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Biomedical subjects

M Yokogawa

Publications and source records attributed to M Yokogawa.

At least 37 records · Page 2Linked to original sources

Eosinophilic meningitis: a suspected case of angiostrongylosis found in Shizuoka Prefecture, Honshu, Japan.

A patient with eosinophilic meningitis in Shizuoka Prefecture, Honshu, Japan had nausea, vomiting and headache on admission; laboratory examinations revealed leukocytosis with eosinophilia. Eight days later neck stiffness appeared. Lumbar puncture showed an increase of the initial pressure in association with eosinophilic pleocytosis in the spinal fluid. The possibility of angiostrongylosis was considered because the patient had eaten raw slugs for 4 years as a remedy for lumbago. Although the serum contained cross-reactive antibodies against Toxocara canis, positive reactions to Angiostrongylus cantonensis antigens were observed in all of the immunological tests made. These observations, together with results of epidemiological studies in Honshu carried out by other investigators, suggest that the present case of eosinophilic meningitis may have been caused by A. cantonensis. One previous case has been reported from Honshu Island, Japan.

Adrenal Cortex Hormones↗

Immunoglobulin E: raised levels in sera and pleural exudates of patients with paragonimiasis.

Serum IgE concentrations of patients with paragonimiasis were determined by a radioimmunosorbent test. The mean concentration was 3,462.3 IU/ml in a group of 13 cases of paragonimiasis miyazakii in which patients showed clinical symptoms and/or positive immunological diagnostic tests, and 1,026.6 IU/ml in a control group of 13 individuals who had eaten uncooked freshwater crabs, Potamon dehaani, but had been found to be free from the infection. Moreover, the IgE level of the pleural exudates obtained from four patients with paragonimiasis miyazakii on the day of bleeding or within several days after was significantly higher than that of their sera, ranging between 4,200 IU/ml and 10,000 IU/ml. This was true also in a case of paragonimiasis westermani. Sera and pleural exudates of patients with both forms of paragonimiasis were applied to immunosorbent columns of Sepharose 4B beads coupled with saline extracts of Paragonimus miyazakii, P. weetermani, or P. ohirai. IgE eluted from the corresponding column was considered to be specific, being around 5% to 10% of the total IgE.

Adult↗

Review of prevalence and distribution of schistosomiasis in Japan.

There has been a temporary increase in schistosomiasis japonica after World War II in each of the known endemic areas, but a national control programme, including use of molluscicides, lining irrigation ditches through rice paddies with concrete and the reclamation of swampy areas by drainage and filling, begun around 1950, drastically reduced the prevalence and distribution of the disease. It can be said that these measures together with improvements in agricultural techniques, mechanization of farming and also socioeconomic factors such as improvements in the living standards of the inhabitants and urbanization have brought about a rapid decrease in schistosomiasis in Japan.

Animals↗

[Paragonimiasis].

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History, 19th Century↗

[Paragonimiasis].

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Anti-Infective Agents↗