A problem arose in a blood bank in which about 10 percent of platelet concentrates (PC) observed at day 1 had a large number of macroscopic aggregates. The aggregates were clumps of platelets that did not go into suspension during preparation of PC. These units were set aside for observation. A maximum of 25 percent were stored on a circular rotator; the remainder were stored on either an elliptical rotator or horizontal shaker. By the end of storage, 6 percent of the units still had a large number of clumps. This percentage was reduced to 2.4 percent, when all clumped units were stored on a circular rotator. The number of clumped units observed at day 1 and at the end of storage were reduced dramatically when the temperature of the laboratory (18-19 degrees C), centrifuge (20 degrees C) and storage environmental chamber (22 degrees C) were increased to 24 degrees C. The units with clumps at day 5 were reduced from 225 (out of 8316) to 25 (out of 7137).

Blood Preservation↗

PubMedDate not supplied

Transformation of plantar verruca into squamous cell carcinoma.

The authors present a case study of a long standing plantar verruca undergoing malignant transformation to a squamous cell carcinoma. This case depicts the rapid change in a plantar verruca of some 20 years' duration without any prior symptomatology. Such malignant change, while rare, can occur and any change in the color, shape, size, or sudden onset of pain in a benign lesion should constitute the consideration of possible malignancy.

Carcinoma↗

PubMedDate not supplied

The private sector. Management and teaching.

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Attitude of Health Personnel↗