Biomedical subjects
Publications and source records attributed to M W Ho.
A marked deficiency of a specific thermolabile beta-galactosidase isoenzyme (pH optimum 3 to 5) was found in liver and kidney tissues of five patients with the Hurler's syndrome (types 1 to 3).
We have demonstrated a tenfold (or greater) reduction of the cleavage of galactose from a mucopolysaccharide and a glycoprotein in generalized gangliosidosis, a lysosomal beta-galactosidase deficiency disease. The bony abnormalities in this disease may be due to defective catabolism of mucopolysaccharides in connective tissue.
A tentative theory of the organism is derived from McClare's (1971) notion of stored energy and Denbigh's (1951) thermodynamics of the steady state, as a dynamically closed, energetically self-sufficient domain of cyclic non-dissipative processes coupled to irreversible dissipative processes. This effectively frees the organism from thermodynamic constraints so that it is poised for rapid, specific intercommunication, enabling it to function as a coherent whole. In the ideal, the organism is a quantum superposition of coherent activities over all space-time domains, with instantaneous (nonlocal) noiseless intercommunication throughout the system. Evidence for quantum coherence is considered and reviewed.
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