye. Physiological basis such as Raleigh's criteria, sampling theory and filtering theory of visual resolution are described.

Form Perception↗
PubMed2003

[The eye as an effector of allergic reaction].

In this work the symptoms of allergic diseases of the eye were shortly described. The role of mast cells, eosinophils and lymphocytes taking part in allergic reaction was presented. The cellular mechanisms which lead to symptoms of allergic diseases of the eye were discussed. Histopathological changes in the eye tissues and their clinical importance were taken into consideration. The analysis of allergic symptoms of the eye on the basis of the knowledge of pathophysiological processes gives important information both for ophthalmologists and allergologists.

Cytokines↗
PubMed2003

[Surgery for involutional ectropion--case report].

In this paper authors described methods of surgery in involutional ectropion, surgical anatomy and changes in the lower eyelid due to aging. The surgical treatment of advanced involutional ectropion and its results is presented.

Aged↗
PubMed2003

[Formation of congenital anomalies of the optic disc. Part II. Congenital anomalies of the optic disc with inappropriate disc size].

Embryological conditions, each of fifth congenital anomalies of the optic disc from the group of anomalies of inappropriate optic diameter was described. Few available epidemiological data were given. The influence of medications, drugs, intoxications, as well as premature birth on genesis of congenital anomalies was taken into consideration. Malformation of central nervous system was introduced together with clinical syndromes related to congenital anomalies of the optic disc indicating the genetic condition.

Coloboma↗