A Synthetic Pore-Mediated Transmembrane Transport of Glutamic Acid This work is supported by a grant from the National Institutes of Health (Grant: GM52190).
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Biomedical subjects
M. Reza Ghadiri
Publications and source records attributed to M. Reza Ghadiri.
Self-Assembling Cyclic Peptide Cylinders as Nuclei for Crystal Engineering This work was supported in part by the Office of Naval Research and the National Institutes of Health (GM 52190). We thank R.K. Chadja for crystallographic analysis and N. Kresge for assistance with computer graphics representations.
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Self-Assembling Organic Nanotubes.
Hollow tubular structures of molecular dimensions perform diverse biological functions in nature. Examples include scaffolding and packaging roles played by cytoskeletal microtubules and viral coat proteins, respectively, as well as the chemical transport and screening activities of membrane channels. In the preparation of such tubular assemblies, biological systems make extensive use of self-assembling and self-organizing strategies. Owing to numerous potential applications in areas such as chemistry, biology, and materials science considerable effort has recently been devoted to preparation of artificial nanotubular structures. This article reviews design principles and the preparation of synthetic organic nanotubes, with special emphasis on noncovalent processes such as self-assembly and self-organization.
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