M Vucković | Search PubMed

PubMed1986

Effect of cAMP on cytosol protein phosphorylation in placental tissue of different gestational age.

Phosphorylation of cytosol proteins in placental tissue of different gestational age has been studied. Cytosol protein phosphorylation was stimulated by exogenous cAMP only in term placentae and remained unchanged in first and second trimester placentae. Exogenous proteins, histone and casein, were intensively phosphorylated by cytosol kinases with maximal activities in first trimester cytosol preparations. Exogenous cAMP stimulated histone phosphorylation, but it had no effect on casein phosphorylation. On the basis of the obtained results it can be concluded that endogenous protein phosphorylation in first and second trimester placental cytosol is cAMP independent.

Cyclic AMP↗

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[Homocystinuria].

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Child↗

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[Iodine levels in salt for human consumption and aspects of iodine prophylaxis in Yugoslavia].

Iodine content of iodinated salt intended only for human consumption was eyamined in samples from all domestic manufacturers (salt mines in: Tuzla, Pag, Ulcinj, Ston, Nin, Seca-Portoroz). Sampling was made from commercially available packs (1 kg) or from food industries (large packs). It was established that iodine content of examined samples (57) varied considerably and ranged from 1.8 to 12.2 mg iodine/kg salt. Iodinated salt from the Tuzla and Pag salt mines contained iodine within the prescribed limits in both small and large packs. Similar finding of iodine content was in the small packs of the Ulcinj salt mines, however, their large packs (10 kg) had a markedly low level of iodine (1.8-4.7 mg). Lower iodine content was also noted in salts (1 kg) from the Nin, Ston and Seca-Portoroz mines. Of the 57 examined samples in 70% iodine content was lower than the prescribed dose (7.6 mg). In addition, some mines had low iodine content in all of the 100% of their respective samples. Ever since iodine prophylaxis was introduced in Yugoslavia a number of factors influenced the decrease of iodine intake by the organism to a considerable degree. The results of our investigations and some epidemiological data indicate that the issue of increasing the amount of iodine from the present 7.6 to 15 mg iodine/kg salt should be reconsidered. Besides, it is necessary to arrange the systematic quality control of iodinated salt.

Goiter↗