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Biomedical subjects

M Wong

Publications and source records attributed to M Wong.

At least 379 records · Page 21Linked to original sources
PubMed1976

Cephalexin compared to ampicillin treatment of otitis media.

Cephalexin was compared to ampicillin for the treatment of otitis media in a randomized study. Bacteriologic diagnosis was sought by needle tympanocentesis in 179 children. No overall statistically significant differences were noted between the two groups; however, 20 patients who received cephalexin had a poor response to therapy whereas only five recipients of ampicillin responded poorly. A significant difference (P less than .05) between the two regimens was noted when Hemophilus influenzae was recovered. Fifty per cent of the children with H. influenzae otitis media who were treated with cephalexin responded poorly; no patients receiving ampicillin had a poor response. Our data suggest that the use of cephalexin monohydrate is not warranted for treatment of otitis media due to H. influenzae even when the isolate proves sensitive to this drug in vitro. In selected patients with otitis media caused by Staphylococcus aureus which is resistant to penicillin, cephalexin may provide effective treatment.

Ampicillin↗
PubMed1975

Optimizing cinefilm.

A system for improving the quality of cinefilm and for maintaining quality control is described. Objective criteria for contrast, resolution, and grain structure were established to measure the effects of varying X-ray dose, f-stop, development temperature, and selection of film and developer. We found that all variables nust be adjusted to maximize the viewing quality and that similar denisty curves can be achieved, independently of the choice of film and developer.

Angiocardiography↗
PubMed1975

Aldosterone-Induced Membrane Phospholipid Fatty Acid Metabolism in the Toad Urinary Bladder.

Aldosterone action in the isolated toad urinary bladder has been studied by incubation of the tissue with several specifically labeled lipogenic precursors. Within 30 min after hormone addition phospholipid synthesis is stimulated; the metabolism of oleic acid is particularly enhanced. Additionally, during this time interval a phospholipid deacylation-reacylation cycle is stimulated by aldosterone.

Acetates↗
PubMed1974

In vivo sampling of cardiac triglyceride from dogs during ethanol infusion.

The feasibility of procuring and analyzing cardiac tissue for triglyceride in vivo was tested in anesthetized dogs. Measurements of triglycerides in samples obtained in vitro confirmed: reproducibility of triplicate analyses of the glycerideglycerol moiety of tissue triglyceride (SEM +/- 2.1%), homogeneity in and between ventricles (SEM +/- 1.8%), and agreement between right endocardial triglyceride and left myocardial triglyceride (difference not significant). Seven dogs received ethanol, 15-30 mg/kg/min, and five dogs received glucose or 0.85% NaCl for 2 hr. Cardiac output and filling pressure were measured from the left ventricle and tissue was taken from the right ventricle with a biopsy catheter before and during infusions. Three to four samples were obtained from each dog; the average weight was 14.4 mg and two to three biopsies were required for each sample. In the ethanol group, triglyceride increased after 15 min and continued to rise; the final triglyceride concentration correlated with the infusion rate. In the glucose-saline group, in vivo triglyceride concentration did not change and did not differ from postmortem triglyceride. Cardiac function declined in the ethanol group and was unaffected in the controls. Thus, multiple in vivo measurements of cardiac lipid are practical and safe and show that ethanol infusions cause early and progressive accumulation of triglyceride in heart muscle.

Animals↗
PubMed1972

Hormonal control of the renal conversion of 25-hydroxycholecalciferol to 1,25-dihydroxycholecalciferol.

Isolated renal tubules from vitamin D-deficient chicks catalyse the in vitro conversion of 25-hydroxycholecalciferol to 1,25-dihydroxycholecalciferol. This conversion is stimulated by 5 x 10(-10) M bovine parathyroid hormone, or by 10(-6) M cyclic AMP. It is inhibited by 10(-9) M porcine calcitonin. It is concluded that these hormonal controls of the synthesis of the renal hormone 1,25-dihydroxycholecalciferol are of particular physiological significance in coordinating the activities of the various organs involved in extracellular calcium homeostasis.

Animals↗
PubMed1971

[Not Available].

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Botany↗