[Postnatal development of the cat retina. A qualitative and quantitative electron microscopy study].
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Biomedical subjects
Publications and source records attributed to M Vogel.
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In experimental studies on animals, extracorporal blood irradiation was performed in 3 sheeps and 1 goat by means of 500 Ci 137 cesium source. The sheep died of the sequelae of narcosis, with anaemia being only moderately marked. In the goat a transit dosis of 466566 rad could be applied before the animal died of the sequelae of haemolytic anaemia.
The pre- and postnatal clinical, cytogenetic and embryological findings in a family suffering from trisomy 9p and spinal muscular atrophy are presented. The clinical picture of the "trisomy 9p" -syndrome is delineated. Concurrence of autosomal aberration and spinal muscular atrophy, probably of the Werdnig-Hoffmann type, is discussed.
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Report of the clinical history and the histopathologic findings of the globe of a 38-year-old male patient from Ghana. The clinical picture of sickle-cell disease and Eales' disease is very similar, however, the race of the patient and hemoglobin electrophoresis leave no doubts as to the correct diagnosis.
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Haemolysis was studied before and after extracorporeal irradiation of the blood of 20 chronic lymphadenosis patients. Free haemoglobin, haptoglobin and haemopexin were not affected by irradiation, indicating that no haemolysis was caused by the transit dose accumulated during the applied procedure.
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In 8 outpatients suffering from different stages of chronic lymphatic leukemia extracorporeal irradiation of blood was used. In two cases full remission could be induced. In the other patients leukocytes were reduced to 10000 to 40000. In all patients we found a diminuation of B lymphocytes. Side effects were not observed.
132 consecutive patients were reexamined 1-6.5 years (m = 2.8) after total fasting in hospital. 37 patients had continued to lose weight, 20 patients had maintained their fasting result (+/-2 kg) and 7 patients had slightly regained (less than 1/3 of their weight loss during fast). These 3 groups, totalling 64 patients (48%), were considered successful. Their mean overweight was diminished from 57 to 29%, corresponding to a 60% reduction of mortality in certain age groups. On the other hand, 63 patients (48%) had regained more than 1/3 of their original weight loss. Five patients (4%) were lost to follow-up. Selection of patients and long-term follow-up appeared to have a decisive bearing on long-term results of fasting, whereas factors such as age, sex, degree of overweight, onset of overweight in childhood and sports were without significant effect. From the long-term results presented, it is concluded that under certain conditions fasting in hospital is warranted. Behaviour therapy is a possible alternative in the treatment of obesity.
Microangiopathic hemolytic anemias (MHA) are frequently at the root of metastasizing gastric carcinoma. If the characteristic fragmented erythrocytes ("schistocytes") are found to be increased in the blood smear, this can be taken as a pointer to gastric neoplasm. Consumption coagulopathy frequently intensifies the clinical symptoms. A report of a 51-year-old woman with gastric carcinoma, MHA and consumption coagulopathy is given in whom the determination of numerous schistocytes in the peripheral blood was of decisive significance for the diagnosis.
During the 12 month period June 1974-June 1975, 170 patients were advised on termination of pregnancy in the University Department of Obstetrics and Gynaecology, Mannheim, the results from 145 women are discussed. 74% of the women were married, the majority of whom were between 34-39 years old. 39% lived in bad, 40% in average and 21% in good social conditions. In 77 women the pregnancy was terminated after permission was granted from the health authority. In 43 patients the termination was not granted and 25 women did not return to the clinic when an expert opinion was demanded. In 50 women a definitive sterilisation was carried out at the same time as termination of the pregnancy.
Radiation therapy of 26 patients with choroidal metastases from breast cancer has been reviewed. At the time of initial diagnosis of choroidal metastases 13 patients had bilateral choroidal metastases. The median age of the patients was 54 years and the survival from the first symptom of choroidal metastases varied from 2 to 45 months with a median survival of 9.5 months. End results of radiation therapy had been recorded in 22 patients. Local radiation therapy improved vision permanently in 16 patients.