Biomedical subjects
Publications and source records attributed to M W Friedman.
Nonhelical mutant cells of Spirillum volutans ATCC 19554 can swim as fast as the helical cells. Consequently, a helical cell shape is not required for motility of this species, and the function of the polar flagellar fascicles is not merely to cause rotation, and therefore translocation, of the corkscrew-shaped cell.
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4 cases of retinal detachment following the use of an intraocular lens have been described. Each offered a different problem in management, the results being satisfactory in 3 out of 4 cases. The ability to dilate the pupil and the clarity of the media, along with the maintenance of the proper position of the lens seem to be the most important factors in the treatment of these cases.
Acute retinal pigment epitheliitis appears to be a specific discrete process of unknown etiology. It is generally unilateral but can be recurrent and can affect both eyes. Eyes in which the disease has run its course exhibit little or no unusual ophthalmoscopic or visual function abnormalities. The actue phase of the disease is localized to the macular area. The lesions are localized in the retinal pigment epithelium as shown by slit-lamp and contact-lens examination, the small lesions more or less surrounding the fovea. They vary from tiny grayish to black spots, which may become surrounded by a lighter halo. Fluroescein angiography is normal in acute phases but the halo-like areas may represent "window defects" with hyperfluorescence in later stages.
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The paper demonstrates that limited cryosurgery combined with scleral buckling in premature infants with acute proliferative retrolental fibroplasia in a procedure which can be extremely successful in the treatment of this devastating disease. Timing for surgical intervention is critical. The indications for the surgical intervention are stated. The continuous monitoring of those infants with retrolental fibroplasia is critical to the success of the operative procedure. Since critical timing for success is involved, a new schedule for ophthalmic examination of the premature infant is proposed. This new schedule differs significantly from that proposed by the American Academy of Pediatrics in 1971. At that time, there was no successful treatment for retrolental fibroplasia. In contrast, we submit that limited cryosurgery combined with scleral buckling is an efficacious form of therapy for this disease.
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