Improved prevention of abdominal wound sepsis by parenteral and topical antibiotics.
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Biomedical subjects
Publications and source records attributed to M Wellsted.
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Four patients are presented who sustained blunt trauma and later developed necrotizing fasciitis in the areas of contusion, associated with the distant locus of sepsis. Three of the cases developed acute renal failure and later died. Early recognition of this condition allows prompt debridement beyond the margins of involved necrotic fascia, followed by wound inspection 8-hourly, and treatment with antibiotics, most recently third-generation cephalosporins, piperacillin, amikacin, and vancomycin.
Two unusual complications related to fibre-optic endoscopy are described. In one case a pneumomediastinum occurred during gastroscopy with no evidence of perforation. The patient was treated conservatively and made an uneventful recovery. The suggested mechanism is that of alveolar leakage resulting from raised intrathoracic pressure. The other is a case of temporomandibular joint dislocation, a complication not previously described.
A case of malignant insulinoma in a Black patient is presented. An investigational protocol is suggested with a discussion of the newer techniques of pancreatic adenoma localization and the therapeutic measures available for the management of malignant islet cell tumours.
A case of torsion of the gallbladder is reviewed. The radiographic features of the case suggest that in future pre-operative diagnosis may be possible with the use of ultrasound and contrast radiography.
A case of a young man with a choledochocele is presented. The entity is rare and symptoms are usually nonspecific. Pre-operative diagnosis is often not made but is usually possible provided both barium study and cholangiography are performed. The clinical presentation and diagnosis are discussed.