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Biomedical subjects

M Zicot

Publications and source records attributed to M Zicot.

At least 37 records · Page 2Linked to original sources

Application of a simplified physical model to the plethysmographic study of the leg venous outflow.

We describe a simplified physical model of the leg venous outflow. It features an apparent compliance C and outflow resistance R. The venous volume accumulated during a venous occlusion discharges after the release of the compression following an exponential curve (T = time constant = RC). This model fits the curves obtained by strain gauge plethysmography in normal legs and in limbs suffering from chronic venous obstructions. The values for R, C and T are calculated from the plethysmographic measurements. The limbs with chronic obstructions differentiate themselves from the normal mainly by an increase of R but some limbs show values close to normal likely due to a compensation (collaterals or partial recanalization). T (prolonged) and C (decreased) are less affected by chronic venous obstructions. The diagnostic score of this mode of analysis is better than the usual graphic determination of the maximum venous outflow (MVO).

False Positive Reactions↗

[Study of iliac arterial axes by Doppler ultrasonography during hyperemia induced by walking and arterial occlusion].

We measure the pulsatility index (IP) of the femoral artery by CW-Doppler on 51 limbs, after a treadmill exercise and during a postischemic reactive hyperemia. The pulsatility index (IP) is calculated from the analogic curve produced by a CW-Doppler velocimeter (DUD 400) following a previous work (3). The walking test is carried on until an intermittent caludication is achieved. The ultrasonic curve is recorded after two minutes of recuperation. The hyperemic test follows the application for one minute of a suprasystolic thigh arterial tourniquet. A significant iliac lesion is suspected when IP drops below 1.2 after exercise (3). The IP levels measured during both tests (exercise and reactive hyperemia) are well correlated (r = 0.89). The concordance is achieved among 46 limbs. There is no agreement in 5 cases. IP is lower (less than 1.2) during the reactive hyperemia and higher after exercise (greater than 1.2) in 4 cases. The walk test demonstrates a lesion when the postischemic test is negative in one single case. The CW-Doppler ultra sonography of the femoral artery after the application of a tourniquet is therefore a sensitive method to investigate the iliac flow tract. This technique may be applied on patients enable to walk on the treadmill.

Aortic Diseases↗

[Sequelae of unilateral deep venous thrombosis in plethysmography of the calf].

Twenty four patients suffering from unilateral venous disturbances revealed by Doppler and secondary to a deep venous thrombosis were examined. The calf venous haemodynamics was analyzed by use of a strain-jauge plethysmograph. We determined the increase in venous volume due to the inflation of a thigh pneumatic cuff (pressure at 20, 40 and 60 mm Hg; delta V20, delta V40, delta V60). The maximal venous output (Vout) was measured after a quick release of the 60 mm Hg pressure. The maximal venous drainage (VMM) was assessed during a rhythmic exercise (tiptoeing) while standing; delta V20, delta V40 and delta V60 were nearly constantly reduced on the abnormal side (t of Student respectively 3.49; 6.09 and 5.07). Vout dropped proportionaly to delta V60. Some abnormalities due to valvular insufficiency were frequently present in the beginning of the inflation curve at the level of the abnormal limbs. VMM was nearly always largely decreased on the affected side (t = 5.43). The unilateral flow disturbances displayed by the Doppler were regularly going with abnormalities of the capacitive system, well demonstrated by comparison with the non-affected limbs.

Blood Pressure↗

[Intermittent claudication. Introduction to clinical diagnosis].

The history and the physical examination are still at the basis of the approach of the patient suffering from intermittent claudication. The history makes clear the specific symptom and its localization. The evolution of the disease, the social and professional handicap are defined. Other troubles and other localizations of the vascular disease are recognized and the nature of the risk factors etablished. The physical examination indicates the pattern and the distribution of the vascular lesions and orientates the pathogenic investigations. A rough assessment of the insufficiency of the cutaneous and muscular circulation is also possible.

Humans↗