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Biomedical subjects

M Wybier

Publications and source records attributed to M Wybier.

At least 37 records · Page 2Linked to original sources
PubMed1997

[Myositis ossificans circumscripta and its variants].

Myositis ossificans circumscripta (MOC) is a benign proliferation of fibrous tissue with large amounts of bone within soft tissues. Its clinical and radiological course is described and the value of CT and MR imaging is emphasized. Differential diagnosis includes soft tissue hematoma, infection or tumor. Florid reactive periostitis of the phalanges, turret exostosis, bizarre periosteal osteochondromatous proliferation in the hand and fibro-osseous pseudotumor of the digits are also described.

Biopsy↗
PubMed1997

[Diagnosis of calcified deposits in soft tissues].

Calcific deposit within soft tissues is frequently a clue for diagnosis. The radiological analysis of a calcific deposit within soft tissues includes the following aspects: the basic structure of the calcification, the grade of differentiation of the calcification, the site of the calcification, the number of calcific deposits, the shape of the calcification, the changes in the adjacent non-calcified soft tissues and in the adjacent bone, the course of the clinical signs, the course of the radiological abnormalities.

Calcinosis↗
PubMed1997

[Secret information provided by lumbosacral myelography].

The authors emphasize the misleading images of lumbar myelography encountered in common vertebral diseases: disk disease, posterior interapophyseal joint diseases, degenerative and narrow spinal canal, in which dynamic views in the upright position represent the most original contribution of lumbosacral myelography as compared to new techniques. The authors also describe the postoperative appearances observed on lumbosacral myelography and some rarer diseases which must not be missed, such as epidural arachnoid cysts and epidural lipomatosis.

Angiography↗
PubMed1995

[Imaging of the lumbar spine after diskectomy].

The radiological investigation of persistent or recurrent sciatica after lumbar diskectomy essentially consists of demonstrating recurrent disk herniation. Comparison between plain and contrast enhanced CT or MR examinations at the level of the diskectomy is the main step of the radiological survey. The meanings of the various radiological findings are discussed. Other lesions that may induce persistent sciatica after lumbar diskectomy include degenerative narrowing of the lateral recess, spinal instability, stress fracture of the remaining neural arch, pseudo-meningomyelocele after laminectomy.

Diskectomy↗
PubMed1995

[Vertebral vacuum phenomena].

The spinal vacuum phenomenon is a collection of gas within the disk space, the vertebral body, the apophyseal joint or the spinal canal. The intradiscal vacuum phenomenon is frequently observed in degenerative disk disease and crystal-induced diskopathy. This has obvious significance to the radiologist, who, on observing a narrowed disk space or collapsed vertebral body, might otherwise consider infectious or neoplastic spondylitis, a likely possibility. The presence of vacuum phenomenon militates against the diagnosis of infection or tumor.

Chondrocalcinosis↗
PubMed1995

[Current imaging of spondylolisthesis by isthmic lysis].

Unilateral spondylolytic spondylolisthesis may cause lateral tilt of the overlying spinous processes towards the normal isthmus on PA views. Bilateral spondylolytic spondylolisthesis is generally located at the L5-S1 level. The vertebral shift is usually moderate. Instability at the level of spondylolisthesis may be demonstrated by stress lateral views but is uneasy to quantify. In case of sciatica associated to spondylolisthesis, foraminal stenosis is probably the most frequent cause but foraminal compression of the spinal ganglion is difficult to assess on imaging.

Humans↗
PubMed1995

[Lumbar puncture with a fine needle].

26-Gauge fine needle for lumbar puncture allows lower rate and intensity of post lumbar puncture syndrome. This technique drammatically decreases discomfort in patients who undergo myelography and helps in keeping this imaging modality indicated when necessary.

Headache↗
PubMed1995

[Radioguided injection of the lumbar and the first sacral intervertebral foramina].

Lumbar foraminal injection under fluoroscopic guidance is indicated either for a diagnostic purpose to determine which nerve root is painful or for a selective steroid injection. Lumbar foraminal approach is based on that of the posterolateral extradural diskography. Selective puncture of the first sacral foramen under fluoroscopic guidance may be indicated for the treatment of sacral symptomatic meningeal cysts, a very unfrequent lesion.

Adrenal Cortex Hormones↗
PubMed1995

[The puncture of the knee].

Knee puncture for arthrography via a lateral parapatellar approach is described. Direct puncture of the femorotibial space, via a ventral approach, is more painful and should only be used when the lateral parapatellar route is not possible, namely in case of complete suprapatellar plica.

Arthrography↗
PubMed1994

Potentiation of transforming growth factor (TGF-beta 1) by natural coral and fibrin in a rabbit cranioplasty model.

The association of a biodegradable material and a growth factor could be of clinical value for treating bone defects. We therefore tested the association of transforming growth factor beta (TGF-beta 1) in fibrin glue and coral granules to heal skull defects in rabbits. Adult rabbits underwent a double trepanation symmetrically in both parietal bones. Using histomorphometry, we compared bone repair after 1 month in control animals (n = 5) and in animals treated with either TGF-beta 1 as a single injection of 1 microgram in methylcellulose (n = 5) or in fibrin glue (n = 5), or with coral granules in fibrin glue (n = 4) or with coral granules and TGF-beta 1 1 microgram in fibrin glue (n = 5). We measured the diameter of the remaining defect and the surface of the bone growth. TGF-beta 1 without coral in either methyl cellulose or fibrin induced a partial closure of the defect as assessed by a significant decrease in the defect diameter, compared with the control group. However, the association of TGF-beta 1 in fibrin and coral induced an area of the bone growth higher than in any other groups (P < 0.05). Two months after surgery, this triple association induced a better healing of the defect than coral alone or control group. In each group treated with TGF-beta 1, the mineralization rate was increased not only at the treated side but also in the contralateral defect which was untreated, suggesting a diffusion of the growth factor.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗
PubMed1994

[Osteogenesis induced by the combination of growth factor, fibrin glue and coral; towards a substitute of autologous bone graft. An experimental study on the rabbit].

A triple mixture of TGF-beta, fibrin glue and natural coral skeleton granules (madreporic calcium carbonate) was tested in a rabbit bilateral cranioplasty model. Three-dimensional CT scan and histomorphometry demonstrated that, at one month and at two months, this association produced significantly more bone tissue than other associations, especially growth factor or coral alone. The rate of mineralization was significantly increased bilaterally in all animals having received TGF-beta. Coral resorption was also accelerated by growth factor and was replaced by histologically normal bone after two months. We emphasize the potentiation of TGF-beta by fibrin glue and natural coral skeleton and its potential application as a bone substitute.

Animals↗
PubMed1993

[The femoropatellar joint].

Anomalies of the femoropatellar joint are frequent due to the vulnerable anatomical situation of the patella. Any knee abnormality, constitutional as well as acquired, may compromise the precarious dynamic balance existing between external and internal forces applied to the patella.

Arthrography↗
PubMed1992

[Sub-acromio-deltoid bursography].

Subacromio-deltoid bursography may be diagnostic and/or therapeutic. As a diagnostic procedure, it opacifies the bursa, which may be more or less fused. It visualises the superior surface of the cuff, which may be fissured and it demonstrates exaggerated impression of the acromio-coracoid ligament. It is only indicated when arthrography of the shoulder is normal. As a therapeutic procedure, it constitutes a more sensitive test than Neer's test. When it is negative, the diagnosis of anterior conflict is doubtful. The addition of a corticosteroid prolongs the therapeutic effect and facilitates rehabilitation.

Acromioclavicular Joint↗
PubMed1992

[X-ray guided puncture-aspiration of refractory calcifications of the shoulder].

Calcifying periarthritis of the shoulder may have either an acute or a chronic course. In both cases, direct puncture of the calcification shortens the natural history and facilitates and accelerates resorption in 50% of cases. The addition of a small amount of corticosteroid relieves the painful syndrome, with 80% good and very good results. The use of low doses of corticosteroid is particularly important in diabetics, patients with peptic ulcer and sportsmen. The puncture technique and the necessary precautions are described.

Adrenal Cortex Hormones↗
PubMed1992

[Shoulder instabilities. Radiological evaluation].

In case of anteromedial instability of the shoulder, the radiological investigation should start by comparative plain films including glenoid lateral views looking for a lesion of the anteroinferior glenoid margin of the scapula. If plain films are normal, CT arthrography of the shoulder is indicated looking for a lesion of the anteroinferior glenoid labrum. If no traumatic abnormality is present, a plain CT scan may sometimes show glenoid dysplasia, which is frequently bilateral. Posterior dislocation of the shoulder is less common and is obvious on plain films. The inventory of the lesions is established by CT arthrography. In case of multidirectional instability, the radiological investigation determines the preferential direction of instability, generally by means of dynamic manoeuvres.

Arthrography↗
PubMed1992

Facet joint block for low back pain: identifying predictors of a good response.

This preliminary study was conducted to identify a facet joint syndrome in low back pain. Ninety maneuvers and symptoms were compared between patients relieved (responders) and those unrelieved (nonresponders) after intraarticular blocks. Fifty-one patients participated in the study; 11 were excluded from evaluation because of unsuccessful injection into the joints as planned. Of the 40 patients included, 20 had four joints anesthetized, 16 had two joints anesthetized, and four had three joints anesthetized. Twenty-two were responders, 17 of whom had more than 90% relief of pain. Only a few variables were more frequent in the responder group: older age, absence of exacerbation by coughing, relief when recumbent, absence of exacerbation by forward flexion and when raising from this flexion, absence of worsening by hyperextension, and extension-rotation. When four of these seven variables were present in the same patient, sensitivity was 81.8% and specificity 77.8%, but this discriminant power must be evaluated in a new population.

Adult↗
PubMed1992

Lumbar disc herniation. Computed tomography scan changes after conservative treatment of nerve root compression.

In 21 patients with computed tomography-diagnosed lumbar herniated nucleus pulposus, nerve root pain resolved after conservative treatment. A subsequent computed tomography scan was performed 6 months or more after presentation. This follow-up computed tomography scan was compared with the initial one. A definite decrease in size of the herniated nucleus pulposus was observed in 14 patients: disappearance in 5, obvious decrease in 5, and moderate decrease in 4. No definite change was observed in seven patients. Major computed tomography scan changes occurred significantly more frequently in large herniated nucleus pulposus than in small ones (p. less than 0.05). This study suggests that large lumbar herniated nucleus pulposus can decrease and even disappear in some patients treated successfully with conservative care.

Adult↗