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Biomedical subjects

Marcela Ganly

Publications and source records attributed to Marcela Ganly.

2 recordsLinked to original sources

Comparison of laser epithelial keratomileusis with and without the use of mitomycin C.

PURPOSE: To analyze the results of prophylactic intraoperative use of mitomycin C (MMC) in laser epithelial keratomileusis (LASEK). METHODS: A retrospective analysis of 30 LASEK cases that received MMC 0.02% intraoperatively (MMC group) was performed and compared to the results obtained in 28 LASEK cases not receiving MMC (no MMC group). Mitomycin C was placed in contact with the ablation zone for 75 seconds with an imbibed microsponge. Both groups received postoperative fluorometholone for 3 months. Preoperative spherical equivalent refraction was -5.72 +/- 2.82 diopters (D) in the MMC group and -5.81 +/- 2.74 D in the no MMC group. Best spectacle-corrected visual acuity was 0.88 +/- 0.12 in the MMC group and 0.88 +/- 0.13 in the no MMC group. RESULTS: Spherical equivalent refraction at 6 months postoperatively was +0.11 +/- 0.13 D in the MMC group and +0.09 +/- 0.37 D in the no MMC group. Best spectacle-corrected visual acuity was 0.90 +/- 0.13 in the MMC group and 0.88 +/- 0.13 in the no MMC group. Uncorrected visual acuity (UCVA) > or = 20/40 was obtained in 93.3% of cases in the MMC group and in 89.3% of cases in the no MMC group; UCVA > or = 20/25 was achieved in 76.6% of cases in the MMC group and in 71.4% of cases in the no MMC group. Haze incidence for the MMC group was: trace: 0%, Grades I: 0%, II: 0%, III 0%, IV: 0%, and for the no MMC group: trace: 17.9%, Grades I: 3.6%, II: 0%, III: 0%, IV: 0%. A statistically significant difference (P<.001) was noted in haze intensity between the MMC group and no MMC group. CONCLUSIONS: Prophylactic use of intraoperative MMC in LASEK significantly decreases haze incidence.

Adult↗

Phacoemulsification using the burst mode.

PURPOSE: To compare the amount of ultrasound (US) energy required for burst mode and pulse mode during nuclear fragment emulsification. SETTING: Instituto de la Visión, University of Buenos Aires, Buenos Aires, Argentina. METHODS: The ultrasound time (UST) and effective US power (USP) used by 2 surgeons were retrospectively compared. Nuclear fragments were emulsified using the pulse mode in 82 cases (Group 1) and the burst mode in 118 cases (Group 2). The 2 groups were divided according to nuclear hardness: 0 to 2+ (subgroups 1a and 2a) or 3+ to 4+ (subgroups 1b and 2b). The difference in nuclear hardness between Groups 1 and 2 was not statistically significant. RESULTS: The mean UST and USP were, respectively, 1.64 minutes +/- 0.98 (SD) at 10.53% +/- 4.46% in subgroup 1a and 0.56 +/- 0.46 minutes at 10.51% +/- 5.80% in subgroup 1b. The respective means were 2.94 +/- 1.36 minutes at 15.14% +/- 4.49% in subgroup 2a and 0.75 +/- 0.52 minutes at 10.04% +/- 3.12% in subgroup 2b. The differences between subgroups were statistically significant except between subgroups 2a and 2b. CONCLUSION: The burst mode increased US efficiency, especially when used for hard cataracts.

Aged↗