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Biomedical subjects

M Zuckerman

Publications and source records attributed to M Zuckerman.

At least 55 records · Page 3Linked to original sources
PubMed1996

Beliefs in realistic and unrealistic control: assessment and implications.

Scales were constructed to measure perceived control over controllable events (realistic control) and perceived control over uncontrollable events (unrealistic control). Internal reliability, test-retest reliability, and discriminant validity of both scales were adequate. Study 1 measured perceived personal control over hassles that judges rated on general controllability. For hassles very high in controllability, perceived personal control was related to belief in realistic control but not to belief in unrealistic control; for hassles very low in controllability, perceived personal control was related to belief in unrealistic control but not to belief in realistic control. Study 2 showed that participants high in unrealistic control belief (but not those high in realistic control belief) persevered more on a task that was in part uncontrollable. Study 3 showed that the combination of low realistic control belief and high unrealistic control belief predicted poorer future health, particularly for participants who have reported the experience of many negative events and/or hassles. The conditions under which unrealistic control results in maladaptive outcomes are discussed.

Adaptation, Psychological↗
PubMed1996

Hepatobiliary kinetics of technetium-99m-IDA analogs: quantification by linear systems theory.

UNLABELLED: A compartmental model describing the extraction and disposition of 99mTc-acetanilidoiminodiacetic acid (IDA) compounds by the liver has been applied to 5 adult patients admitted for cholecystitis investigations and 29 jaundiced infants the majority of whom were clinically differentiable into neonatal hepatitic and biliary atretic groups. METHODS: In each case kinetic rate constants were calculated to describe hepatocyte extraction of 99mTc-IDA structural analogs from blood pool (k21) and subsequent elimination (k3) of this compound into biliary tract. Also modeled was the reverse-binding constant (k12) describing the return of such radiotracer to the systemic circulation and the blood fraction (f) which accounted for the composite vasculature forming a matrix in the liver. RESULTS: It was shown that these indices could be used to determine accurate compartmental mean residence times (MRT(c)s) for each patient by correlation with values obtained by deconvolutional analysis and independent measurement of leading edge parenchymal transit times. For the adult patients the following indices, typical of good hepatocyte function, were derived: k21 = 0.933 +/- 0.488 min-1, k12 = 0.0277 +/- 0.0340 min-1, k3 = 0.1610 +/- 0.0531 min-1, f = 0.3519 +/- 0.3048 and MRTc = 11.19 +/- 3.13 min. Analysis of the pediatric group revealed no significant differences in their respective MRT(c)s. However, significant differences in the extraction (p < 0.01) and excretion (p < 0.001) coefficients were prominent. CONCLUSION: This method can be applied to provide accurate and meaningful intercompartmental rate parameters and MRT(c)s for adults, nonobstructed and obstructed infants.

Aged↗
PubMed1994

Causality orientations, failure, and achievement.

Two studies examined similarities between Deci and Ryan's (1985) causality orientations theory and Dweck and Leggett's (1988) social-cognitive theory of achievement. Study 1 examined the conceptual similarity between the individual difference measures central to the two theories. It was shown that autonomous college students are likely to adopt learning goals and report high confidence in their academic abilities; controlled students are likely to adopt performance goals and to report high levels of confidence in their ability; and impersonal students are likely to possess the classic helpless pattern of performance goals and low confidence in their academic abilities. Study 2 examined whether causality orientations, like Dweck's measures of goals and confidence, moderate the impact of failure feedback on motivation as measured in persistence and performance. The results suggested that autonomous individuals respond to failure in a mastery-oriented fashion, whereas impersonal individuals respond in a helpless manner. The response of controlled individuals to failure parallels that of people described as ego-involved or reactive.

Achievement↗
PubMed1994

Rickets in very-low-birth-weight infants born at Baragwanath Hospital.

Disturbed mineral and bone metabolism has been reported to occur frequently in very-low-birth-weight infants fed breast-milk during the first 3 months of life. This study was designed to assess the prevalence of disturbed mineral homeostasis in a breast-milk-fed very-low-birth-weight population at Baragwanath Hospital and to determine whether the addition of a preterm infant formula to the feeds would reduce this prevalence and increase the rate of weight gain. Fifty-three neonates weighing less than 1 200 g at birth were monitored for weight gain, growth and biochemical and radiological evidence of metabolic bone disease at 2-weekly intervals during hospitalisation and for 18 weeks after discharge. The infants were randomised at 2 weeks of age to receive either breast-milk only, or a combination of breast-milk and a premature formula containing 550 mg calcium and 300 mg phosphorus. All infants received 800 IU vitamin D daily from day 14. Weight gain and growth were similar in both groups. Calcium and phosphorus intakes were higher in the mixed feeding group, but did not affect serum mineral levels. Radiological rickets was uncommon in both groups although periosteal reactions and osteopenia occurred frequently and with similar prevalences. Vitamin D deficiency was not found to be a problem. In conclusion, overt rickets is not a major problem in very-low-birth-weight infants born at Baragwanath Hospital, although biochemical abnormalities occur frequently.(ABSTRACT TRUNCATED AT 250 WORDS)

Anthropometry↗
PubMed1993

Rapid response of AIDS-related bacillary angiomatosis to azithromycin.

A 28-year-old male with AIDS and a CD4 cell count of 100/mm3 presented with fever, hepatosplenomegaly, weight loss, and multiple, polypoid, angiomatous lesions on his face. It was determined by means of biopsy that the lesions were due to bacillary angiomatosis. The patient was treated with oral azithromycin (1 g daily as a single dose). Rapid resolution of the skin lesions was noted. After 1 week of therapy, diminution in the size of the liver and spleen was noted. The only significant side effect noted was diarrhea, which was controlled with symptomatic therapy.

AIDS-Related Opportunistic Infections↗
PubMed1993

Beyond personality impressions: effects of physical and vocal attractiveness on false consensus, social comparison, affiliation, and assumed and perceived similarity.

We examined the effects of target persons' physical and vocal attractiveness on judges' responses to five measures: false consensus (the belief that the target shares one's behavior), choice of targets as comparison others, affiliation with targets, assumed similarity (similarity between self-ratings and ratings assigned to targets), and perceived similarity (direct questions about similarity). Higher physical attractiveness and higher vocal attractiveness were both related to higher scores on all variables. The effect of one type of attractiveness was more pronounced for higher levels of the other type of attractiveness. The joint effect of the two types of attractiveness was best described as synergistic, i.e., only targets high on both types of attractiveness elicited higher scores on the dependent variables. The effect of physical attractiveness on most dependent variables was more pronounced for subjects who were themselves physically attractive. The synergistic effect (the advantage of targets high on both types of attractiveness) was more pronounced for judges high in self-monitoring. The contribution of the study to the literature on attractiveness stereotypes is discussed.

Adult↗
PubMed1993

P-impulsive sensation seeking and its behavioral, psychophysiological and biochemical correlates.

Impulsive unsocialized sensation seeking (ImpUSS) is a major factor discovered in factor analyses of scales used in psychobiological research. It is strongly convergent with Eysenck's P dimension and conscientiousness in the 'big five'. The components of the dimension and the P scale, have been validated as correlates of various kinds of disinhibited behaviors, criminality, sexuality, and substance use and abuse. ImpUSS is related to a failure in passive avoidance learning, probably as a function of impulsivity and attention to reward stimuli. Psychophysiological markers for the trait include strong orienting and weak defensive reflexes and an augmenting, rather than reducing, of cortical reaction to intense stimuli. At the neurochemical level the trait is related to low levels of monoamine oxidase (MAO) and the neurotransmitters norepinephrine and serotonin, and theoretically high levels of dopaminergic activity. The trait components have high heritabilities for a personality trait.

Humans↗
PubMed1992

Sensation seeking and selective attention: focused and divided attention on a dichotic listening task.

Differences in selective attention as a function of sensation seeking, extraversion, neuroticism, and psychoticism were examined in 108 undergraduates using a dichotic listening task. Dependent measures included shadowing performance, reaction times to a secondary light task, target detection, and recall. The results suggested that high sensation seekers have better focused attention than low sensation seekers, and these effects were strongest on the 1st trials of the shadowing tasks. High sensation seekers did not attend differently than low sensation seekers to words related to their interests (sexual, violent, or drug related). Extraversion was associated with greater recall of these kinds of words, although there were no overall differences in selective attention as a function of Eysenck's dimensions. The role of arousal in personality and attention is discussed, particularly in regard to the response of sensation seekers to task novelty.

Adult↗
PubMed1991

Cross-channel effects of vocal and physical attractiveness and their implications for interpersonal perception.

Judges' ratings of senders' vocal attractiveness from face-plus-voice (F+V) cues were influenced by senders' physical attractiveness, and ratings of senders' physical attractiveness from F+V cues were influenced by senders' vocal attractiveness. This occurred even when judges were warned not to pay attention to face when rating vocal attractiveness and not to pay attention to voice when rating physical attractiveness. Instructions to judge attractiveness without being told which channel to attend to resulted in ratings influenced by both vocal and physical attractiveness of senders. Because of cross-channel effects, F+V attractiveness ratings should be more highly related to F+V personality impressions than attractiveness ratings based on only face or only voice. The results supported this hypothesis. Implications of cross-channel effects for research on the attractiveness stereotype were discussed.

Esthetics↗
PubMed1991

Fulminant hepatitis in children: report of 12 cases.

Twelve cases of childhood fulminant hepatitis seen over a 4-year period are described. Six had hepatitis A, five hepatitis B and one non-A non-B hepatitis. Encephalopathy, the cardinal feature of fulminant hepatitis, was usually evident within 2 weeks of onset of illness, and the median duration of illness in fatal cases was 19 days. Deep jaundice, prolongation of the prothrombin time and raised serum ammonia were invariable. Eight children died and the four survivors were critically ill before recovering. Acute viral hepatitis is generally a benign illness in childhood. Although infrequently recorded, fulminant hepatitis may, however, ensue and is associated with a high mortality.

Acute Disease↗