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Biomedical subjects

Marcelo Ribeiro

Publications and source records attributed to Marcelo Ribeiro.

5 recordsLinked to original sources
PubMed2006

[Clinical topographic findings in glioblastoma multiforme and the relation with motor impairment].

UNLABELLED: Glioblastoma multiforme (GBM) is the glial tumor with the highest grade of malignity. It mainly affects the cerebral hemispheres, presenting general or focal signs and symptoms, which depend on the size, the location of the lesion and rate of growth of the tumor. OBJECTIVE: To analyze the relationship between motor impairment and GBM topography. METHOD: We studied 43 cases of GBM, related to the age, gender, localization and motor impairment. RESULTS: The occurrence of the tumor was preponderant in adults (mean age 55 years old), men (55.82%), and frontal lobe (approximately 40%). The principal motor impairment was hemiparesis, with the exception of 2 cases in the frontal lobe, 2 temporal, 1 parietal, 1 occipital and 1 frontotemporal. CONCLUSION: The clinical-topographic findings lead to consider the infiltrative effects (broad lesions) are responsible for the motor impairment rather than compressive effects (located lesions).

Adult↗
PubMed2006

Causes of death among crack cocaine users.

OBJECTIVE: The study accompanied 131 crack-cocaine users over a 5-year period, and examined mortality patterns, as well as the causes of death among them. METHOD: All patients admitted to a detoxification unit in Sao Paulo between 1992 and 1994 were interviewed during two follow-up periods: 1995-1996 and 1998-1999. RESULTS: After 5 years, 124 patients were localized (95%). By the study endpoint (1999), 23 patients (17.6%) had died. Homicide was the most prevalent cause of death (n = 13). Almost one third of the deaths were due to the HIV infection, especially among those with a history of intravenous drug use. Less than 10% died from overdose. CONCLUSIONS: The study suggests that the mortality risk among crack cocaine users is greater than that seen in the general population, homicide and AIDS being the most common causes of death among such individuals.

Acquired Immunodeficiency Syndrome↗
PubMed2005

[Services organization for the treatment of alcohol dependence].

The problems related to the consumption of alcohol vary along a gravity continuum. Such a characteristic requests the construction of treatment services that assist to the needs in each one of these situations. Besides, the economical and cultural context of a given community covers the patient of particularities that need to be considered by the service of treatment. This way, the organization of services for the treatment of the dependence of the alcohol should begin for the determination of the structure interns of the institution and its place inside of the net of available attention. The whole construction should be based on the needs of the population-objective (obtained by diagnostic evaluations) and implemented with evaluations and constant monitoring of the wanted impact. Presently, manuals and guidelines available online aid and facilitate the execution of these actions.

Alcoholism↗
PubMed2004

High mortality among young crack cocaine users in Brazil: a 5-year follow-up study.

AIMS: Follow-up studies show that smokers, alcoholics and heroin addicts have high mortality rates, but there is little information on crack users. We have investigated the mortality rate among this population, including its risk factors and causes of death. DESIGN: A 5-year follow-up study. PARTICIPANTS AND SETTING: A cohort of 131 crack-dependent patients, admitted to a public detoxification unit in São Paulo between 1992 and 1994. MEASUREMENTS: Data collected from a structured personal interview and from a review of patients' hospital records, confirming the deaths from records held at the Municipal Offices. FINDINGS: Of the 124 (94.6%) patients located, 23 (18.5%) had died (a mortality ratio of 7.6). Homicide was the most common cause of death (n = 13). Observed mortality rate, adjusted for age and sex, was 24.92 per 1000, while the expected all-cause mortality rate in São Paulo, also adjusted for age and sex, was 3.28 per 1000, giving an excess mortality rate of 21.64 per 1000. Survival analysis showed that the probability of being alive 5 years post-treatment was 0.80 (95% CI = 0.77-0.84). Cox's proportional hazards regression showed three factors predicted mortality: history of intravenous drug use (hazard ratio 3.28, 95% CI 1.42-7.59), unemployment at index admission (hazard ratio 3.48, 95% CI 1.03-11.80) and premature discharge from index admission (hazard ratio 2.21, CI 0.94-5.18). CONCLUSIONS: Community-based and tailored interventions should be considered to improve those patients' social support and permanence in treatment.

Adult↗